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NID1 (nidogen 1)

Identity

Alias (NCBI)NID
HGNC (Hugo) NID1
HGNC Alias symbentactin
HGNC Previous nameNID
HGNC Previous namenidogen (enactin)
LocusID (NCBI) 4811
Atlas_Id 47530
Location 1q42.3  [Link to chromosome band 1q42]
Location_base_pair Starts at 235975832 and ends at 236065090 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ETV6 (12p13.2) / NID1 (1q42.3)LYST (1q42.3) / NID1 (1q42.3)NID1 (1q42.3) / FAM92A1 (8q22.1)
NID1 (1q42.3) / HADHA (2p23.3)NID1 (1q42.3) / NID1 (1q42.3)NID1 (1q42.3) / SQRDL (15q21.1)
SQRDL (15q21.1) / NID1 (1q42.3)LYST 1q42.3 / NID1 1q42.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



Other Leukemias implicated (Data extracted from papers in the Atlas) [ 1 ]
  t(1;12)(q42;p13) ETV6/NID1


External links

 

Nomenclature
HGNC (Hugo)NID1   7821
Cards
Entrez_Gene (NCBI)NID1    nidogen 1
AliasesNID
GeneCards (Weizmann)NID1
Ensembl hg19 (Hinxton)ENSG00000116962 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000116962 [Gene_View]  ENSG00000116962 [Sequence]  chr1:235975832-236065090 [Contig_View]  NID1 [Vega]
ICGC DataPortalENSG00000116962
TCGA cBioPortalNID1
AceView (NCBI)NID1
Genatlas (Paris)NID1
SOURCE (Princeton)NID1
Genetics Home Reference (NIH)NID1
Genomic and cartography
GoldenPath hg38 (UCSC)NID1  -     chr1:235975832-236065090 -  1q42.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)NID1  -     1q42.3   [Description]    (hg19-Feb_2009)
GoldenPathNID1 - 1q42.3 [CytoView hg19]  NID1 - 1q42.3 [CytoView hg38]
ImmunoBaseENSG00000116962
Genome Data Viewer NCBINID1 [Mapview hg19]  
OMIM131390   
Gene and transcription
Genbank (Entrez)AB209448 AK297234 BC012501 BC045606 BQ549657
RefSeq transcript (Entrez)NM_002508
Consensus coding sequences : CCDS (NCBI)NID1
Gene ExpressionNID1 [ NCBI-GEO ]   NID1 [ EBI - ARRAY_EXPRESS ]   NID1 [ SEEK ]   NID1 [ MEM ]
Gene Expression Viewer (FireBrowse)NID1 [ Firebrowse - Broad ]
GenevisibleExpression of NID1 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)4811
GTEX Portal (Tissue expression)NID1
Human Protein AtlasENSG00000116962-NID1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP14543   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP14543  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP14543
PhosPhoSitePlusP14543
Domaine pattern : Prosite (Expaxy)ASX_HYDROXYL (PS00010)    EGF_1 (PS00022)    EGF_2 (PS01186)    EGF_3 (PS50026)    EGF_CA (PS01187)    LDLRB (PS51120)    NIDO (PS51220)    NIDOGEN_G2 (PS50993)    THYROGLOBULIN_1_1 (PS00484)    THYROGLOBULIN_1_2 (PS51162)   
Domains : Interpro (EBI)6-blade_b-propeller_TolB-like    cEGF    EGF-like_Ca-bd_dom    EGF-like_dom    EGF-type_Asp/Asn_hydroxyl_site    EGF_Ca-bd_CS    EGF_dom    G2_nidogen/fibulin_G2F    GFP    Growth_fac_rcpt_cys_sf    LDLR_classB_rpt    NIDO_dom    Thyroglobulin_1    Thyroglobulin_1_sf   
Domain families : Pfam (Sanger)cEGF (PF12662)    EGF_3 (PF12947)    EGF_CA (PF07645)    G2F (PF07474)    Ldl_recept_b (PF00058)    NIDO (PF06119)    Thyroglobulin_1 (PF00086)   
Domain families : Pfam (NCBI)pfam12662    pfam12947    pfam07645    pfam07474    pfam00058    pfam06119    pfam00086   
Domain families : Smart (EMBL)EGF (SM00181)  EGF_CA (SM00179)  G2F (SM00682)  LY (SM00135)  NIDO (SM00539)  TY (SM00211)  
Conserved Domain (NCBI)NID1
PDB (RSDB)1NDX   
PDB Europe1NDX   
PDB (PDBSum)1NDX   
PDB (IMB)1NDX   
Structural Biology KnowledgeBase1NDX   
