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NID2 (nidogen 2)

Identity

Other aliasNID-2
HGNC (Hugo) NID2
LocusID (NCBI) 22795
Atlas_Id 47531
Location 14q22.1  [Link to chromosome band 14q22]
Location_base_pair Starts at 52004802 and ends at 52069228 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)		BANP (16q24.2) / NID2 (14q22.1)NID2 (14q22.1) / RAB7A (3q21.3)NID2 (14q22.1) / ZFP91 (11q12.1)
PIAS4 (19p13.3) / NID2 (14q22.1)TRDMT1 (10p13) / NID2 (14q22.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

Other Leukemias implicated (Data extracted from papers in the Atlas) [ 1 ]
  t(11;14)(p15;q22) AP2A2/NID2

External links

Nomenclature
HGNC (Hugo)NID2   13389
Cards
Entrez_Gene (NCBI)NID2  22795  nidogen 2
AliasesNID-2
GeneCards (Weizmann)NID2
Ensembl hg19 (Hinxton)ENSG00000087303 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000087303 [Gene_View]  chr14:52004802-52069228 [Contig_View]  NID2 [Vega]
ICGC DataPortalENSG00000087303
TCGA cBioPortalNID2
AceView (NCBI)NID2
Genatlas (Paris)NID2
WikiGenes22795
SOURCE (Princeton)NID2
Genetics Home Reference (NIH)NID2
Genomic and cartography
GoldenPath hg38 (UCSC)NID2  -     chr14:52004802-52069228 -  14q22.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)NID2  -     14q22.1   [Description]    (hg19-Feb_2009)
EnsemblNID2 - 14q22.1 [CytoView hg19]  NID2 - 14q22.1 [CytoView hg38]
Mapping of homologs : NCBINID2 [Mapview hg19]  NID2 [Mapview hg38]
OMIM605399   
Gene and transcription
Genbank (Entrez)AJ223500 AK291652 AK298542 AK300462 AL701794
RefSeq transcript (Entrez)NM_007361
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)NID2
Cluster EST : UnigeneHs.369840 [ NCBI ]
CGAP (NCI)Hs.369840
Alternative Splicing GalleryENSG00000087303
Gene ExpressionNID2 [ NCBI-GEO ]   NID2 [ EBI - ARRAY_EXPRESS ]   NID2 [ SEEK ]   NID2 [ MEM ]
Gene Expression Viewer (FireBrowse)NID2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)22795
GTEX Portal (Tissue expression)NID2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ14112   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ14112  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ14112
Splice isoforms : SwissVarQ14112
PhosPhoSitePlusQ14112
Domaine pattern : Prosite (Expaxy)ASX_HYDROXYL (PS00010)    EGF_2 (PS01186)    EGF_3 (PS50026)    EGF_CA (PS01187)    LDLRB (PS51120)    NIDO (PS51220)    NIDOGEN_G2 (PS50993)    THYROGLOBULIN_1_1 (PS00484)    THYROGLOBULIN_1_2 (PS51162)   
Domains : Interpro (EBI)6-blade_b-propeller_TolB-like    cEGF    EGF-like_Ca-bd_dom    EGF-like_CS    EGF-like_dom    EGF-type_Asp/Asn_hydroxyl_site    EGF_Ca-bd_CS    EGF_dom    G2_nidogen/fibulin_G2F    GFP    GFP-like    Growth_fac_rcpt_    LDLR_classB_rpt    NIDO_dom    Thyroglobulin_1   
Domain families : Pfam (Sanger)cEGF (PF12662)    EGF_3 (PF12947)    EGF_CA (PF07645)    G2F (PF07474)    Ldl_recept_b (PF00058)    NIDO (PF06119)    Thyroglobulin_1 (PF00086)   
Domain families : Pfam (NCBI)pfam12662    pfam12947    pfam07645    pfam07474    pfam00058    pfam06119    pfam00086   
Domain families : Smart (EMBL)EGF (SM00181)  EGF_CA (SM00179)  G2F (SM00682)  LY (SM00135)  NIDO (SM00539)  TY (SM00211)  
Conserved Domain (NCBI)NID2
DMDM Disease mutations22795
Blocks (Seattle)NID2
SuperfamilyQ14112
Human Protein AtlasENSG00000087303
Peptide AtlasQ14112
HPRD05654
IPIIPI00028908   IPI00955436   IPI01024785   IPI00293033   IPI00745450   
Protein Interaction databases
DIP (DOE-UCLA)Q14112
IntAct (EBI)Q14112
FunCoupENSG00000087303
BioGRIDNID2
STRING (EMBL)NID2
ZODIACNID2
Ontologies - Pathways
QuickGOQ14112
Ontology : AmiGOcalcium ion binding  protein binding  collagen binding  extracellular region  basement membrane  extracellular space  plasma membrane  cell adhesion  cell-matrix adhesion  extracellular matrix organization  extracellular matrix  extracellular matrix  extracellular matrix  extracellular exosome  basement membrane organization  
Ontology : EGO-EBIcalcium ion binding  protein binding  collagen binding  extracellular region  basement membrane  extracellular space  plasma membrane  cell adhesion  cell-matrix adhesion  extracellular matrix organization  extracellular matrix  extracellular matrix  extracellular matrix  extracellular exosome  basement membrane organization  
NDEx NetworkNID2
Atlas of Cancer Signalling NetworkNID2
Wikipedia pathwaysNID2
Orthology - Evolution
OrthoDB22795
GeneTree (enSembl)ENSG00000087303
Phylogenetic Trees/Animal Genes : TreeFamNID2
HOVERGENQ14112
HOGENOMQ14112
Homologs : HomoloGeneNID2
Homology/Alignments : Family Browser (UCSC)NID2
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerNID2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)NID2
dbVarNID2
ClinVarNID2
1000_GenomesNID2 
Exome Variant ServerNID2
ExAC (Exome Aggregation Consortium)NID2 (select the gene name)
Genetic variants : HAPMAP22795
Genomic Variants (DGV)NID2 [DGVbeta]
DECIPHERNID2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisNID2 
Mutations
ICGC Data PortalNID2 
TCGA Data PortalNID2 
Broad Tumor PortalNID2
OASIS PortalNID2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICNID2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDNID2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch NID2
DgiDB (Drug Gene Interaction Database)NID2
DoCM (Curated mutations)NID2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)NID2 (select a term)
intoGenNID2
Cancer3DNID2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM605399   
Orphanet
MedgenNID2
Genetic Testing Registry NID2
NextProtQ14112 [Medical]
TSGene22795
GENETestsNID2
Target ValidationNID2
Huge Navigator NID2 [HugePedia]
snp3D : Map Gene to Disease22795
BioCentury BCIQNID2
ClinGenNID2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD22795
Chemical/Pharm GKB GenePA31626
Clinical trialNID2
Miscellaneous
canSAR (ICR)NID2 (select the gene name)
Probes
Litterature
PubMed31 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineNID2
EVEXNID2
GoPubMedNID2
iHOPNID2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Jun 7 12:46:51 CEST 2017
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