NINJ2 (ninjurin 2)

2014-11-01  

Identity

HGNC
NINJ2
LOCATION
12p13.33
LOCUSID
4815
ALIAS
-
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 4815
MIM: 607297
HGNC: 7825
Ensembl: ENSG00000171840

Variants:

dbSNP: 4815
ClinVar: 4815
TCGA: ENSG00000171840
COSMIC: NINJ2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000171840ENST00000305108Q9NZG7
ENSG00000171840ENST00000397265F8WBZ3
ENSG00000171840ENST00000433832B4DNS9
ENSG00000171840ENST00000542920F5H3L1
ENSG00000171840ENST00000662884A0A590UJR9

Expression (GTEx)

0
5
10
15
20
25
30
35
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

References

Pubmed IDYearTitleCitations
193696582009Genomewide association studies of stroke.180
204105252010Failure to validate association between 12p13 variants and ischemic stroke.30
213763212011No evidence for association of 12p13 SNPs rs11833579 and rs12425791 within NINJ2 gene with ischemic stroke in Chinese Han population.10
216740032011Genetic polymorphisms of a novel vascular susceptibility gene, Ninjurin2 (NINJ2), are associated with a decreased risk of Alzheimer's disease.8
217229212011NINJ2 polymorphism is associated with ischemic stroke in Chinese Han population.5
222973882012Association between 12p13 SNPs rs11833579/rs12425791 near NINJ2 gene and ischemic stroke in East Asian population: evidence from a meta-analysis.4
284319862017NINJ2- A novel regulator of endothelial inflammation and activation.4
303181192018Targeting ninjurin 2 by miR-764 regulates hydrogen peroxide (H<sub>2</sub>O<sub>2</sub>)-induced neuronal cell death.4
224297332012NINJ2 SNP may affect the onset age of first-ever ischemic stroke without increasing silent cerebrovascular lesions.2
249598322014Associations of NINJ2 sequence variants with incident ischemic stroke in the Cohorts for Heart and Aging in Genomic Epidemiology (CHARGE) consortium.2

Citation

Dessen P

NINJ2 (ninjurin 2)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/70835/ninj2