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NIT1 (nitrilase 1)

Identity

Other alias-
HGNC (Hugo) NIT1
LocusID (NCBI) 4817
Atlas_Id 46248
Location 1q23.3  [Link to chromosome band 1q23]
Location_base_pair Starts at 161118072 and ends at 161125445 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
SCN2A (2q24.3) / NIT1 (1q23.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)NIT1   7828
Cards
Entrez_Gene (NCBI)NIT1  4817  nitrilase 1
Aliases
GeneCards (Weizmann)NIT1
Ensembl hg19 (Hinxton)ENSG00000158793 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000158793 [Gene_View]  chr1:161118072-161125445 [Contig_View]  NIT1 [Vega]
ICGC DataPortalENSG00000158793
TCGA cBioPortalNIT1
AceView (NCBI)NIT1
Genatlas (Paris)NIT1
WikiGenes4817
SOURCE (Princeton)NIT1
Genetics Home Reference (NIH)NIT1
Genomic and cartography
GoldenPath hg38 (UCSC)NIT1  -     chr1:161118072-161125445 +  1q23.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)NIT1  -     1q23.3   [Description]    (hg19-Feb_2009)
EnsemblNIT1 - 1q23.3 [CytoView hg19]  NIT1 - 1q23.3 [CytoView hg38]
Mapping of homologs : NCBINIT1 [Mapview hg19]  NIT1 [Mapview hg38]
OMIM604618   
Gene and transcription
Genbank (Entrez)AF069987 AI277603 AK296606 AK313323 AY893504
RefSeq transcript (Entrez)NM_001185092 NM_001185093 NM_001185094 NM_005600
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)NIT1
Cluster EST : UnigeneHs.146406 [ NCBI ]
CGAP (NCI)Hs.146406
Alternative Splicing GalleryENSG00000158793
Gene ExpressionNIT1 [ NCBI-GEO ]   NIT1 [ EBI - ARRAY_EXPRESS ]   NIT1 [ SEEK ]   NIT1 [ MEM ]
Gene Expression Viewer (FireBrowse)NIT1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)4817
GTEX Portal (Tissue expression)NIT1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ86X76   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ86X76  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ86X76
Splice isoforms : SwissVarQ86X76
PhosPhoSitePlusQ86X76
Domaine pattern : Prosite (Expaxy)CN_HYDROLASE (PS50263)    UPF0012 (PS01227)   
Domains : Interpro (EBI)C-N_Hydrolase    UPF0012_CS   
Domain families : Pfam (Sanger)CN_hydrolase (PF00795)   
Domain families : Pfam (NCBI)pfam00795   
Conserved Domain (NCBI)NIT1
DMDM Disease mutations4817
Blocks (Seattle)NIT1
SuperfamilyQ86X76
Human Protein AtlasENSG00000158793
Peptide AtlasQ86X76
HPRD07056
IPIIPI00023779   IPI00456663   IPI00456664   IPI00456665   IPI00903236   
Protein Interaction databases
DIP (DOE-UCLA)Q86X76
IntAct (EBI)Q86X76
FunCoupENSG00000158793
BioGRIDNIT1
STRING (EMBL)NIT1
ZODIACNIT1
Ontologies - Pathways
QuickGOQ86X76
Ontology : AmiGOnitrilase activity  nucleus  mitochondrion  nitrogen compound metabolic process  biological_process  extracellular exosome  
Ontology : EGO-EBInitrilase activity  nucleus  mitochondrion  nitrogen compound metabolic process  biological_process  extracellular exosome  
NDEx NetworkNIT1
Atlas of Cancer Signalling NetworkNIT1
Wikipedia pathwaysNIT1
Orthology - Evolution
OrthoDB4817
GeneTree (enSembl)ENSG00000158793
Phylogenetic Trees/Animal Genes : TreeFamNIT1
HOVERGENQ86X76
HOGENOMQ86X76
Homologs : HomoloGeneNIT1
Homology/Alignments : Family Browser (UCSC)NIT1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerNIT1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)NIT1
dbVarNIT1
ClinVarNIT1
1000_GenomesNIT1 
Exome Variant ServerNIT1
ExAC (Exome Aggregation Consortium)NIT1 (select the gene name)
Genetic variants : HAPMAP4817
Genomic Variants (DGV)NIT1 [DGVbeta]
DECIPHERNIT1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisNIT1 
Mutations
ICGC Data PortalNIT1 
TCGA Data PortalNIT1 
Broad Tumor PortalNIT1
OASIS PortalNIT1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICNIT1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDNIT1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch NIT1
DgiDB (Drug Gene Interaction Database)NIT1
DoCM (Curated mutations)NIT1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)NIT1 (select a term)
intoGenNIT1
Cancer3DNIT1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM604618   
Orphanet
MedgenNIT1
Genetic Testing Registry NIT1
NextProtQ86X76 [Medical]
TSGene4817
GENETestsNIT1
Target ValidationNIT1
Huge Navigator NIT1 [HugePedia]
snp3D : Map Gene to Disease4817
BioCentury BCIQNIT1
ClinGenNIT1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD4817
Chemical/Pharm GKB GenePA31636
Clinical trialNIT1
Miscellaneous
canSAR (ICR)NIT1 (select the gene name)
Probes
Litterature
PubMed18 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineNIT1
EVEXNIT1
GoPubMedNIT1
iHOPNIT1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Aug 1 17:09:07 CEST 2017

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