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NFIL3 (nuclear factor, interleukin 3 regulated)

Identity

Alias_namesIL3BP1
Alias_symbol (synonym)E4BP4
NFIL3A
NF-IL3A
Other alias
HGNC (Hugo) NFIL3
LocusID (NCBI) 4783
Atlas_Id 53422
Location 9q22.31  [Link to chromosome band 9q22]
Location_base_pair Starts at 91409045 and ends at 91423862 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
LARP4 (12q13.12) / NFIL3 (9q22.31)NAIP (5q13.2) / NFIL3 (9q22.31)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)NFIL3   7787
Cards
Entrez_Gene (NCBI)NFIL3  4783  nuclear factor, interleukin 3 regulated
AliasesE4BP4; IL3BP1; NF-IL3A; NFIL3A
GeneCards (Weizmann)NFIL3
Ensembl hg19 (Hinxton)ENSG00000165030 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000165030 [Gene_View]  ENSG00000165030 [Sequence]  chr9:91409045-91423862 [Contig_View]  NFIL3 [Vega]
ICGC DataPortalENSG00000165030
TCGA cBioPortalNFIL3
AceView (NCBI)NFIL3
Genatlas (Paris)NFIL3
WikiGenes4783
SOURCE (Princeton)NFIL3
Genetics Home Reference (NIH)NFIL3
Genomic and cartography
GoldenPath hg38 (UCSC)NFIL3  -     chr9:91409045-91423862 -  9q22.31   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)NFIL3  -     9q22.31   [Description]    (hg19-Feb_2009)
EnsemblNFIL3 - 9q22.31 [CytoView hg19]  NFIL3 - 9q22.31 [CytoView hg38]
Mapping of homologs : NCBINFIL3 [Mapview hg19]  NFIL3 [Mapview hg38]
OMIM605327   
Gene and transcription
Genbank (Entrez)AK313970 AW163045 BC008197 BQ937243 CR542049
RefSeq transcript (Entrez)NM_001289999 NM_001290000 NM_005384
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)NFIL3
Cluster EST : UnigeneHs.79334 [ NCBI ]
CGAP (NCI)Hs.79334
Alternative Splicing GalleryENSG00000165030
Gene ExpressionNFIL3 [ NCBI-GEO ]   NFIL3 [ EBI - ARRAY_EXPRESS ]   NFIL3 [ SEEK ]   NFIL3 [ MEM ]
Gene Expression Viewer (FireBrowse)NFIL3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)4783
GTEX Portal (Tissue expression)NFIL3
Human Protein AtlasENSG00000165030-NFIL3 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ16649   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ16649  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ16649
Splice isoforms : SwissVarQ16649
PhosPhoSitePlusQ16649
Domaine pattern : Prosite (Expaxy)BZIP (PS50217)    BZIP_BASIC (PS00036)   
Domains : Interpro (EBI)bZIP    NFIL3/E4BP4    Vert_IL3-reg_TF   
Domain families : Pfam (Sanger)bZIP_2 (PF07716)    Vert_IL3-reg_TF (PF06529)   
Domain families : Pfam (NCBI)pfam07716    pfam06529   
Domain families : Smart (EMBL)BRLZ (SM00338)  
Conserved Domain (NCBI)NFIL3
DMDM Disease mutations4783
Blocks (Seattle)NFIL3
SuperfamilyQ16649
Human Protein Atlas [tissue]ENSG00000165030-NFIL3 [tissue]
Peptide AtlasQ16649
HPRD05619
IPIIPI00290562   IPI00983119   
Protein Interaction databases
DIP (DOE-UCLA)Q16649
IntAct (EBI)Q16649
FunCoupENSG00000165030
BioGRIDNFIL3
STRING (EMBL)NFIL3
ZODIACNFIL3
Ontologies - Pathways
QuickGOQ16649
Ontology : AmiGOnegative regulation of transcription by RNA polymerase II  RNA polymerase II regulatory region sequence-specific DNA binding  RNA polymerase II proximal promoter sequence-specific DNA binding  transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding  DNA binding  DNA binding transcription factor activity  transcription corepressor activity  protein binding  nucleus  transcription by RNA polymerase II  immune response  circadian rhythm  positive regulation of gene expression  cellular response to interleukin-4  
Ontology : EGO-EBInegative regulation of transcription by RNA polymerase II  RNA polymerase II regulatory region sequence-specific DNA binding  RNA polymerase II proximal promoter sequence-specific DNA binding  transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding  DNA binding  DNA binding transcription factor activity  transcription corepressor activity  protein binding  nucleus  transcription by RNA polymerase II  immune response  circadian rhythm  positive regulation of gene expression  cellular response to interleukin-4  
NDEx NetworkNFIL3
Atlas of Cancer Signalling NetworkNFIL3
Wikipedia pathwaysNFIL3
Orthology - Evolution
OrthoDB4783
GeneTree (enSembl)ENSG00000165030
Phylogenetic Trees/Animal Genes : TreeFamNFIL3
HOVERGENQ16649
HOGENOMQ16649
Homologs : HomoloGeneNFIL3
Homology/Alignments : Family Browser (UCSC)NFIL3
Gene fusions - Rearrangements
Fusion : QuiverNFIL3
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerNFIL3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)NFIL3
dbVarNFIL3
ClinVarNFIL3
1000_GenomesNFIL3 
Exome Variant ServerNFIL3
ExAC (Exome Aggregation Consortium)ENSG00000165030
GNOMAD BrowserENSG00000165030
Genetic variants : HAPMAP4783
Genomic Variants (DGV)NFIL3 [DGVbeta]
DECIPHERNFIL3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisNFIL3 
Mutations
ICGC Data PortalNFIL3 
TCGA Data PortalNFIL3 
Broad Tumor PortalNFIL3
OASIS PortalNFIL3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICNFIL3  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDNFIL3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch NFIL3
DgiDB (Drug Gene Interaction Database)NFIL3
DoCM (Curated mutations)NFIL3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)NFIL3 (select a term)
intoGenNFIL3
Cancer3DNFIL3(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM605327   
Orphanet
DisGeNETNFIL3
MedgenNFIL3
Genetic Testing Registry NFIL3
NextProtQ16649 [Medical]
TSGene4783
GENETestsNFIL3
Target ValidationNFIL3
Huge Navigator NFIL3 [HugePedia]
snp3D : Map Gene to Disease4783
BioCentury BCIQNFIL3
ClinGenNFIL3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD4783
Chemical/Pharm GKB GenePA31593
Clinical trialNFIL3
Miscellaneous
canSAR (ICR)NFIL3 (select the gene name)
Probes
Litterature
PubMed41 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineNFIL3
EVEXNFIL3
GoPubMedNFIL3
iHOPNFIL3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Fri Jun 22 16:40:06 CEST 2018
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