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NFYB (nuclear transcription factor Y subunit beta)

Identity

Alias_namesnuclear transcription factor Y
Alias_symbol (synonym)CBF-A
HAP3
NF-YB
Other aliasCBF-B
HGNC (Hugo) NFYB
LocusID (NCBI) 4801
Atlas_Id 41533
Location 12q23.3  [Link to chromosome band 12q23]
Location_base_pair Starts at 104510858 and ends at 104532040 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
BRCA1 (17q21.31) / NFYB (12q23.3)NFYB (12q23.3) / DNAH1 (3p21.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)NFYB   7805
Cards
Entrez_Gene (NCBI)NFYB  4801  nuclear transcription factor Y subunit beta
AliasesCBF-A; CBF-B; HAP3; NF-YB
GeneCards (Weizmann)NFYB
Ensembl hg19 (Hinxton)ENSG00000120837 [Gene_View]  chr12:104510858-104532040 [Contig_View]  NFYB [Vega]
Ensembl hg38 (Hinxton)ENSG00000120837 [Gene_View]  chr12:104510858-104532040 [Contig_View]  NFYB [Vega]
ICGC DataPortalENSG00000120837
TCGA cBioPortalNFYB
AceView (NCBI)NFYB
Genatlas (Paris)NFYB
WikiGenes4801
SOURCE (Princeton)NFYB
Genetics Home Reference (NIH)NFYB
Genomic and cartography
GoldenPath hg19 (UCSC)NFYB  -     chr12:104510858-104532040 -  12q23.3   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)NFYB  -     12q23.3   [Description]    (hg38-Dec_2013)
EnsemblNFYB - 12q23.3 [CytoView hg19]  NFYB - 12q23.3 [CytoView hg38]
Mapping of homologs : NCBINFYB [Mapview hg19]  NFYB [Mapview hg38]
OMIM189904   
Gene and transcription
Genbank (Entrez)AA479300 AK291934 AK311706 AL042186 AU151875
RefSeq transcript (Entrez)NM_006166
RefSeq genomic (Entrez)NC_000012 NC_018923 NT_029419 NW_004929384
Consensus coding sequences : CCDS (NCBI)NFYB
Cluster EST : UnigeneHs.84928 [ NCBI ]
CGAP (NCI)Hs.84928
Alternative Splicing GalleryENSG00000120837
Gene ExpressionNFYB [ NCBI-GEO ]   NFYB [ EBI - ARRAY_EXPRESS ]   NFYB [ SEEK ]   NFYB [ MEM ]
Gene Expression Viewer (FireBrowse)NFYB [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)4801
GTEX Portal (Tissue expression)NFYB
Protein : pattern, domain, 3D structure
UniProt/SwissProtP25208   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP25208  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP25208
Splice isoforms : SwissVarP25208
PhosPhoSitePlusP25208
Domaine pattern : Prosite (Expaxy)NFYB_HAP3 (PS00685)   
Domains : Interpro (EBI)CBFA_NFYB_domain    Histone-fold    Transcrpt_fac_NFYB/HAP3_CS   
Domain families : Pfam (Sanger)CBFD_NFYB_HMF (PF00808)   
Domain families : Pfam (NCBI)pfam00808   
Conserved Domain (NCBI)NFYB
DMDM Disease mutations4801
Blocks (Seattle)NFYB
PDB (SRS)1N1J    4AWL    4CSR   
PDB (PDBSum)1N1J    4AWL    4CSR   
PDB (IMB)1N1J    4AWL    4CSR   
PDB (RSDB)1N1J    4AWL    4CSR   
Structural Biology KnowledgeBase1N1J    4AWL    4CSR   
SCOP (Structural Classification of Proteins)1N1J    4AWL    4CSR   
CATH (Classification of proteins structures)1N1J    4AWL    4CSR   
SuperfamilyP25208
Human Protein AtlasENSG00000120837
Peptide AtlasP25208
HPRD01794
IPIIPI00013217   IPI01021893   
Protein Interaction databases
DIP (DOE-UCLA)P25208
IntAct (EBI)P25208
FunCoupENSG00000120837
BioGRIDNFYB
STRING (EMBL)NFYB
ZODIACNFYB
Ontologies - Pathways
QuickGOP25208
Ontology : AmiGODNA binding  transcription factor activity, sequence-specific DNA binding  protein binding  nucleus  nucleoplasm  transcription, DNA-templated  regulation of transcription, DNA-templated  CCAAT-binding factor complex  protein complex binding  protein-DNA complex  sequence-specific DNA binding  transcription regulatory region DNA binding  positive regulation of transcription, DNA-templated  protein heterodimerization activity  repressing transcription factor binding  
Ontology : EGO-EBIDNA binding  transcription factor activity, sequence-specific DNA binding  protein binding  nucleus  nucleoplasm  transcription, DNA-templated  regulation of transcription, DNA-templated  CCAAT-binding factor complex  protein complex binding  protein-DNA complex  sequence-specific DNA binding  transcription regulatory region DNA binding  positive regulation of transcription, DNA-templated  protein heterodimerization activity  repressing transcription factor binding  
Pathways : BIOCARTAOverview of telomerase RNA component gene hTerc Transcriptional Regulation [Genes]   
Pathways : KEGGAntigen processing and presentation    Tuberculosis    HTLV-I infection   
NDEx NetworkNFYB
Atlas of Cancer Signalling NetworkNFYB
Wikipedia pathwaysNFYB
Orthology - Evolution
OrthoDB4801
GeneTree (enSembl)ENSG00000120837
Phylogenetic Trees/Animal Genes : TreeFamNFYB
HOVERGENP25208
HOGENOMP25208
Homologs : HomoloGeneNFYB
Homology/Alignments : Family Browser (UCSC)NFYB
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerNFYB [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)NFYB
dbVarNFYB
ClinVarNFYB
1000_GenomesNFYB 
Exome Variant ServerNFYB
ExAC (Exome Aggregation Consortium)NFYB (select the gene name)
Genetic variants : HAPMAP4801
Genomic Variants (DGV)NFYB [DGVbeta]
DECIPHER (Syndromes)12:104510858-104532040  ENSG00000120837
CONAN: Copy Number AnalysisNFYB 
Mutations
ICGC Data PortalNFYB 
TCGA Data PortalNFYB 
Broad Tumor PortalNFYB
OASIS PortalNFYB [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICNFYB  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDNFYB
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch NFYB
DgiDB (Drug Gene Interaction Database)NFYB
DoCM (Curated mutations)NFYB (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)NFYB (select a term)
intoGenNFYB
Cancer3DNFYB(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM189904   
Orphanet
MedgenNFYB
Genetic Testing Registry NFYB
NextProtP25208 [Medical]
TSGene4801
GENETestsNFYB
Huge Navigator NFYB [HugePedia]
snp3D : Map Gene to Disease4801
BioCentury BCIQNFYB
ClinGenNFYB
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD4801
Chemical/Pharm GKB GenePA31610
Clinical trialNFYB
Miscellaneous
canSAR (ICR)NFYB (select the gene name)
Probes
Litterature
PubMed62 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineNFYB
EVEXNFYB
GoPubMedNFYB
iHOPNFYB
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Mar 30 15:12:13 CEST 2017

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