Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 4793
MIM: 604495
HGNC: 7798
Ensembl: ENSG00000104825
Variants:
dbSNP: 4793
ClinVar: 4793
TCGA: ENSG00000104825
COSMIC: NFKBIB
RNA/Proteins
Expression (GTEx)
Pathways
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA131301952 | gefitinib | Chemical | ClinicalAnnotation | associated | PD | 31664190 | |
| PA164925725 | Toxic liver disease | Disease | ClinicalAnnotation | associated | PD | 31664190 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 32017069 | 2020 | The NF-κB regulator IκBβ exhibits different molecular interactivity and phosphorylation status from IκBα in an IKK2-catalysed reaction. | 5 |
| 32017069 | 2020 | The NF-κB regulator IκBβ exhibits different molecular interactivity and phosphorylation status from IκBα in an IKK2-catalysed reaction. | 5 |
| 28314790 | 2017 | Selinexor (KPT-330) Induces Tumor Suppression through Nuclear Sequestration of IκB and Downregulation of Survivin. | 23 |
| 28448456 | 2017 | Upregulation of miRNA-4776 in Influenza Virus Infected Bronchial Epithelial Cells Is Associated with Downregulation of NFKBIB and Increased Viral Survival. | 18 |
| 28314790 | 2017 | Selinexor (KPT-330) Induces Tumor Suppression through Nuclear Sequestration of IκB and Downregulation of Survivin. | 23 |
| 28448456 | 2017 | Upregulation of miRNA-4776 in Influenza Virus Infected Bronchial Epithelial Cells Is Associated with Downregulation of NFKBIB and Increased Viral Survival. | 18 |
| 26227166 | 2016 | IKBB tumor suppressive role in nasopharyngeal carcinoma via NF-κB-mediated signalling. | 8 |
| 26227166 | 2016 | IKBB tumor suppressive role in nasopharyngeal carcinoma via NF-κB-mediated signalling. | 8 |
| 25326706 | 2014 | Genetic polymorphisms and risk of recurrent wheezing in pediatric age. | 11 |
| 25326706 | 2014 | Genetic polymorphisms and risk of recurrent wheezing in pediatric age. | 11 |
| 20056178 | 2010 | Polymorphisms in innate immunity genes and patients response to dendritic cell-based HIV immuno-treatment. | 6 |
| 20140262 | 2010 | Maternal and fetal genetic associations of PTGER3 and PON1 with preterm birth. | 17 |
| 20448286 | 2010 | Association between anti-tumour necrosis factor treatment response and genetic variants within the TLR and NF{kappa}B signalling pathways. | 26 |
| 20628086 | 2010 | Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. | 15 |
| 20716621 | 2010 | Genetic polymorphisms in adaptive immunity genes and childhood acute lymphoblastic leukemia. | 12 |
Citation
Dessen P
NFKBIB (NFKB inhibitor beta)
Atlas Genet Cytogenet Oncol Haematol. 2003-08-01
Online version: http://atlasgeneticsoncology.org/gene/41531/nfkbib
