| Nomenclature |
|---|
| HGNC (Hugo) | NFYA 7804 |
| Cards |
|---|
| Entrez_Gene (NCBI) | NFYA nuclear transcription factor Y subunit alpha |
| Aliases | CBF-A; CBF-B; HAP2; NF-YA |
| GeneCards (Weizmann) | NFYA |
| Ensembl hg19 (Hinxton) | ENSG00000001167 [Gene_View] |
| Ensembl hg38 (Hinxton) | ENSG00000001167 [Gene_View] ENSG00000001167 [Sequence] chr6:41072974-41102403 [Contig_View] NFYA [Vega] |
| ICGC DataPortal | ENSG00000001167 |
| TCGA cBioPortal | NFYA |
| AceView (NCBI) | NFYA |
| Genatlas (Paris) | NFYA |
| SOURCE (Princeton) | NFYA |
| Genetics Home Reference (NIH) | NFYA |
| Genomic and cartography |
|---|
| GoldenPath hg38 (UCSC) | NFYA - chr6:41072974-41102403 + 6p21.1 [Description] (hg38-Dec_2013) |
| GoldenPath hg19 (UCSC) | NFYA - 6p21.1 [Description] (hg19-Feb_2009) |
| GoldenPath | NFYA - 6p21.1 [CytoView hg19] NFYA - 6p21.1 [CytoView hg38] |
| ImmunoBase | ENSG00000001167 |
| genome Data Viewer NCBI | NFYA [Mapview hg19] |
| OMIM | 189903 |
| Gene and transcription |
|---|
| Genbank (Entrez) | AA905268 AJ420494 AK002098 AK025201 BC026923 |
| RefSeq transcript (Entrez) | NM_002505 NM_021705 |
| RefSeq genomic (Entrez) | |
| Consensus coding sequences : CCDS (NCBI) | NFYA |
| Alternative Splicing Gallery | ENSG00000001167 |
| Gene Expression | NFYA [ NCBI-GEO ] NFYA [ EBI - ARRAY_EXPRESS ]
NFYA [ SEEK ] NFYA [ MEM ] |
| Gene Expression Viewer (FireBrowse) | NFYA [ Firebrowse - Broad ] |
| Genevisible | Expression of NFYA in : [tissues] [cell-lines] [cancer] [perturbations] |
| BioGPS (Tissue expression) | 4800 |
| GTEX Portal (Tissue expression) | NFYA |
| Human Protein Atlas | ENSG00000001167-NFYA [pathology] [cell] [tissue] |
| Protein : pattern, domain, 3D structure |
|---|
| UniProt/SwissProt | P23511 [function] [subcellular_location] [family_and_domains] [pathology_and_biotech] [ptm_processing] [expression] [interaction] |
| NextProt | P23511 [Sequence] [Exons] [Medical] [Publications] |
| With graphics : InterPro | P23511 |
| Splice isoforms : SwissVar | P23511 |
| PhosPhoSitePlus | P23511 |
| Domaine pattern : Prosite (Expaxy) | NFYA_HAP2_1 (PS00686) NFYA_HAP2_2 (PS51152) |
| Domains : Interpro (EBI) | CCAAT-binding_factor_CS NFYA |
| Domain families : Pfam (Sanger) | CBFB_NFYA (PF02045) |
| Domain families : Pfam (NCBI) | pfam02045 |
| Domain families : Smart (EMBL) | CBF (SM00521) |
| Conserved Domain (NCBI) | NFYA |
| Blocks (Seattle) | NFYA |
| PDB (RSDB) | 4AWL 6QMP 6QMQ 6QMS |
| PDB Europe | 4AWL 6QMP 6QMQ 6QMS |
| PDB (PDBSum) | 4AWL 6QMP 6QMQ 6QMS |
| PDB (IMB) | 4AWL 6QMP 6QMQ 6QMS |
| Structural Biology KnowledgeBase | 4AWL 6QMP 6QMQ 6QMS |
| SCOP (Structural Classification of Proteins) | 4AWL 6QMP 6QMQ 6QMS |
| CATH (Classification of proteins structures) | 4AWL 6QMP 6QMQ 6QMS |
| Superfamily | P23511 |
| Human Protein Atlas [tissue] | ENSG00000001167-NFYA [tissue] |
| Peptide Atlas | P23511 |
| HPRD | 01793 |
| IPI | IPI00333568 IPI00218470 |
| Protein Interaction databases |
|---|
| DIP (DOE-UCLA) | P23511 |
| IntAct (EBI) | P23511 |
| BioGRID | NFYA |
| STRING (EMBL) | NFYA |
| ZODIAC | NFYA |
| Ontologies - Pathways |
|---|
| QuickGO | P23511 |
| Ontology : AmiGO | nuclear chromatin transcription regulatory region sequence-specific DNA binding RNA polymerase II proximal promoter sequence-specific DNA binding RNA polymerase II proximal promoter sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific DNA binding DNA-binding transcription factor activity protein binding nucleus nucleus nucleoplasm nucleoplasm regulation of transcription, DNA-templated regulation of transcription, DNA-templated transcription by RNA polymerase II positive regulation of transcription from RNA polymerase II promoter in response to iron CCAAT-binding factor complex CCAAT-binding factor complex protein-DNA complex regulation of cholesterol biosynthetic process positive regulation of transcription, DNA-templated rhythmic process RNA polymerase II transcription factor complex |
