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NFXL1 (nuclear transcription factor, X-box binding like 1)

Identity

Alias (NCBI)CDZFP
HOZFP
OZFP
URCC5
HGNC (Hugo) NFXL1
HGNC Alias symbHOZFP
HGNC Alias nameovarian zinc finger protein
LocusID (NCBI) 152518
Atlas_Id 70819
Location 4p12  [Link to chromosome band 4p12]
Location_base_pair Starts at 47847233 and ends at 47914644 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
DTX3L (3q21.1) / NFXL1 (4p12)NFXL1 (4p12) / RACK1 (5q35.3)OCIAD2 (4p11) / NFXL1 (4p12)
RACK1 (5q35.3) / NFXL1 (4p12)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)NFXL1   18726
Cards
Entrez_Gene (NCBI)NFXL1    nuclear transcription factor, X-box binding like 1
AliasesCDZFP; HOZFP; OZFP; URCC5
GeneCards (Weizmann)NFXL1
Ensembl hg19 (Hinxton)ENSG00000170448 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000170448 [Gene_View]  ENSG00000170448 [Sequence]  chr4:47847233-47914644 [Contig_View]  NFXL1 [Vega]
ICGC DataPortalENSG00000170448
TCGA cBioPortalNFXL1
AceView (NCBI)NFXL1
Genatlas (Paris)NFXL1
SOURCE (Princeton)NFXL1
Genetics Home Reference (NIH)NFXL1
Genomic and cartography
GoldenPath hg38 (UCSC)NFXL1  -     chr4:47847233-47914644 -  4p12   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)NFXL1  -     4p12   [Description]    (hg19-Feb_2009)
GoldenPathNFXL1 - 4p12 [CytoView hg19]  NFXL1 - 4p12 [CytoView hg38]
ImmunoBaseENSG00000170448
Genome Data Viewer NCBINFXL1 [Mapview hg19]  
Gene and transcription
Genbank (Entrez)AB085695 AB181916 AK131285 AK302440 AY134856
RefSeq transcript (Entrez)NM_001278623 NM_001278624 NM_152995
Consensus coding sequences : CCDS (NCBI)NFXL1
Gene ExpressionNFXL1 [ NCBI-GEO ]   NFXL1 [ EBI - ARRAY_EXPRESS ]   NFXL1 [ SEEK ]   NFXL1 [ MEM ]
Gene Expression Viewer (FireBrowse)NFXL1 [ Firebrowse - Broad ]
GenevisibleExpression of NFXL1 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)152518
GTEX Portal (Tissue expression)NFXL1
Human Protein AtlasENSG00000170448-NFXL1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ6ZNB6   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ6ZNB6  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ6ZNB6
PhosPhoSitePlusQ6ZNB6
Domaine pattern : Prosite (Expaxy)ZF_RING_2 (PS50089)   
Domains : Interpro (EBI)NFX1_fam    Zinc_finger_PHD-type_CS    Znf_NFX1    Znf_RING   
Domain families : Pfam (Sanger)zf-NF-X1 (PF01422)   
Domain families : Pfam (NCBI)pfam01422   
Domain families : Smart (EMBL)ZnF_NFX (SM00438)  
Conserved Domain (NCBI)NFXL1
SuperfamilyQ6ZNB6
AlphaFold pdb e-kbQ6ZNB6   
Human Protein Atlas [tissue]ENSG00000170448-NFXL1 [tissue]
HPRD11025
Protein Interaction databases
DIP (DOE-UCLA)Q6ZNB6
IntAct (EBI)Q6ZNB6
BioGRIDNFXL1
STRING (EMBL)NFXL1
ZODIACNFXL1
Ontologies - Pathways
QuickGOQ6ZNB6
Ontology : AmiGOchromatin  RNA polymerase II transcription regulatory region sequence-specific DNA binding  DNA-binding transcription factor activity, RNA polymerase II-specific  nucleus  regulation of transcription, DNA-templated  regulation of transcription by RNA polymerase II  zinc ion binding  membrane  integral component of membrane  
Ontology : EGO-EBIchromatin  RNA polymerase II transcription regulatory region sequence-specific DNA binding  DNA-binding transcription factor activity, RNA polymerase II-specific  nucleus  regulation of transcription, DNA-templated  regulation of transcription by RNA polymerase II  zinc ion binding  membrane  integral component of membrane  
NDEx NetworkNFXL1
Atlas of Cancer Signalling NetworkNFXL1
Wikipedia pathwaysNFXL1
Orthology - Evolution
OrthoDB152518
GeneTree (enSembl)ENSG00000170448
Phylogenetic Trees/Animal Genes : TreeFamNFXL1
Homologs : HomoloGeneNFXL1
Homology/Alignments : Family Browser (UCSC)NFXL1
Gene fusions - Rearrangements
Fusion : QuiverNFXL1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerNFXL1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)NFXL1
dbVarNFXL1
ClinVarNFXL1
MonarchNFXL1
1000_GenomesNFXL1 
Exome Variant ServerNFXL1
GNOMAD BrowserENSG00000170448
Varsome BrowserNFXL1
ACMGNFXL1 variants
VarityQ6ZNB6
Genomic Variants (DGV)NFXL1 [DGVbeta]
DECIPHERNFXL1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisNFXL1 
Mutations
ICGC Data PortalNFXL1 
TCGA Data PortalNFXL1 
Broad Tumor PortalNFXL1
OASIS PortalNFXL1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICNFXL1  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DNFXL1
Mutations and Diseases : HGMDNFXL1
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaNFXL1
DgiDB (Drug Gene Interaction Database)NFXL1
DoCM (Curated mutations)NFXL1
CIViC (Clinical Interpretations of Variants in Cancer)NFXL1
Cancer3DNFXL1
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
DisGeNETNFXL1
MedgenNFXL1
Genetic Testing Registry NFXL1
NextProtQ6ZNB6 [Medical]
GENETestsNFXL1
Target ValidationNFXL1
Huge Navigator NFXL1 [HugePedia]
ClinGenNFXL1
Clinical trials, drugs, therapy
MyCancerGenomeNFXL1
Protein Interactions : CTDNFXL1
Pharm GKB GenePA38661
PharosQ6ZNB6
Clinical trialNFXL1
Miscellaneous
canSAR (ICR)NFXL1
HarmonizomeNFXL1
DataMed IndexNFXL1
Probes
Litterature
PubMed36 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXNFXL1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 16:12:41 CEST 2021

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