Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 /Indexbychrom/idxa_3.html">3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

NKD1 (naked cuticle homolog 1)

Identity

Alias_namesnaked cuticle homolog 1 (Drosophila)
Other aliasNaked1
HGNC (Hugo) NKD1
LocusID (NCBI) 85407
Atlas_Id 51466
Location 16q12.1  [Link to chromosome band 16q12]
Location_base_pair Starts at 50548330 and ends at 50640860 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
KMT2A (11q23.3) / NKD1 (16q12.1)NKD1 (16q12.1) / ADCY7 (16q12.1)NKD1 (16q12.1) / LOC440354 ()

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)NKD1   17045
Cards
Entrez_Gene (NCBI)NKD1  85407  naked cuticle homolog 1
AliasesNaked1
GeneCards (Weizmann)NKD1
Ensembl hg19 (Hinxton)ENSG00000140807 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000140807 [Gene_View]  chr16:50548330-50640860 [Contig_View]  NKD1 [Vega]
ICGC DataPortalENSG00000140807
TCGA cBioPortalNKD1
AceView (NCBI)NKD1
Genatlas (Paris)NKD1
WikiGenes85407
SOURCE (Princeton)NKD1
Genetics Home Reference (NIH)NKD1
Genomic and cartography
GoldenPath hg38 (UCSC)NKD1  -     chr16:50548330-50640860 +  16q12.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)NKD1  -     16q12.1   [Description]    (hg19-Feb_2009)
EnsemblNKD1 - 16q12.1 [CytoView hg19]  NKD1 - 16q12.1 [CytoView hg38]
Mapping of homologs : NCBINKD1 [Mapview hg19]  NKD1 [Mapview hg38]
OMIM607851   
Gene and transcription
Genbank (Entrez)AB062886 AF289584 AF358135 AK000276 AK021701
RefSeq transcript (Entrez)NM_033119
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)NKD1
Cluster EST : UnigeneHs.187578 [ NCBI ]
CGAP (NCI)Hs.187578
Alternative Splicing GalleryENSG00000140807
Gene ExpressionNKD1 [ NCBI-GEO ]   NKD1 [ EBI - ARRAY_EXPRESS ]   NKD1 [ SEEK ]   NKD1 [ MEM ]
Gene Expression Viewer (FireBrowse)NKD1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)85407
GTEX Portal (Tissue expression)NKD1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ969G9   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ969G9  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ969G9
Splice isoforms : SwissVarQ969G9
PhosPhoSitePlusQ969G9
Domaine pattern : Prosite (Expaxy)EF_HAND_1 (PS00018)    EF_HAND_2 (PS50222)   
Domains : Interpro (EBI)EF-hand-dom_pair    EF_Hand_1_Ca_BS    EF_hand_dom   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Conserved Domain (NCBI)NKD1
DMDM Disease mutations85407
Blocks (Seattle)NKD1
SuperfamilyQ969G9
Human Protein AtlasENSG00000140807
Peptide AtlasQ969G9
HPRD08482
IPIIPI00056339   
Protein Interaction databases
DIP (DOE-UCLA)Q969G9
IntAct (EBI)Q969G9
FunCoupENSG00000140807
BioGRIDNKD1
STRING (EMBL)NKD1
ZODIACNKD1
Ontologies - Pathways
QuickGOQ969G9
Ontology : AmiGOprotein phosphatase type 2A complex  eye photoreceptor cell differentiation  calcium ion binding  protein binding  cytoplasm  plasma membrane  somatic muscle development  Wnt signaling pathway  PDZ domain binding  positive regulation of protein catabolic process  negative regulation of canonical Wnt signaling pathway  negative regulation of canonical Wnt signaling pathway  regulation of cell motility involved in somitogenic axis elongation  positive regulation of non-canonical Wnt signaling pathway via JNK cascade  negative regulation of convergent extension involved in axis elongation  positive regulation of Wnt signaling pathway, planar cell polarity pathway  
Ontology : EGO-EBIprotein phosphatase type 2A complex  eye photoreceptor cell differentiation  calcium ion binding  protein binding  cytoplasm  plasma membrane  somatic muscle development  Wnt signaling pathway  PDZ domain binding  positive regulation of protein catabolic process  negative regulation of canonical Wnt signaling pathway  negative regulation of canonical Wnt signaling pathway  regulation of cell motility involved in somitogenic axis elongation  positive regulation of non-canonical Wnt signaling pathway via JNK cascade  negative regulation of convergent extension involved in axis elongation  positive regulation of Wnt signaling pathway, planar cell polarity pathway  
Pathways : KEGGWnt signaling pathway    Hippo signaling pathway   
NDEx NetworkNKD1
Atlas of Cancer Signalling NetworkNKD1
Wikipedia pathwaysNKD1
Orthology - Evolution
OrthoDB85407
GeneTree (enSembl)ENSG00000140807
Phylogenetic Trees/Animal Genes : TreeFamNKD1
HOVERGENQ969G9
HOGENOMQ969G9
Homologs : HomoloGeneNKD1
Homology/Alignments : Family Browser (UCSC)NKD1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerNKD1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)NKD1
dbVarNKD1
ClinVarNKD1
1000_GenomesNKD1 
Exome Variant ServerNKD1
ExAC (Exome Aggregation Consortium)NKD1 (select the gene name)
Genetic variants : HAPMAP85407
Genomic Variants (DGV)NKD1 [DGVbeta]
DECIPHERNKD1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisNKD1 
Mutations
ICGC Data PortalNKD1 
TCGA Data PortalNKD1 
Broad Tumor PortalNKD1
OASIS PortalNKD1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICNKD1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDNKD1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch NKD1
DgiDB (Drug Gene Interaction Database)NKD1
DoCM (Curated mutations)NKD1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)NKD1 (select a term)
intoGenNKD1
Cancer3DNKD1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM607851   
Orphanet
MedgenNKD1
Genetic Testing Registry NKD1
NextProtQ969G9 [Medical]
TSGene85407
GENETestsNKD1
Target ValidationNKD1
Huge Navigator NKD1 [HugePedia]
snp3D : Map Gene to Disease85407
BioCentury BCIQNKD1
ClinGenNKD1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD85407
Chemical/Pharm GKB GenePA31637
Clinical trialNKD1
Miscellaneous
canSAR (ICR)NKD1 (select the gene name)
Probes
Litterature
PubMed14 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineNKD1
EVEXNKD1
GoPubMedNKD1
iHOPNKD1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Sep 25 19:22:12 CEST 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.