| Ontology : EGO-EBI | nuclear chromatin transcription regulatory region sequence-specific DNA binding RNA polymerase II proximal promoter sequence-specific DNA binding RNA polymerase II proximal promoter sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific DNA binding DNA-binding transcription factor activity protein binding nucleus nucleus nucleoplasm nucleoplasm regulation of transcription, DNA-templated regulation of transcription, DNA-templated transcription by RNA polymerase II positive regulation of transcription from RNA polymerase II promoter in response to iron CCAAT-binding factor complex CCAAT-binding factor complex protein-DNA complex regulation of cholesterol biosynthetic process positive regulation of transcription, DNA-templated rhythmic process RNA polymerase II transcription factor complex |
| Pathways : KEGG | Antigen processing and presentation Tuberculosis |
| NDEx Network | NFYA |
| Atlas of Cancer Signalling Network | NFYA |
| Wikipedia pathways | NFYA |
| Orthology - Evolution |
|---|
| OrthoDB | 4800 |
| GeneTree (enSembl) | ENSG00000001167 |
| Phylogenetic Trees/Animal Genes : TreeFam | NFYA |
| HOGENOM | P23511 |
| Homologs : HomoloGene | NFYA |
| Homology/Alignments : Family Browser (UCSC) | NFYA |
| Gene fusions - Rearrangements |
|---|
| Fusion Cancer (Beijing) | NFYA [6p21.1] - FKBP1AP1 [19q13.43] [FUSC004256] |
| Fusion : Quiver | NFYA |
| Polymorphisms : SNP and Copy number variants |
|---|
| NCBI Variation Viewer | NFYA [hg38] |
| dbVar | NFYA |
| ClinVar | NFYA |
| Monarch | NFYA |
| 1000_Genomes | NFYA |
| Exome Variant Server | NFYA |
| GNOMAD Browser | ENSG00000001167 |
| Varsome Browser | NFYA |
| Genomic Variants (DGV) | NFYA [DGVbeta] |
| DECIPHER | NFYA [patients] [syndromes] [variants] [genes] |
| CONAN: Copy Number Analysis | NFYA |
| Mutations |
|---|
| ICGC Data Portal | NFYA |
| TCGA Data Portal | NFYA |
| Broad Tumor Portal | NFYA |
| OASIS Portal | NFYA [ Somatic mutations - Copy number] |
| Somatic Mutations in Cancer : COSMIC | NFYA [overview] [genome browser] [tissue] [distribution] |
| Somatic Mutations in Cancer : COSMIC3D | NFYA |
| Mutations and Diseases : HGMD | NFYA |
| LOVD (Leiden Open Variation Database) | Whole genome datasets |
| LOVD (Leiden Open Variation Database) | LOVD - Leiden Open Variation Database |
| LOVD (Leiden Open Variation Database) | LOVD 3.0 shared installation |
| BioMuta | search NFYA |
| DgiDB (Drug Gene Interaction Database) | NFYA |
| DoCM (Curated mutations) | NFYA (select the gene name) |
| CIViC (Clinical Interpretations of Variants in Cancer) | NFYA (select a term) |
| intoGen | NFYA |
| Cancer3D | NFYA(select the gene name) |
| Impact of mutations | [PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser] |
| Diseases |
|---|
| OMIM | 189903 |
| Orphanet | |
| DisGeNET | NFYA |
| Medgen | NFYA |
| Genetic Testing Registry | NFYA
|
| NextProt | P23511 [Medical] |
| GENETests | NFYA |
| Target Validation | NFYA |
| Huge Navigator |
NFYA [HugePedia] |
| ClinGen | NFYA |
| Clinical trials, drugs, therapy |
|---|
| MyCancerGenome | NFYA |
| Protein Interactions : CTD | |
| Pharm GKB Gene | PA31609 |
| Pharos | P23511 |
| Clinical trial | NFYA |
| Miscellaneous |
|---|
| canSAR (ICR) | NFYA (select the gene name) |
| Harmonizome | NFYA |
| DataMed Index | NFYA |
| Probes |
|---|
| Litterature |
|---|
| PubMed | 122 Pubmed reference(s) in Entrez |
| GeneRIFs | Gene References Into Functions (Entrez) |
| EVEX | NFYA |
