Atlas of Genetics and Cytogenetics in Oncology and Haematology


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NEUROG1 (neurogenin 1)

Identity

Alias_namesNEUROD3
Alias_symbol (synonym)AKA
Math4C
ngn1
bHLHa6
Other alias
HGNC (Hugo) NEUROG1
LocusID (NCBI) 4762
Atlas_Id 52332
Location 5q31.1  [Link to chromosome band 5q31]
Location_base_pair Starts at 135534282 and ends at 135535949 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)NEUROG1   7764
Cards
Entrez_Gene (NCBI)NEUROG1  4762  neurogenin 1
AliasesAKA; Math4C; NEUROD3; bHLHa6; 
ngn1
GeneCards (Weizmann)NEUROG1
Ensembl hg19 (Hinxton)ENSG00000181965 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000181965 [Gene_View]  chr5:135534282-135535949 [Contig_View]  NEUROG1 [Vega]
ICGC DataPortalENSG00000181965
TCGA cBioPortalNEUROG1
AceView (NCBI)NEUROG1
Genatlas (Paris)NEUROG1
WikiGenes4762
SOURCE (Princeton)NEUROG1
Genetics Home Reference (NIH)NEUROG1
Genomic and cartography
GoldenPath hg38 (UCSC)NEUROG1  -     chr5:135534282-135535949 -  5q31.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)NEUROG1  -     5q31.1   [Description]    (hg19-Feb_2009)
EnsemblNEUROG1 - 5q31.1 [CytoView hg19]  NEUROG1 - 5q31.1 [CytoView hg38]
Mapping of homologs : NCBINEUROG1 [Mapview hg19]  NEUROG1 [Mapview hg38]
OMIM601726   
Gene and transcription
Genbank (Entrez)AB593107 AK314280 BC008687 BC028226 BT019366
RefSeq transcript (Entrez)NM_006161
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)NEUROG1
Cluster EST : UnigeneHs.248149 [ NCBI ]
CGAP (NCI)Hs.248149
Alternative Splicing GalleryENSG00000181965
Gene ExpressionNEUROG1 [ NCBI-GEO ]   NEUROG1 [ EBI - ARRAY_EXPRESS ]   NEUROG1 [ SEEK ]   NEUROG1 [ MEM ]
Gene Expression Viewer (FireBrowse)NEUROG1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)4762
GTEX Portal (Tissue expression)NEUROG1
Human Protein AtlasENSG00000181965-NEUROG1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ92886   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ92886  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ92886
Splice isoforms : SwissVarQ92886
PhosPhoSitePlusQ92886
Domaine pattern : Prosite (Expaxy)BHLH (PS50888)   
Domains : Interpro (EBI)bHLH_dom    Ngn1   
Domain families : Pfam (Sanger)HLH (PF00010)   
Domain families : Pfam (NCBI)pfam00010   
Domain families : Smart (EMBL)HLH (SM00353)  
Conserved Domain (NCBI)NEUROG1
DMDM Disease mutations4762
Blocks (Seattle)NEUROG1
SuperfamilyQ92886
Human Protein Atlas [tissue]ENSG00000181965-NEUROG1 [tissue]
Peptide AtlasQ92886
HPRD03430
IPIIPI00023867   
Protein Interaction databases
DIP (DOE-UCLA)Q92886
IntAct (EBI)Q92886
FunCoupENSG00000181965
BioGRIDNEUROG1
STRING (EMBL)NEUROG1
ZODIACNEUROG1
Ontologies - Pathways
QuickGOQ92886
Ontology : AmiGOtranscription factor activity, transcription factor binding  DNA binding  chromatin binding  transcription factor activity, sequence-specific DNA binding  protein binding  nucleus  transcription, DNA-templated  regulation of transcription from RNA polymerase II promoter  thorax and anterior abdomen determination  nervous system development  trigeminal nerve development  vestibulocochlear nerve formation  neuron differentiation  peristalsis  auditory behavior  positive regulation of exit from mitosis  genitalia morphogenesis  inner ear morphogenesis  protein homodimerization activity  perikaryon  cell fate commitment  positive regulation of neuron differentiation  positive regulation of transcription from RNA polymerase II promoter  regulation of muscle organ development  genitalia development  inner ear development  neuromuscular process controlling balance  positive regulation of sequence-specific DNA binding transcription factor activity  palate development  E-box binding  E-box binding  mastication  cochlea development  cochlea morphogenesis  craniofacial suture morphogenesis  learned vocalization behavior  negative regulation of relaxation of muscle  negative regulation of saliva secretion  hard palate morphogenesis  sequence-specific double-stranded DNA binding  
