NEUROG2 (neurogenin 2)

2014-11-01  

Identity

HGNC
LOCATION
4q25
LOCUSID
ALIAS
Atoh4,Math4A,NGN2,bHLHa8,ngn-2

Other Information

Locus ID:

NCBI: 63973
MIM: 606624
HGNC: 13805
Ensembl: ENSG00000178403

Variants:

dbSNP: 63973
ClinVar: 63973
TCGA: ENSG00000178403
COSMIC: NEUROG2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000178403ENST00000313341Q9H2A3

Expression (GTEx)

0
5
10
15
20

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
254037532014Rapid neurogenesis through transcriptional activation in human stem cells.59
297918592018Combining NGN2 Programming with Developmental Patterning Generates Human Excitatory Neurons with NMDAR-Mediated Synaptic Transmission.21
182421862008Proneural bHLH neurogenin 2 differentially regulates Nurr1-induced dopamine neuron differentiation in rat and mouse neural precursor cells in vitro.17
212099092010Grafted human embryonic progenitors expressing neurogenin-2 stimulate axonal sprouting and improve motor recovery after severe spinal cord injury.15
177848402007Neurospheres derived from human embryoid bodies treated with retinoic Acid show an increase in nestin and ngn2 expression that correlates with the proportion of tyrosine hydroxylase-positive cells.10
203320992010A systematic gene-based screen of chr4q22-q32 identifies association of a novel susceptibility gene, DKK2, with the quantitative trait of alcohol dependence symptom counts.8
259124332015Neurogenin 2 enhances the generation of patient-specific induced neuronal cells.5
198793282010Genetic analysis of the NEUROG2 gene in patients with Parkinson's disease.0
198793282010Genetic analysis of the NEUROG2 gene in patients with Parkinson's disease.0

Citation

Dessen P

NEUROG2 (neurogenin 2)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/70808/neurog2