| ABHD2 (15q26.1) / NFX1 (9p13.3) | B4GALT1 (9p21.1) / NFX1 (9p13.3) | CRLS1 (20p12.3) / NFX1 (9p13.3) |
|
FN1 (2q35) / NFX1 (9p13.3) | GALNT1 (18q12.2) / NFX1 (9p13.3) | NFX1 (9p13.3) / ACO1 (9p21.1) |
|
NFX1 (9p13.3) / ARHGEF39 (9p13.3) | NFX1 (9p13.3) / BAG1 (9p13.3) | NFX1 (9p13.3) / C11orf80 (11q13.2) |
|
NFX1 (9p13.3) / C9orf24 (9p13.3) | NFX1 (9p13.3) / DAAM1 (14q23.1) | NFX1 (9p13.3) / NFX1 (9p13.3) |
|
NFX1 (9p13.3) / SPINK4 (9p13.3) | NFX1 (9p13.3) / TMEM8B (9p13.3) | NFX1 (9p13.3) / ZNF616 (19q13.41) |
|
ZNF600 (19q13.41) / NFX1 (9p13.3) | B4GALT1 9p21.1 / NFX1 9p13.3 | CRLS1 20p12.3 / NFX1 9p13.3 |
|
NFX1 9p13.3 / ACO1 9p21.1 | NFX1 9p13.3 C9orf100 | NFX1 9p13.3 / C9orf24 9p13.3 |
|
NFX1 9p13.3 / SPINK4 9p13.3 | NFX1 9p13.3 / TMEM8B 9p13.3 | NFX1 9p13.3 / ZNF616 19q13.41 |
|
ZNF600 19q13.41 / NFX1 9p13.3 |
| Nomenclature |
HGNC (Hugo) | NFX1 7803 |
| Cards |
Entrez_Gene (NCBI) | NFX1 nuclear transcription factor, X-box binding 1 |
Aliases | NFX2; TEG-42; Tex42 |
GeneCards (Weizmann) | NFX1 |
Ensembl hg19 (Hinxton) | ENSG00000086102 [Gene_View] |
Ensembl hg38 (Hinxton) | ENSG00000086102 [Gene_View]  ENSG00000086102 [Sequence] chr9:33290516-33348731 [Contig_View] NFX1 [Vega] |
ICGC DataPortal | ENSG00000086102 |
TCGA cBioPortal | NFX1 |
AceView (NCBI) | NFX1 |
Genatlas (Paris) | NFX1 |
SOURCE (Princeton) | NFX1 |
Genetics Home Reference (NIH) | NFX1 |
| Genomic and cartography |
GoldenPath hg38 (UCSC) | NFX1 - chr9:33290516-33348731 + 9p13.3 [Description] (hg38-Dec_2013) |
GoldenPath hg19 (UCSC) | NFX1 - 9p13.3 [Description] (hg19-Feb_2009) |
GoldenPath | NFX1 - 9p13.3 [CytoView hg19] NFX1 - 9p13.3 [CytoView hg38] |
ImmunoBase | ENSG00000086102 |
genome Data Viewer NCBI | NFX1 [Mapview hg19] |
OMIM | 603255 |
| Gene and transcription |
Genbank (Entrez) | AF332009 AI679589 AI884552 AK055847 AK225750 |
RefSeq transcript (Entrez) | NM_001318758 NM_002504 NM_147133 NM_147134 |
RefSeq genomic (Entrez) | |
Consensus coding sequences : CCDS (NCBI) | NFX1 |
Alternative Splicing Gallery | ENSG00000086102 |
Gene Expression | NFX1 [ NCBI-GEO ] NFX1 [ EBI - ARRAY_EXPRESS ]
NFX1 [ SEEK ] NFX1 [ MEM ] |
Gene Expression Viewer (FireBrowse) | NFX1 [ Firebrowse - Broad ] |
Genevisible | Expression of NFX1 in : [tissues]  [cell-lines]  [cancer]  [perturbations]   |
BioGPS (Tissue expression) | 4799 |
GTEX Portal (Tissue expression) | NFX1 |
Human Protein Atlas | ENSG00000086102-NFX1 [pathology] [cell] [tissue] |
| Protein : pattern, domain, 3D structure |
UniProt/SwissProt | Q12986 [function] [subcellular_location] [family_and_domains] [pathology_and_biotech] [ptm_processing] [expression] [interaction] |
NextProt | Q12986 [Sequence] [Exons] [Medical] [Publications] |
With graphics : InterPro | Q12986 |
Splice isoforms : SwissVar | Q12986 |
Catalytic activity : Enzyme | 2.3.2.- [ Enzyme-Expasy ] 2.3.2.-2.3.2.- [ IntEnz-EBI ] 2.3.2.- [ BRENDA ] 2.3.2.- [ KEGG ] [ MEROPS ] |