SCOP (Structural Classification of Proteins)1NDX   
CATH (Classification of proteins structures)1NDX   
SuperfamilyP14543
AlphaFold pdb e-kbP14543   
Human Protein Atlas [tissue]ENSG00000116962-NID1 [tissue]
HPRD00574
Protein Interaction databases
DIP (DOE-UCLA)P14543
IntAct (EBI)P14543
BioGRIDNID1
STRING (EMBL)NID1
ZODIACNID1
Ontologies - Pathways
QuickGOP14543
Ontology : AmiGOextracellular matrix structural constituent  extracellular matrix structural constituent  calcium ion binding  collagen binding  extracellular region  basement membrane  plasma membrane  cell-matrix adhesion  positive regulation of cell-substrate adhesion  extracellular matrix organization  glomerular basement membrane development  laminin binding  laminin-1 binding  proteoglycan binding  collagen-containing extracellular matrix  collagen-containing extracellular matrix  collagen-containing extracellular matrix  extracellular exosome  basement membrane organization  
Ontology : EGO-EBIextracellular matrix structural constituent  extracellular matrix structural constituent  calcium ion binding  collagen binding  extracellular region  basement membrane  plasma membrane  cell-matrix adhesion  positive regulation of cell-substrate adhesion  extracellular matrix organization  glomerular basement membrane development  laminin binding  laminin-1 binding  proteoglycan binding  collagen-containing extracellular matrix  collagen-containing extracellular matrix  collagen-containing extracellular matrix  extracellular exosome  basement membrane organization  
NDEx NetworkNID1
Atlas of Cancer Signalling NetworkNID1
Wikipedia pathwaysNID1
Orthology - Evolution
OrthoDB4811
GeneTree (enSembl)ENSG00000116962
Phylogenetic Trees/Animal Genes : TreeFamNID1
Homologs : HomoloGeneNID1
Homology/Alignments : Family Browser (UCSC)NID1
Gene fusions - Rearrangements
Fusion : MitelmanLYST/NID1 [1q42.3/1q42.3]  
Fusion : QuiverNID1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerNID1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)NID1
dbVarNID1
ClinVarNID1
MonarchNID1
1000_GenomesNID1 
Exome Variant ServerNID1
GNOMAD BrowserENSG00000116962
Varsome BrowserNID1
ACMGNID1 variants
VarityP14543
Genomic Variants (DGV)NID1 [DGVbeta]
DECIPHERNID1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisNID1 
Mutations
ICGC Data PortalNID1 
TCGA Data PortalNID1 
Broad Tumor PortalNID1
OASIS PortalNID1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICNID1  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DNID1
Mutations and Diseases : HGMDNID1
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaNID1
DgiDB (Drug Gene Interaction Database)NID1
DoCM (Curated mutations)NID1
CIViC (Clinical Interpretations of Variants in Cancer)NID1
Cancer3DNID1
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM131390   
Orphanet
DisGeNETNID1
MedgenNID1
Genetic Testing Registry NID1
NextProtP14543 [Medical]
GENETestsNID1
Target ValidationNID1
Huge Navigator NID1 [HugePedia]
ClinGenNID1
Clinical trials, drugs, therapy
MyCancerGenomeNID1
Protein Interactions : CTDNID1
Pharm GKB GenePA31625
PharosP14543
Clinical trialNID1
Miscellaneous
canSAR (ICR)NID1
HarmonizomeNID1
DataMed IndexNID1
Probes
Litterature
PubMed73 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXNID1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Oct 4 15:22:45 CEST 2021

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