Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

NFIC (nuclear factor I C)

Identity

Alias_namesNFI
nuclear factor I/C (CCAAT-binding transcription factor)
Alias_symbol (synonym)CTF
NF-I
CTF5
Other alias
HGNC (Hugo) NFIC
LocusID (NCBI) 4782
Atlas_Id 51783
Location 19p13.3  [Link to chromosome band 19p13]
Location_base_pair Starts at 3366565 and ends at 3469215 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
ARHGAP17 (16p12.1) / NFIC (19p13.3)FZR1 (19p13.3) / NFIC (19p13.3)GRID1 (10q23.1) / NFIC (19p13.3)
LRTOMT (11q13.4) / NFIC (19p13.3)NFIC (19p13.3) / C1orf186 (1q32.1)NFIC (19p13.3) / CELF5 (19p13.3)
NFIC (19p13.3) / NFIC (19p13.3)NFIC (19p13.3) / VSTM4 (10q11.23)NFIC (19p13.3) / WDR18 (19p13.3)
PIP5K1C (19p13.3) / NFIC (19p13.3)STK39 (2q24.3) / NFIC (19p13.3)TM6SF1 (15q25.2) / NFIC (19p13.3)
ZNF653 (19p13.2) / NFIC (19p13.3)FZR1 19p13.3 / NFIC 19p13.3LRTOMT 11q13.4 / NFIC 19p13.3
NFIC 19p13.3 / CELF5 19p13.3NFIC 19p13.3 / WDR18 19p13.3ZNF653 19p13.2 / NFIC 19p13.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)NFIC   7786
Cards
Entrez_Gene (NCBI)NFIC  4782  nuclear factor I C
AliasesCTF; CTF5; NF-I; NFI
GeneCards (Weizmann)NFIC
Ensembl hg19 (Hinxton)ENSG00000141905 [Gene_View]  chr19:3366565-3469215 [Contig_View]  NFIC [Vega]
Ensembl hg38 (Hinxton)ENSG00000141905 [Gene_View]  chr19:3366565-3469215 [Contig_View]  NFIC [Vega]
ICGC DataPortalENSG00000141905
TCGA cBioPortalNFIC
AceView (NCBI)NFIC
Genatlas (Paris)NFIC
WikiGenes4782
SOURCE (Princeton)NFIC
Genetics Home Reference (NIH)NFIC
Genomic and cartography
GoldenPath hg19 (UCSC)NFIC  -     chr19:3366565-3469215 +  19p13.3   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)NFIC  -     19p13.3   [Description]    (hg38-Dec_2013)
EnsemblNFIC - 19p13.3 [CytoView hg19]  NFIC - 19p13.3 [CytoView hg38]
Mapping of homologs : NCBINFIC [Mapview hg19]  NFIC [Mapview hg38]
OMIM600729   
Gene and transcription
Genbank (Entrez)AK129956 AK289885 AK297825 AK297867 AK304816
RefSeq transcript (Entrez)NM_001245002 NM_001245004 NM_001245005 NM_005597 NM_205843
RefSeq genomic (Entrez)NC_000019 NC_018930 NG_030333 NT_011295 NW_004929412
Consensus coding sequences : CCDS (NCBI)NFIC
Cluster EST : UnigeneHs.170131 [ NCBI ]
CGAP (NCI)Hs.170131
Alternative Splicing GalleryENSG00000141905
Gene ExpressionNFIC [ NCBI-GEO ]   NFIC [ EBI - ARRAY_EXPRESS ]   NFIC [ SEEK ]   NFIC [ MEM ]
Gene Expression Viewer (FireBrowse)NFIC [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)4782
GTEX Portal (Tissue expression)NFIC
Protein : pattern, domain, 3D structure
UniProt/SwissProtP08651   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP08651  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP08651
Splice isoforms : SwissVarP08651
PhosPhoSitePlusP08651
Domaine pattern : Prosite (Expaxy)CTF_NFI_1 (PS00349)    CTF_NFI_2 (PS51080)   
Domains : Interpro (EBI)CTF/NFI    CTF/NFI_DNA-bd-dom    CTF/NFI_DNA-bd_CS    CTF/NFI_DNA-bd_N    MAD_homology1_Dwarfin-type   
Domain families : Pfam (Sanger)CTF_NFI (PF00859)    MH1 (PF03165)    NfI_DNAbd_pre-N (PF10524)   
Domain families : Pfam (NCBI)pfam00859    pfam03165    pfam10524   
Domain families : Smart (EMBL)DWA (SM00523)  
Conserved Domain (NCBI)NFIC
DMDM Disease mutations4782
Blocks (Seattle)NFIC
SuperfamilyP08651
Human Protein AtlasENSG00000141905
Peptide AtlasP08651
IPIIPI00029795   IPI00941207   IPI00218037   IPI00218039   IPI00218041   IPI01026493   IPI01015986   
Protein Interaction databases
DIP (DOE-UCLA)P08651
IntAct (EBI)P08651
FunCoupENSG00000141905
BioGRIDNFIC
STRING (EMBL)NFIC
ZODIACNFIC
Ontologies - Pathways