Ontology : EGO-EBItranscription factor activity, transcription factor binding  DNA binding  chromatin binding  transcription factor activity, sequence-specific DNA binding  protein binding  nucleus  transcription, DNA-templated  regulation of transcription from RNA polymerase II promoter  thorax and anterior abdomen determination  nervous system development  trigeminal nerve development  vestibulocochlear nerve formation  neuron differentiation  peristalsis  auditory behavior  positive regulation of exit from mitosis  genitalia morphogenesis  inner ear morphogenesis  protein homodimerization activity  perikaryon  cell fate commitment  positive regulation of neuron differentiation  positive regulation of transcription from RNA polymerase II promoter  regulation of muscle organ development  genitalia development  inner ear development  neuromuscular process controlling balance  positive regulation of sequence-specific DNA binding transcription factor activity  palate development  E-box binding  E-box binding  mastication  cochlea development  cochlea morphogenesis  craniofacial suture morphogenesis  learned vocalization behavior  negative regulation of relaxation of muscle  negative regulation of saliva secretion  hard palate morphogenesis  sequence-specific double-stranded DNA binding  
NDEx NetworkNEUROG1
Atlas of Cancer Signalling NetworkNEUROG1
Wikipedia pathwaysNEUROG1
Orthology - Evolution
OrthoDB4762
GeneTree (enSembl)ENSG00000181965
Phylogenetic Trees/Animal Genes : TreeFamNEUROG1
HOVERGENQ92886
HOGENOMQ92886
Homologs : HomoloGeneNEUROG1
Homology/Alignments : Family Browser (UCSC)NEUROG1
Gene fusions - Rearrangements
Fusion: Tumor Portal NEUROG1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerNEUROG1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)NEUROG1
dbVarNEUROG1
ClinVarNEUROG1
1000_GenomesNEUROG1 
Exome Variant ServerNEUROG1
ExAC (Exome Aggregation Consortium)ENSG00000181965
GNOMAD BrowserENSG00000181965
Genetic variants : HAPMAP4762
Genomic Variants (DGV)NEUROG1 [DGVbeta]
DECIPHERNEUROG1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisNEUROG1 
Mutations
ICGC Data PortalNEUROG1 
TCGA Data PortalNEUROG1 
Broad Tumor PortalNEUROG1
OASIS PortalNEUROG1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICNEUROG1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDNEUROG1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch NEUROG1
DgiDB (Drug Gene Interaction Database)NEUROG1
DoCM (Curated mutations)NEUROG1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)NEUROG1 (select a term)
intoGenNEUROG1
Cancer3DNEUROG1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM601726   
Orphanet
MedgenNEUROG1
Genetic Testing Registry NEUROG1
NextProtQ92886 [Medical]
TSGene4762
GENETestsNEUROG1
Target ValidationNEUROG1
Huge Navigator NEUROG1 [HugePedia]
snp3D : Map Gene to Disease4762
BioCentury BCIQNEUROG1
ClinGenNEUROG1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD4762
Chemical/Pharm GKB GenePA31569
Clinical trialNEUROG1
Miscellaneous
canSAR (ICR)NEUROG1 (select the gene name)
Probes
Litterature
PubMed22 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineNEUROG1
EVEXNEUROG1
GoPubMedNEUROG1
iHOPNEUROG1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu Nov 9 13:02:31 CET 2017

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