PhosPhoSitePlus | Q12986 |
Domaine pattern : Prosite (Expaxy) | R3H (PS51061) ZF_RING_2 (PS50089) |
Domains : Interpro (EBI) | NFX1_fam R3H_dom R3H_dom_sf R3H_NF-X1 Zinc_finger_PHD-type_CS Znf_NFX1 Znf_PHD-finger Znf_RING |
Domain families : Pfam (Sanger) | R3H (PF01424) zf-NF-X1 (PF01422) |
Domain families : Pfam (NCBI) | pfam01424 pfam01422 |
Domain families : Smart (EMBL) | R3H (SM00393) RING (SM00184) ZnF_NFX (SM00438) |
Conserved Domain (NCBI) | NFX1 |
Blocks (Seattle) | NFX1 |
Superfamily | Q12986 |
Human Protein Atlas [tissue] | ENSG00000086102-NFX1 [tissue] |
Peptide Atlas | Q12986 |
HPRD | 11936 |
IPI | IPI00843917 IPI00158157 IPI00158159 IPI00030404 IPI01010052 |
| Protein Interaction databases |
DIP (DOE-UCLA) | Q12986 |
IntAct (EBI) | Q12986 |
BioGRID | NFX1 |
STRING (EMBL) | NFX1 |
ZODIAC | NFX1 |
| Ontologies - Pathways |
QuickGO | Q12986 |
Ontology : AmiGO | negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II nuclear chromatin RNA polymerase II regulatory region sequence-specific DNA binding RNA polymerase II regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription repressor activity, RNA polymerase II-specific RNA binding nucleus nucleoplasm nucleolus cytosol plasma membrane regulation of transcription, DNA-templated transcription by RNA polymerase II inflammatory response zinc ion binding viral process protein ubiquitination negative regulation of MHC class II biosynthetic process protein autoubiquitination ubiquitin protein ligase activity ubiquitin protein ligase activity |
Ontology : EGO-EBI | negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II nuclear chromatin RNA polymerase II regulatory region sequence-specific DNA binding RNA polymerase II regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription repressor activity, RNA polymerase II-specific RNA binding nucleus nucleoplasm nucleolus cytosol plasma membrane regulation of transcription, DNA-templated transcription by RNA polymerase II inflammatory response zinc ion binding viral process protein ubiquitination negative regulation of MHC class II biosynthetic process protein autoubiquitination ubiquitin protein ligase activity ubiquitin protein ligase activity |
NDEx Network | NFX1 |
Atlas of Cancer Signalling Network | NFX1 |
Wikipedia pathways | NFX1 |
| Orthology - Evolution |
OrthoDB | 4799 |
GeneTree (enSembl) | ENSG00000086102 |
Phylogenetic Trees/Animal Genes : TreeFam | NFX1 |
HOGENOM | Q12986 |
Homologs : HomoloGene | NFX1 |
Homology/Alignments : Family Browser (UCSC) | NFX1 |
| Gene fusions - Rearrangements |
Fusion : Mitelman | B4GALT1/NFX1 [9p21.1/9p13.3]   |
Fusion : Mitelman | CRLS1/NFX1 [20p12.3/9p13.3]   |
Fusion : Mitelman | NFX1/ACO1 [9p13.3/9p21.1]   |
Fusion : Mitelman | NFX1/ARHGEF39 [9p13.3/9p13.3]   |
Fusion : Mitelman | NFX1/C9orf24 [9p13.3/9p13.3]   |