QuickGOP08651
Ontology : AmiGOnegative regulation of transcription from RNA polymerase II promoter  negative regulation of transcription from RNA polymerase II promoter  RNA polymerase II core promoter proximal region sequence-specific DNA binding  transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding  transcription factor activity, sequence-specific DNA binding  nucleus  nucleus  nucleolus  DNA replication  transcription from RNA polymerase II promoter  odontogenesis of dentin-containing tooth  positive regulation of transcription from RNA polymerase II promoter  
Ontology : EGO-EBInegative regulation of transcription from RNA polymerase II promoter  negative regulation of transcription from RNA polymerase II promoter  RNA polymerase II core promoter proximal region sequence-specific DNA binding  transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding  transcription factor activity, sequence-specific DNA binding  nucleus  nucleus  nucleolus  DNA replication  transcription from RNA polymerase II promoter  odontogenesis of dentin-containing tooth  positive regulation of transcription from RNA polymerase II promoter  
NDEx NetworkNFIC
Atlas of Cancer Signalling NetworkNFIC
Wikipedia pathwaysNFIC
Orthology - Evolution
OrthoDB4782
GeneTree (enSembl)ENSG00000141905
Phylogenetic Trees/Animal Genes : TreeFamNFIC
HOVERGENP08651
HOGENOMP08651
Homologs : HomoloGeneNFIC
Homology/Alignments : Family Browser (UCSC)NFIC
Gene fusions - Rearrangements
Fusion : MitelmanFZR1/NFIC [19p13.3/19p13.3]  [t(19;19)(p13;p13)]  
Fusion : MitelmanLRTOMT/NFIC [11q13.4/19p13.3]  [t(11;19)(q13;p13)]  
Fusion : MitelmanNFIC/CELF5 [19p13.3/19p13.3]  [t(19;19)(p13;p13)]  
Fusion : MitelmanNFIC/WDR18 [19p13.3/19p13.3]  [t(19;19)(p13;p13)]  
Fusion : MitelmanZNF653/NFIC [19p13.2/19p13.3]  [t(19;19)(p13;p13)]  
Fusion: TCGAFZR1 19p13.3 NFIC 19p13.3 BRCA
Fusion: TCGALRTOMT 11q13.4 NFIC 19p13.3 BRCA
Fusion: TCGANFIC 19p13.3 CELF5 19p13.3 LGG
Fusion: TCGANFIC 19p13.3 WDR18 19p13.3 BRCA
Fusion: TCGAZNF653 19p13.2 NFIC 19p13.3 LUSC
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerNFIC [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)NFIC
dbVarNFIC
ClinVarNFIC
1000_GenomesNFIC 
Exome Variant ServerNFIC
ExAC (Exome Aggregation Consortium)NFIC (select the gene name)
Genetic variants : HAPMAP4782
Genomic Variants (DGV)NFIC [DGVbeta]
DECIPHER (Syndromes)19:3366565-3469215  ENSG00000141905
CONAN: Copy Number AnalysisNFIC 
Mutations
ICGC Data PortalNFIC 
TCGA Data PortalNFIC 
Broad Tumor PortalNFIC
OASIS PortalNFIC [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICNFIC  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDNFIC
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch NFIC
DgiDB (Drug Gene Interaction Database)NFIC
DoCM (Curated mutations)NFIC (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)NFIC (select a term)
intoGenNFIC
Cancer3DNFIC(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM600729   
Orphanet
MedgenNFIC
Genetic Testing Registry NFIC
NextProtP08651 [Medical]
TSGene4782
GENETestsNFIC
Huge Navigator NFIC [HugePedia]
snp3D : Map Gene to Disease4782
BioCentury BCIQNFIC
ClinGenNFIC
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD4782
Chemical/Pharm GKB GenePA31592
Clinical trialNFIC
Miscellaneous
canSAR (ICR)NFIC (select the gene name)
Probes
Litterature
PubMed52 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineNFIC
EVEXNFIC
GoPubMedNFIC
iHOPNFIC
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Mar 14 13:18:44 CET 2017

Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.