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NEXN (nexilin (F actin binding protein))

Identity

Other namesCMH20
NELIN
HGNC (Hugo) NEXN
LocusID (NCBI) 91624
Location 1p31.1
Location_base_pair Starts at 78354200 and ends at 78409578 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

External links

Nomenclature
HGNC (Hugo)NEXN   29557
Cards
Entrez_Gene (NCBI)NEXN  91624  nexilin (F actin binding protein)
GeneCards (Weizmann)NEXN
Ensembl hg19 (Hinxton)ENSG00000162614 [Gene_View]  chr1:78354200-78409578 [Contig_View]  NEXN [Vega]
Ensembl hg38 (Hinxton)ENSG00000162614 [Gene_View]  chr1:78354200-78409578 [Contig_View]  NEXN [Vega]
ICGC DataPortalENSG00000162614
cBioPortalNEXN
AceView (NCBI)NEXN
Genatlas (Paris)NEXN
WikiGenes91624
SOURCE (Princeton)NEXN
Genomic and cartography
GoldenPath hg19 (UCSC)NEXN  -     chr1:78354200-78409578 +  1p31.1   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)NEXN  -     1p31.1   [Description]    (hg38-Dec_2013)
EnsemblNEXN - 1p31.1 [CytoView hg19]  NEXN - 1p31.1 [CytoView hg38]
Mapping of homologs : NCBINEXN [Mapview hg19]  NEXN [Mapview hg38]
OMIM613121   613122   613876   
Gene and transcription
Genbank (Entrez)AA249326 AF114264 AF176780 AK057954 AK127535
RefSeq transcript (Entrez)NM_001172309 NM_144573
RefSeq genomic (Entrez)AC_000133 NC_000001 NC_018912 NG_016625 NT_032977 NW_001838579 NW_004929290
Consensus coding sequences : CCDS (NCBI)NEXN
Cluster EST : UnigeneHs.612385 [ NCBI ]
CGAP (NCI)Hs.612385
Alternative Splicing : Fast-db (Paris)GSHG0000647
Alternative Splicing GalleryENSG00000162614
Gene ExpressionNEXN [ NCBI-GEO ]     NEXN [ SEEK ]   NEXN [ MEM ]
SOURCE (Princeton)Expression in : [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ0ZGT2 (Uniprot)
NextProtQ0ZGT2  [Medical]
With graphics : InterProQ0ZGT2
Splice isoforms : SwissVarQ0ZGT2 (Swissvar)
Domaine pattern : Prosite (Expaxy)IG_LIKE (PS50835)   
Domains : Interpro (EBI)Ig-like_dom    Ig-like_fold    Ig_I-set    Ig_sub    Myosin_light_ch_kinase-rel   
Related proteins : CluSTrQ0ZGT2
Domain families : Pfam (Sanger)I-set (PF07679)   
Domain families : Pfam (NCBI)pfam07679   
Domain families : Smart (EMBL)IG (SM00409)  
DMDM Disease mutations91624
Blocks (Seattle)Q0ZGT2
Human Protein AtlasENSG00000162614
Peptide AtlasQ0ZGT2
HPRD11388
IPIIPI00180404   IPI00514299   IPI00855737   IPI00554751   IPI00384447   IPI00873443   IPI00385083   
Protein Interaction databases
DIP (DOE-UCLA)Q0ZGT2
IntAct (EBI)Q0ZGT2
FunCoupENSG00000162614
BioGRIDNEXN
IntegromeDBNEXN
STRING (EMBL)NEXN
Ontologies - Pathways
QuickGOQ0ZGT2
Ontology : AmiGOcalmodulin-dependent protein kinase activity  cytoskeleton  cell-substrate adherens junction  protein phosphorylation  structural constituent of muscle  Z disc  Z disc  regulation of cell migration  regulation of apoptotic process  cardiac muscle fiber development  actin filament binding  regulation of cytoskeleton organization  
Ontology : EGO-EBIcalmodulin-dependent protein kinase activity  cytoskeleton  cell-substrate adherens junction  protein phosphorylation  structural constituent of muscle  Z disc  Z disc  regulation of cell migration  regulation of apoptotic process  cardiac muscle fiber development  actin filament binding  regulation of cytoskeleton organization  
Protein Interaction DatabaseNEXN
DoCM (Curated mutations)NEXN
Wikipedia pathwaysNEXN
Gene fusion - rearrangements
Polymorphisms : SNP, variants
NCBI Variation ViewerNEXN [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)NEXN
dbVarNEXN
ClinVarNEXN
1000_GenomesNEXN 
Exome Variant ServerNEXN
SNP (GeneSNP Utah)NEXN
SNP : HGBaseNEXN
Genetic variants : HAPMAPNEXN
Genomic VariantsNEXN  NEXN [DGVbeta]
Mutations
ICGC Data PortalENSG00000162614 
Somatic Mutations in Cancer : COSMICNEXN 
CONAN: Copy Number AnalysisNEXN 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)1:78354200-78409578
Mutations and Diseases : HGMDNEXN
OMIM613121    613122    613876   
MedgenNEXN
NextProtQ0ZGT2 [Medical]
GENETestsNEXN
Disease Genetic AssociationNEXN
Huge Navigator NEXN [HugePedia]  NEXN [HugeCancerGEM]
snp3D : Map Gene to Disease91624
DGIdb (Drug Gene Interaction db)NEXN
General knowledge
Homologs : HomoloGeneNEXN
Homology/Alignments : Family Browser (UCSC)NEXN
Phylogenetic Trees/Animal Genes : TreeFamNEXN
Chemical/Protein Interactions : CTD91624
Chemical/Pharm GKB GenePA134974801
Clinical trialNEXN
Cancer Resource (Charite)ENSG00000162614
Other databases
Probes
Litterature
PubMed21 Pubmed reference(s) in Entrez
CoreMineNEXN
GoPubMedNEXN
iHOPNEXN
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2014Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Sun Dec 21 00:27:00 CET 2014

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