Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

NFRKB (nuclear factor related to kappaB binding protein)

Identity

Alias_symbol (synonym)DKFZp547B2013
INO80G
Other alias
HGNC (Hugo) NFRKB
LocusID (NCBI) 4798
Atlas_Id 52249
Location 11q24.3  [Link to chromosome band 11q24]
Location_base_pair Starts at 129733670 and ends at 129765490 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
HSP90AA1 (14q32.31) / NFRKB (11q24.3)NFRKB (11q24.3) / NFRKB (11q24.3)NFRKB (11q24.3) / NOX4 (11q14.3)
UBE2Q2 (15q24.2) / NFRKB (11q24.3)NFRKB 11q24.3 / NOX4 11q14.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)NFRKB   7802
Cards
Entrez_Gene (NCBI)NFRKB  4798  nuclear factor related to kappaB binding protein
AliasesINO80G
GeneCards (Weizmann)NFRKB
Ensembl hg19 (Hinxton)ENSG00000170322 [Gene_View]  chr11:129733670-129765490 [Contig_View]  NFRKB [Vega]
Ensembl hg38 (Hinxton)ENSG00000170322 [Gene_View]  chr11:129733670-129765490 [Contig_View]  NFRKB [Vega]
ICGC DataPortalENSG00000170322
TCGA cBioPortalNFRKB
AceView (NCBI)NFRKB
Genatlas (Paris)NFRKB
WikiGenes4798
SOURCE (Princeton)NFRKB
Genetics Home Reference (NIH)NFRKB
Genomic and cartography
GoldenPath hg19 (UCSC)NFRKB  -     chr11:129733670-129765490 -  11q24.3   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)NFRKB  -     11q24.3   [Description]    (hg38-Dec_2013)
EnsemblNFRKB - 11q24.3 [CytoView hg19]  NFRKB - 11q24.3 [CytoView hg38]
Mapping of homologs : NCBINFRKB [Mapview hg19]  NFRKB [Mapview hg38]
OMIM164013   
Gene and transcription
Genbank (Entrez)AL512730 BC063280 BM975529 DA324031 X80878
RefSeq transcript (Entrez)NM_001143835 NM_006165
RefSeq genomic (Entrez)NC_000011 NC_018922 NT_033899 NW_004929381
Consensus coding sequences : CCDS (NCBI)NFRKB
Cluster EST : UnigeneHs.530539 [ NCBI ]
CGAP (NCI)Hs.530539
Alternative Splicing GalleryENSG00000170322
Gene ExpressionNFRKB [ NCBI-GEO ]   NFRKB [ EBI - ARRAY_EXPRESS ]   NFRKB [ SEEK ]   NFRKB [ MEM ]
Gene Expression Viewer (FireBrowse)NFRKB [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)4798
GTEX Portal (Tissue expression)NFRKB
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ6P4R8   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ6P4R8  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ6P4R8
Splice isoforms : SwissVarQ6P4R8
PhosPhoSitePlusQ6P4R8
Domains : Interpro (EBI)NFRKB    NFRKB_winged_dom   
Domain families : Pfam (Sanger)NFRKB_winged (PF14465)   
Domain families : Pfam (NCBI)pfam14465   
Conserved Domain (NCBI)NFRKB
DMDM Disease mutations4798
Blocks (Seattle)NFRKB
PDB (SRS)3U21    4UF5    4UF6    4WLP   
PDB (PDBSum)3U21    4UF5    4UF6    4WLP   
PDB (IMB)3U21    4UF5    4UF6    4WLP   
PDB (RSDB)3U21    4UF5    4UF6    4WLP   
Structural Biology KnowledgeBase3U21    4UF5    4UF6    4WLP   
SCOP (Structural Classification of Proteins)3U21    4UF5    4UF6    4WLP   
CATH (Classification of proteins structures)3U21    4UF5    4UF6    4WLP   
SuperfamilyQ6P4R8
Human Protein AtlasENSG00000170322
Peptide AtlasQ6P4R8
HPRD01240
IPIIPI00472161   IPI00006171   IPI00479248   IPI00980532   IPI00979009   IPI00982852   IPI00978574   IPI00979821   IPI00982144   
Protein Interaction databases
DIP (DOE-UCLA)Q6P4R8
IntAct (EBI)Q6P4R8
FunCoupENSG00000170322
BioGRIDNFRKB
STRING (EMBL)NFRKB
ZODIACNFRKB
Ontologies - Pathways
QuickGOQ6P4R8
Ontology : AmiGOprotease binding  DNA binding  protein binding  nucleus  nucleoplasm  DNA repair  DNA recombination  regulation of transcription, DNA-templated  transcription from RNA polymerase II promoter  inflammatory response  Ino80 complex  Ino80 complex  
Ontology : EGO-EBIprotease binding  DNA binding  protein binding  nucleus  nucleoplasm  DNA repair  DNA recombination  regulation of transcription, DNA-templated  transcription from RNA polymerase II promoter  inflammatory response  Ino80 complex  Ino80 complex  
NDEx NetworkNFRKB
Atlas of Cancer Signalling NetworkNFRKB
Wikipedia pathwaysNFRKB
Orthology - Evolution
OrthoDB4798
GeneTree (enSembl)ENSG00000170322
Phylogenetic Trees/Animal Genes : TreeFamNFRKB
HOVERGENQ6P4R8
HOGENOMQ6P4R8
Homologs : HomoloGeneNFRKB
Homology/Alignments : Family Browser (UCSC)NFRKB
Gene fusions - Rearrangements
Fusion : MitelmanNFRKB/NOX4 [11q24.3/11q14.3]  
Fusion: TCGANFRKB 11q24.3 NOX4 11q14.3 BRCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerNFRKB [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)NFRKB
dbVarNFRKB
ClinVarNFRKB
1000_GenomesNFRKB 
Exome Variant ServerNFRKB
ExAC (Exome Aggregation Consortium)NFRKB (select the gene name)
Genetic variants : HAPMAP4798
Genomic Variants (DGV)NFRKB [DGVbeta]
DECIPHER (Syndromes)11:129733670-129765490  ENSG00000170322
CONAN: Copy Number AnalysisNFRKB 
Mutations
ICGC Data PortalNFRKB 
TCGA Data PortalNFRKB 
Broad Tumor PortalNFRKB
OASIS PortalNFRKB [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICNFRKB  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDNFRKB
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch NFRKB
DgiDB (Drug Gene Interaction Database)NFRKB
DoCM (Curated mutations)NFRKB (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)NFRKB (select a term)
intoGenNFRKB
Cancer3DNFRKB(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM164013   
Orphanet
MedgenNFRKB
Genetic Testing Registry NFRKB
NextProtQ6P4R8 [Medical]
TSGene4798
GENETestsNFRKB
Huge Navigator NFRKB [HugePedia]
snp3D : Map Gene to Disease4798
BioCentury BCIQNFRKB
ClinGenNFRKB
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD4798
Chemical/Pharm GKB GenePA31606
Clinical trialNFRKB
Miscellaneous
canSAR (ICR)NFRKB (select the gene name)
Probes
Litterature
PubMed39 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineNFRKB
EVEXNFRKB
GoPubMedNFRKB
iHOPNFRKB
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Mar 14 13:18:46 CET 2017

Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.