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NFYB (nuclear transcription factor Y subunit beta)

Identity

Alias (NCBI)CBF-A
CBF-B
HAP3
NF-YB
HGNC (Hugo) NFYB
HGNC Alias symbCBF-A
HAP3
NF-YB
HGNC Previous namenuclear transcription factor Y, beta
LocusID (NCBI) 4801
Atlas_Id 41533
Location 12q23.3  [Link to chromosome band 12q23]
Location_base_pair Starts at 104117086 and ends at 104138210 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
BRCA1 (17q21.31) / NFYB (12q23.3)NFYB (12q23.3) / DNAH1 (3p21.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

Nomenclature
HGNC (Hugo)NFYB   7805
Cards
Entrez_Gene (NCBI)NFYB  4801  nuclear transcription factor Y subunit beta
AliasesCBF-A; CBF-B; HAP3; NF-YB
GeneCards (Weizmann)NFYB
Ensembl hg19 (Hinxton)ENSG00000120837 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000120837 [Gene_View]  ENSG00000120837 [Sequence]  chr12:104117086-104138210 [Contig_View]  NFYB [Vega]
ICGC DataPortalENSG00000120837
TCGA cBioPortalNFYB
AceView (NCBI)NFYB
Genatlas (Paris)NFYB
WikiGenes4801
SOURCE (Princeton)NFYB
Genetics Home Reference (NIH)NFYB
Genomic and cartography
GoldenPath hg38 (UCSC)NFYB  -     chr12:104117086-104138210 -  12q23.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)NFYB  -     12q23.3   [Description]    (hg19-Feb_2009)
GoldenPathNFYB - 12q23.3 [CytoView hg19]  NFYB - 12q23.3 [CytoView hg38]
ImmunoBaseENSG00000120837
genome Data Viewer NCBINFYB [Mapview hg19]  
OMIM189904   
Gene and transcription
Genbank (Entrez)AA479300 AK291934 AK311706 AL042186 AU151875
RefSeq transcript (Entrez)NM_006166
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)NFYB
Alternative Splicing GalleryENSG00000120837
Gene ExpressionNFYB [ NCBI-GEO ]   NFYB [ EBI - ARRAY_EXPRESS ]   NFYB [ SEEK ]   NFYB [ MEM ]
Gene Expression Viewer (FireBrowse)NFYB [ Firebrowse - Broad ]
GenevisibleExpression of NFYB in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)4801
GTEX Portal (Tissue expression)NFYB
Human Protein AtlasENSG00000120837-NFYB [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP25208   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP25208  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP25208
Splice isoforms : SwissVarP25208
PhosPhoSitePlusP25208
Domaine pattern : Prosite (Expaxy)NFYB_HAP3 (PS00685)   
Domains : Interpro (EBI)CBFA_NFYB_domain    Histone-fold    Transcrpt_fac_NFYB/HAP3_CS   
Domain families : Pfam (Sanger)CBFD_NFYB_HMF (PF00808)   
Domain families : Pfam (NCBI)pfam00808   
Conserved Domain (NCBI)NFYB
DMDM Disease mutations4801
Blocks (Seattle)NFYB
PDB (RSDB)1N1J    4AWL    4CSR    6QMP    6QMQ    6QMS   
PDB Europe1N1J    4AWL    4CSR    6QMP    6QMQ    6QMS   
PDB (PDBSum)1N1J    4AWL    4CSR    6QMP    6QMQ    6QMS   
PDB (IMB)1N1J    4AWL    4CSR    6QMP    6QMQ    6QMS   
Structural Biology KnowledgeBase1N1J    4AWL    4CSR    6QMP    6QMQ    6QMS   
SCOP (Structural Classification of Proteins)1N1J    4AWL    4CSR    6QMP    6QMQ    6QMS   
CATH (Classification of proteins structures)1N1J    4AWL    4CSR    6QMP    6QMQ    6QMS   
SuperfamilyP25208
Human Protein Atlas [tissue]ENSG00000120837-NFYB [tissue]
Peptide AtlasP25208
HPRD01794
IPIIPI00013217   IPI01021893   
Protein Interaction databases
DIP (DOE-UCLA)P25208
IntAct (EBI)P25208
FunCoupENSG00000120837
BioGRIDNFYB
STRING (EMBL)NFYB
ZODIACNFYB
Ontologies - Pathways
QuickGOP25208
