Atlas of Genetics and Cytogenetics in Oncology and Haematology


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NEUROG3 (neurogenin 3)

Identity

Alias_symbol (synonym)Atoh5
Math4B
ngn3
bHLHa7
Other aliasNGN-3
HGNC (Hugo) NEUROG3
LocusID (NCBI) 50674
Atlas_Id 50918
Location 10q22.1  [Link to chromosome band 10q22]
Location_base_pair Starts at 69572035 and ends at 69573454 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)NEUROG3   13806
Cards
Entrez_Gene (NCBI)NEUROG3  50674  neurogenin 3
AliasesAtoh5; Math4B; NGN-3; bHLHa7; 
ngn3
GeneCards (Weizmann)NEUROG3
Ensembl hg19 (Hinxton)ENSG00000122859 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000122859 [Gene_View]  chr10:69572035-69573454 [Contig_View]  NEUROG3 [Vega]
ICGC DataPortalENSG00000122859
TCGA cBioPortalNEUROG3
AceView (NCBI)NEUROG3
Genatlas (Paris)NEUROG3
WikiGenes50674
SOURCE (Princeton)NEUROG3
Genetics Home Reference (NIH)NEUROG3
Genomic and cartography
GoldenPath hg38 (UCSC)NEUROG3  -     chr10:69572035-69573454 -  10q22.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)NEUROG3  -     10q22.1   [Description]    (hg19-Feb_2009)
EnsemblNEUROG3 - 10q22.1 [CytoView hg19]  NEUROG3 - 10q22.1 [CytoView hg38]
Mapping of homologs : NCBINEUROG3 [Mapview hg19]  NEUROG3 [Mapview hg38]
OMIM604882   610370   
Gene and transcription
Genbank (Entrez)AK313952 BC069098 BC074938 BC074939 BC117488
RefSeq transcript (Entrez)NM_020999
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)NEUROG3
Cluster EST : UnigeneHs.532682 [ NCBI ]
CGAP (NCI)Hs.532682
Alternative Splicing GalleryENSG00000122859
Gene ExpressionNEUROG3 [ NCBI-GEO ]   NEUROG3 [ EBI - ARRAY_EXPRESS ]   NEUROG3 [ SEEK ]   NEUROG3 [ MEM ]
Gene Expression Viewer (FireBrowse)NEUROG3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)50674
GTEX Portal (Tissue expression)NEUROG3
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9Y4Z2   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9Y4Z2  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9Y4Z2
Splice isoforms : SwissVarQ9Y4Z2
PhosPhoSitePlusQ9Y4Z2
Domaine pattern : Prosite (Expaxy)BHLH (PS50888)   
Domains : Interpro (EBI)bHLH_dom    Ngn3   
Domain families : Pfam (Sanger)HLH (PF00010)   
Domain families : Pfam (NCBI)pfam00010   
Domain families : Smart (EMBL)HLH (SM00353)  
Conserved Domain (NCBI)NEUROG3
DMDM Disease mutations50674
Blocks (Seattle)NEUROG3
SuperfamilyQ9Y4Z2
Human Protein AtlasENSG00000122859
Peptide AtlasQ9Y4Z2
HPRD05346
IPIIPI00025789   
Protein Interaction databases
DIP (DOE-UCLA)Q9Y4Z2
IntAct (EBI)Q9Y4Z2
FunCoupENSG00000122859
BioGRIDNEUROG3
STRING (EMBL)NEUROG3
ZODIACNEUROG3
Ontologies - Pathways
QuickGOQ9Y4Z2
Ontology : AmiGOnegative regulation of transcription from RNA polymerase II promoter  RNA polymerase II core promoter proximal region sequence-specific DNA binding  core promoter binding  transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding  transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding  transcription coactivator activity  protein binding  nucleus  cytoplasm  transcription from RNA polymerase II promoter  nervous system development  central nervous system development  peripheral nervous system development  spinal cord development  epithelial cell differentiation  forebrain development  hindbrain development  endocrine pancreas development  chromatin DNA binding  positive regulation of neuron differentiation  positive regulation of transcription from RNA polymerase II promoter  protein dimerization activity  regulation of dendrite morphogenesis  positive regulation of sequence-specific DNA binding transcription factor activity  transdifferentiation  
Ontology : EGO-EBInegative regulation of transcription from RNA polymerase II promoter  RNA polymerase II core promoter proximal region sequence-specific DNA binding  core promoter binding  transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding  transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding  transcription coactivator activity  protein binding  nucleus  cytoplasm  transcription from RNA polymerase II promoter  nervous system development  central nervous system development  peripheral nervous system development  spinal cord development  epithelial cell differentiation  forebrain development  hindbrain development  endocrine pancreas development  chromatin DNA binding  positive regulation of neuron differentiation  positive regulation of transcription from RNA polymerase II promoter  protein dimerization activity  regulation of dendrite morphogenesis  positive regulation of sequence-specific DNA binding transcription factor activity  transdifferentiation  
Pathways : KEGGMaturity onset diabetes of the young   
NDEx NetworkNEUROG3
Atlas of Cancer Signalling NetworkNEUROG3
Wikipedia pathwaysNEUROG3
Orthology - Evolution
OrthoDB50674
GeneTree (enSembl)ENSG00000122859
Phylogenetic Trees/Animal Genes : TreeFamNEUROG3
HOVERGENQ9Y4Z2
HOGENOMQ9Y4Z2
Homologs : HomoloGeneNEUROG3
Homology/Alignments : Family Browser (UCSC)NEUROG3
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerNEUROG3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)NEUROG3
dbVarNEUROG3
ClinVarNEUROG3
1000_GenomesNEUROG3 
Exome Variant ServerNEUROG3
ExAC (Exome Aggregation Consortium)NEUROG3 (select the gene name)
Genetic variants : HAPMAP50674
Genomic Variants (DGV)NEUROG3 [DGVbeta]
DECIPHERNEUROG3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisNEUROG3 
Mutations
ICGC Data PortalNEUROG3 
TCGA Data PortalNEUROG3 
Broad Tumor PortalNEUROG3
OASIS PortalNEUROG3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICNEUROG3  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDNEUROG3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch NEUROG3
DgiDB (Drug Gene Interaction Database)NEUROG3
DoCM (Curated mutations)NEUROG3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)NEUROG3 (select a term)
intoGenNEUROG3
Cancer3DNEUROG3(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM604882    610370   
Orphanet11598   
MedgenNEUROG3
Genetic Testing Registry NEUROG3
NextProtQ9Y4Z2 [Medical]
TSGene50674
GENETestsNEUROG3
Target ValidationNEUROG3
Huge Navigator NEUROG3 [HugePedia]
snp3D : Map Gene to Disease50674
BioCentury BCIQNEUROG3
ClinGenNEUROG3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD50674
Chemical/Pharm GKB GenePA31571
Clinical trialNEUROG3
Miscellaneous
canSAR (ICR)NEUROG3 (select the gene name)
Probes
Litterature
PubMed42 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineNEUROG3
EVEXNEUROG3
GoPubMedNEUROG3
iHOPNEUROG3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Sep 18 14:01:32 CEST 2017

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