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NFU1 (NFU1 iron-sulfur cluster scaffold)

Identity

Alias_namesHIRIP5
HIRA interacting protein 5
NFU1 iron-sulfur cluster scaffold homolog (S. cerevisiae)
Alias_symbol (synonym)CGI-33
NifU
NIFUC
Other aliasHIRIP
MMDS1
Nfu
HGNC (Hugo) NFU1
LocusID (NCBI) 27247
Atlas_Id 70818
Location 2p13.3  [Link to chromosome band 2p13]
Location_base_pair Starts at 69623245 and ends at 69664760 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
DPYSL2 (8p21.2) / NFU1 (2p13.3)GFPT1 (2p13.3) / NFU1 (2p13.3)GRHL2 (8q22.3) / NFU1 (2p13.3)
NFU1 (2p13.3) / LYZ (12q15)NFU1 (2p13.3) / TRIM24 (7q33)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)NFU1   16287
Cards
Entrez_Gene (NCBI)NFU1  27247  NFU1 iron-sulfur cluster scaffold
AliasesCGI-33; HIRIP; HIRIP5; MMDS1; 
NIFUC; Nfu; NifU
GeneCards (Weizmann)NFU1
Ensembl hg19 (Hinxton)ENSG00000169599 [Gene_View]  chr2:69623245-69664760 [Contig_View]  NFU1 [Vega]
Ensembl hg38 (Hinxton)ENSG00000169599 [Gene_View]  chr2:69623245-69664760 [Contig_View]  NFU1 [Vega]
ICGC DataPortalENSG00000169599
TCGA cBioPortalNFU1
AceView (NCBI)NFU1
Genatlas (Paris)NFU1
WikiGenes27247
SOURCE (Princeton)NFU1
Genetics Home Reference (NIH)NFU1
Genomic and cartography
GoldenPath hg19 (UCSC)NFU1  -     chr2:69623245-69664760 -  2p13.3   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)NFU1  -     2p13.3   [Description]    (hg38-Dec_2013)
EnsemblNFU1 - 2p13.3 [CytoView hg19]  NFU1 - 2p13.3 [CytoView hg38]
Mapping of homologs : NCBINFU1 [Mapview hg19]  NFU1 [Mapview hg38]
OMIM605711   608100   
Gene and transcription
Genbank (Entrez)AA625581 AF132967 AI129426 AJ132584 AK300700
RefSeq transcript (Entrez)NM_001002755 NM_001002756 NM_001002757 NM_015700
RefSeq genomic (Entrez)NC_000002 NC_018913 NG_031931 NT_022184 NW_004929300
Consensus coding sequences : CCDS (NCBI)NFU1
Cluster EST : UnigeneHs.430439 [ NCBI ]
CGAP (NCI)Hs.430439
Alternative Splicing GalleryENSG00000169599
Gene ExpressionNFU1 [ NCBI-GEO ]   NFU1 [ EBI - ARRAY_EXPRESS ]   NFU1 [ SEEK ]   NFU1 [ MEM ]
Gene Expression Viewer (FireBrowse)NFU1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)27247
GTEX Portal (Tissue expression)NFU1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9UMS0   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9UMS0  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9UMS0
Splice isoforms : SwissVarQ9UMS0
PhosPhoSitePlusQ9UMS0
Domains : Interpro (EBI)Nfu/NifU_N    NFU1    NIF_FeS_clus_asmbl_NifU_C   
Domain families : Pfam (Sanger)Nfu_N (PF08712)    NifU (PF01106)   
Domain families : Pfam (NCBI)pfam08712    pfam01106   
Domain families : Smart (EMBL)Nfu_N (SM00932)  
Domain structure : Prodom (Prabi Lyon)NIF_FeS_clus_asmbl_NifU_C (PD002830)   
Conserved Domain (NCBI)NFU1
DMDM Disease mutations27247
Blocks (Seattle)NFU1
PDB (SRS)2LTM    2M5O   
PDB (PDBSum)2LTM    2M5O   
PDB (IMB)2LTM    2M5O   
PDB (RSDB)2LTM    2M5O   
Structural Biology KnowledgeBase2LTM    2M5O   
SCOP (Structural Classification of Proteins)2LTM    2M5O   
CATH (Classification of proteins structures)2LTM    2M5O   
SuperfamilyQ9UMS0
Human Protein AtlasENSG00000169599
Peptide AtlasQ9UMS0
HPRD12163
IPIIPI00455153   IPI00472265   IPI00160021   IPI00916223   IPI00915835   IPI00945634   IPI00953015   IPI00946044   
Protein Interaction databases
DIP (DOE-UCLA)Q9UMS0
IntAct (EBI)Q9UMS0
FunCoupENSG00000169599
BioGRIDNFU1
STRING (EMBL)NFU1
ZODIACNFU1
Ontologies - Pathways
QuickGOQ9UMS0
Ontology : AmiGOiron ion binding  protein binding  nucleus  nucleoplasm  cytoplasm  mitochondrion  cytosol  iron-sulfur cluster assembly  4 iron, 4 sulfur cluster binding  
Ontology : EGO-EBIiron ion binding  protein binding  nucleus  nucleoplasm  cytoplasm  mitochondrion  cytosol  iron-sulfur cluster assembly  4 iron, 4 sulfur cluster binding  
NDEx NetworkNFU1
Atlas of Cancer Signalling NetworkNFU1
Wikipedia pathwaysNFU1
Orthology - Evolution
OrthoDB27247
GeneTree (enSembl)ENSG00000169599
Phylogenetic Trees/Animal Genes : TreeFamNFU1
HOVERGENQ9UMS0
HOGENOMQ9UMS0
Homologs : HomoloGeneNFU1
Homology/Alignments : Family Browser (UCSC)NFU1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerNFU1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)NFU1
dbVarNFU1
ClinVarNFU1
1000_GenomesNFU1 
Exome Variant ServerNFU1
ExAC (Exome Aggregation Consortium)NFU1 (select the gene name)
Genetic variants : HAPMAP27247
Genomic Variants (DGV)NFU1 [DGVbeta]
DECIPHER (Syndromes)2:69623245-69664760  ENSG00000169599
CONAN: Copy Number AnalysisNFU1 
Mutations
ICGC Data PortalNFU1 
TCGA Data PortalNFU1 
Broad Tumor PortalNFU1
OASIS PortalNFU1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICNFU1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDNFU1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch NFU1
DgiDB (Drug Gene Interaction Database)NFU1
DoCM (Curated mutations)NFU1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)NFU1 (select a term)
intoGenNFU1
Cancer3DNFU1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM605711    608100   
Orphanet22845   
MedgenNFU1
Genetic Testing Registry NFU1
NextProtQ9UMS0 [Medical]
TSGene27247
GENETestsNFU1
Huge Navigator NFU1 [HugePedia]
snp3D : Map Gene to Disease27247
BioCentury BCIQNFU1
ClinGenNFU1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD27247
Chemical/Pharm GKB GenePA162397454
Clinical trialNFU1
Miscellaneous
canSAR (ICR)NFU1 (select the gene name)
Probes
Litterature
PubMed17 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineNFU1
EVEXNFU1
GoPubMedNFU1
iHOPNFU1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 12:34:53 CET 2017

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