Fusion : Mitelman | NFX1/SPINK4 [9p13.3/9p13.3]   |
Fusion : Mitelman | NFX1/TMEM8B [9p13.3/9p13.3]   |
Fusion : Mitelman | NFX1/ZNF616 [9p13.3/19q13.41]   |
Fusion : Mitelman | ZNF600/NFX1 [19q13.41/9p13.3]   |
Fusion Portal | B4GALT1 9p21.1 NFX1 9p13.3 BRCA |
Fusion Portal | CRLS1 20p12.3 NFX1 9p13.3 KIRC |
Fusion Portal | NFX1 9p13.3 ACO1 9p21.1 LUSC |
Fusion Portal | NFX1 9p13.3 C9orf100 HNSC |
Fusion Portal | NFX1 9p13.3 C9orf24 9p13.3 GBM |
Fusion Portal | NFX1 9p13.3 SPINK4 9p13.3 BRCA |
Fusion Portal | NFX1 9p13.3 TMEM8B 9p13.3 LUSC |
Fusion Portal | NFX1 9p13.3 ZNF616 19q13.41 BRCA |
Fusion Portal | ZNF600 19q13.41 NFX1 9p13.3 BRCA |
Fusion Cancer (Beijing) | FN1 [2q35] - NFX1 [9p13.3] [FUSC003438] |
Fusion : Quiver | NFX1 |
| Polymorphisms : SNP and Copy number variants |
NCBI Variation Viewer | NFX1 [hg38] |
dbVar | NFX1 |
ClinVar | NFX1 |
Monarch | NFX1 |
1000_Genomes | NFX1 |
Exome Variant Server | NFX1 |
GNOMAD Browser | ENSG00000086102 |
Varsome Browser | NFX1 |
Genomic Variants (DGV) | NFX1 [DGVbeta] |
DECIPHER | NFX1 [patients] [syndromes] [variants] [genes] |
CONAN: Copy Number Analysis | NFX1 |
| Mutations |
ICGC Data Portal | NFX1 |
TCGA Data Portal | NFX1 |
Broad Tumor Portal | NFX1 |
OASIS Portal | NFX1 [ Somatic mutations - Copy number] |
Somatic Mutations in Cancer : COSMIC | NFX1 [overview] [genome browser] [tissue] [distribution] |
Somatic Mutations in Cancer : COSMIC3D | NFX1 |
Mutations and Diseases : HGMD | NFX1 |
LOVD (Leiden Open Variation Database) | Whole genome datasets |
LOVD (Leiden Open Variation Database) | LOVD - Leiden Open Variation Database |
LOVD (Leiden Open Variation Database) | LOVD 3.0 shared installation |
BioMuta | search NFX1 |
DgiDB (Drug Gene Interaction Database) | NFX1 |
DoCM (Curated mutations) | NFX1 (select the gene name) |
CIViC (Clinical Interpretations of Variants in Cancer) | NFX1 (select a term) |
intoGen | NFX1 |
Cancer3D | NFX1(select the gene name) |
Impact of mutations | [PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser] |
| Diseases |
---|
OMIM | 603255 |
Orphanet | |
DisGeNET | NFX1 |
Medgen | NFX1 |
Genetic Testing Registry | NFX1
|
NextProt | Q12986 [Medical] |
GENETests | NFX1 |
Target Validation | NFX1 |
Huge Navigator |
NFX1 [HugePedia] |
ClinGen | NFX1 |
| Clinical trials, drugs, therapy |
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MyCancerGenome | NFX1 |
Protein Interactions : CTD | |
Pharm GKB Gene | PA31608 |
Pharos | Q12986 |
Clinical trial | NFX1 |
| Miscellaneous |
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canSAR (ICR) | NFX1 (select the gene name) |
Harmonizome | NFX1 |
DataMed Index | NFX1 |
| Probes |
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| Litterature |
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PubMed | 40 Pubmed reference(s) in Entrez |
GeneRIFs | Gene References Into Functions (Entrez) |
EVEX | NFX1 |