Ontology : AmiGOnuclear chromatin  transcription regulatory region sequence-specific DNA binding  RNA polymerase II proximal promoter sequence-specific DNA binding  RNA polymerase II proximal promoter sequence-specific DNA binding  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA binding  DNA-binding transcription factor activity  protein binding  nucleus  nucleoplasm  regulation of transcription, DNA-templated  regulation of transcription by RNA polymerase II  CCAAT-binding factor complex  CCAAT-binding factor complex  protein-DNA complex  protein-containing complex binding  regulation of cholesterol biosynthetic process  positive regulation of transcription, DNA-templated  protein heterodimerization activity  repressing transcription factor binding  RNA polymerase II transcription factor complex  cellular response to leukemia inhibitory factor  
Ontology : EGO-EBInuclear chromatin  transcription regulatory region sequence-specific DNA binding  RNA polymerase II proximal promoter sequence-specific DNA binding  RNA polymerase II proximal promoter sequence-specific DNA binding  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA binding  DNA-binding transcription factor activity  protein binding  nucleus  nucleoplasm  regulation of transcription, DNA-templated  regulation of transcription by RNA polymerase II  CCAAT-binding factor complex  CCAAT-binding factor complex  protein-DNA complex  protein-containing complex binding  regulation of cholesterol biosynthetic process  positive regulation of transcription, DNA-templated  protein heterodimerization activity  repressing transcription factor binding  RNA polymerase II transcription factor complex  cellular response to leukemia inhibitory factor  
Pathways : KEGGAntigen processing and presentation    Tuberculosis    HTLV-I infection   
NDEx NetworkNFYB
Atlas of Cancer Signalling NetworkNFYB
Wikipedia pathwaysNFYB
Orthology - Evolution
OrthoDB4801
GeneTree (enSembl)ENSG00000120837
Phylogenetic Trees/Animal Genes : TreeFamNFYB
HOGENOMP25208
Homologs : HomoloGeneNFYB
Homology/Alignments : Family Browser (UCSC)NFYB
Gene fusions - Rearrangements
Fusion : QuiverNFYB
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerNFYB [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)NFYB
dbVarNFYB
ClinVarNFYB
MonarchNFYB
1000_GenomesNFYB 
Exome Variant ServerNFYB
GNOMAD BrowserENSG00000120837
Varsome BrowserNFYB
Genetic variants : HAPMAP4801
Genomic Variants (DGV)NFYB [DGVbeta]
DECIPHERNFYB [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisNFYB 
Mutations
ICGC Data PortalNFYB 
TCGA Data PortalNFYB 
Broad Tumor PortalNFYB
OASIS PortalNFYB [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICNFYB  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DNFYB
Mutations and Diseases : HGMDNFYB
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch NFYB
DgiDB (Drug Gene Interaction Database)NFYB
DoCM (Curated mutations)NFYB (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)NFYB (select a term)
intoGenNFYB
Cancer3DNFYB(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM189904   
Orphanet
DisGeNETNFYB
MedgenNFYB
Genetic Testing Registry NFYB
NextProtP25208 [Medical]
TSGene4801
GENETestsNFYB
Target ValidationNFYB
Huge Navigator NFYB [HugePedia]
snp3D : Map Gene to Disease4801
BioCentury BCIQNFYB
ClinGenNFYB
Clinical trials, drugs, therapy
Protein Interactions : CTD4801
Pharm GKB GenePA31610
Clinical trialNFYB
Miscellaneous
canSAR (ICR)NFYB (select the gene name)
HarmonizomeNFYB
DataMed IndexNFYB
Probes
Litterature
PubMed74 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineNFYB
EVEXNFYB
GoPubMedNFYB
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 14 14:24:13 CEST 2020

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