Atlas of Genetics and Cytogenetics in Oncology and Haematology


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NFYA (nuclear transcription factor Y subunit alpha)

Identity

Alias_namesnuclear transcription factor Y
Alias_symbol (synonym)HAP2
CBF-B
NF-YA
Other aliasCBF-A
HGNC (Hugo) NFYA
LocusID (NCBI) 4800
Atlas_Id 45601
Location 6p21.1  [Link to chromosome band 6p21]
Location_base_pair Starts at 41072968 and ends at 41102407 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
CSH1 (17q23.3) / NFYA (6p21.1)LGALS4 (19q13.2) / NFYA (6p21.1)NFYA (6p21.1) / ADCY10P1 ()
NFYA (6p21.1) / FKBP1AP1 (19q13.43)NFYA (6p21.1) / ZFP36L2 (2p21)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)NFYA   7804
Cards
Entrez_Gene (NCBI)NFYA  4800  nuclear transcription factor Y subunit alpha
AliasesCBF-A; CBF-B; HAP2; NF-YA
GeneCards (Weizmann)NFYA
Ensembl hg19 (Hinxton)ENSG00000001167 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000001167 [Gene_View]  ENSG00000001167 [Sequence]  chr6:41072968-41102407 [Contig_View]  NFYA [Vega]
ICGC DataPortalENSG00000001167
TCGA cBioPortalNFYA
AceView (NCBI)NFYA
Genatlas (Paris)NFYA
WikiGenes4800
SOURCE (Princeton)NFYA
Genetics Home Reference (NIH)NFYA
Genomic and cartography
GoldenPath hg38 (UCSC)NFYA  -     chr6:41072968-41102407 +  6p21.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)NFYA  -     6p21.1   [Description]    (hg19-Feb_2009)
EnsemblNFYA - 6p21.1 [CytoView hg19]  NFYA - 6p21.1 [CytoView hg38]
Mapping of homologs : NCBINFYA [Mapview hg19]  NFYA [Mapview hg38]
OMIM189903   
Gene and transcription
Genbank (Entrez)AA905268 AJ420494 AK002098 AK025201 BC026923
RefSeq transcript (Entrez)NM_002505 NM_021705
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)NFYA
Cluster EST : UnigeneHs.10441 [ NCBI ]
CGAP (NCI)Hs.10441
Alternative Splicing GalleryENSG00000001167
Gene ExpressionNFYA [ NCBI-GEO ]   NFYA [ EBI - ARRAY_EXPRESS ]   NFYA [ SEEK ]   NFYA [ MEM ]
Gene Expression Viewer (FireBrowse)NFYA [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)4800
GTEX Portal (Tissue expression)NFYA
Human Protein AtlasENSG00000001167-NFYA [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP23511   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP23511  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP23511
Splice isoforms : SwissVarP23511
PhosPhoSitePlusP23511
Domaine pattern : Prosite (Expaxy)NFYA_HAP2_1 (PS00686)    NFYA_HAP2_2 (PS51152)   
Domains : Interpro (EBI)CCAAT-binding_factor_CS    NFYA   
Domain families : Pfam (Sanger)CBFB_NFYA (PF02045)   
Domain families : Pfam (NCBI)pfam02045   
Domain families : Smart (EMBL)CBF (SM00521)  
Conserved Domain (NCBI)NFYA
DMDM Disease mutations4800
Blocks (Seattle)NFYA
PDB (SRS)4AWL   
PDB (PDBSum)4AWL   
PDB (IMB)4AWL   
PDB (RSDB)4AWL   
Structural Biology KnowledgeBase4AWL   
SCOP (Structural Classification of Proteins)4AWL   
CATH (Classification of proteins structures)4AWL   
SuperfamilyP23511
Human Protein Atlas [tissue]ENSG00000001167-NFYA [tissue]
Peptide AtlasP23511
HPRD01793
IPIIPI00333568   IPI00218470   
Protein Interaction databases
DIP (DOE-UCLA)P23511
IntAct (EBI)P23511
FunCoupENSG00000001167
BioGRIDNFYA
STRING (EMBL)NFYA
ZODIACNFYA
Ontologies - Pathways
QuickGOP23511
Ontology : AmiGORNA polymerase II proximal promoter sequence-specific DNA binding  RNA polymerase II distal enhancer sequence-specific DNA binding  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA binding  DNA-binding transcription factor activity  protein binding  nucleus  nucleoplasm  nucleoplasm  regulation of transcription, DNA-templated  regulation of transcription by RNA polymerase II  transcription by RNA polymerase II  CCAAT-binding factor complex  protein-DNA complex  transcription regulatory region DNA binding  regulation of cholesterol biosynthetic process  positive regulation of transcription, DNA-templated  rhythmic process  RNA polymerase II transcription factor complex  
Ontology : EGO-EBIRNA polymerase II proximal promoter sequence-specific DNA binding  RNA polymerase II distal enhancer sequence-specific DNA binding  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA binding  DNA-binding transcription factor activity  protein binding  nucleus  nucleoplasm  nucleoplasm  regulation of transcription, DNA-templated  regulation of transcription by RNA polymerase II  transcription by RNA polymerase II  CCAAT-binding factor complex  protein-DNA complex  transcription regulatory region DNA binding  regulation of cholesterol biosynthetic process  positive regulation of transcription, DNA-templated  rhythmic process  RNA polymerase II transcription factor complex  
Pathways : KEGGAntigen processing and presentation    Tuberculosis   
NDEx NetworkNFYA
Atlas of Cancer Signalling NetworkNFYA
Wikipedia pathwaysNFYA
Orthology - Evolution
OrthoDB4800
GeneTree (enSembl)ENSG00000001167
Phylogenetic Trees/Animal Genes : TreeFamNFYA
HOVERGENP23511
HOGENOMP23511
Homologs : HomoloGeneNFYA
Homology/Alignments : Family Browser (UCSC)NFYA
Gene fusions - Rearrangements
Fusion Cancer (Beijing)NFYA [6p21.1]  -  FKBP1AP1 [19q13.43]  [FUSC004256]
Fusion : QuiverNFYA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerNFYA [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)NFYA
dbVarNFYA
ClinVarNFYA
1000_GenomesNFYA 
Exome Variant ServerNFYA
ExAC (Exome Aggregation Consortium)ENSG00000001167
GNOMAD BrowserENSG00000001167
Varsome BrowserNFYA
Genetic variants : HAPMAP4800
Genomic Variants (DGV)NFYA [DGVbeta]
DECIPHERNFYA [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisNFYA 
Mutations
ICGC Data PortalNFYA 
TCGA Data PortalNFYA 
Broad Tumor PortalNFYA
OASIS PortalNFYA [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICNFYA  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDNFYA
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch NFYA
DgiDB (Drug Gene Interaction Database)NFYA
DoCM (Curated mutations)NFYA (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)NFYA (select a term)
intoGenNFYA
Cancer3DNFYA(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM189903   
Orphanet
DisGeNETNFYA
MedgenNFYA
Genetic Testing Registry NFYA
NextProtP23511 [Medical]
TSGene4800
GENETestsNFYA
Target ValidationNFYA
Huge Navigator NFYA [HugePedia]
snp3D : Map Gene to Disease4800
BioCentury BCIQNFYA
ClinGenNFYA
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD4800
Chemical/Pharm GKB GenePA31609
Clinical trialNFYA
Miscellaneous
canSAR (ICR)NFYA (select the gene name)
Probes
Litterature
PubMed108 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineNFYA
EVEXNFYA
GoPubMedNFYA
iHOPNFYA
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Nov 6 11:26:07 CET 2018

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