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NKIRAS1 (NFKB inhibitor interacting Ras like 1)

Identity

Alias_namesNFKB inhibitor interacting Ras-like protein 1
Alias_symbol (synonym)KBRAS1
kappaB-Ras1
Other alias
HGNC (Hugo) NKIRAS1
LocusID (NCBI) 28512
Atlas_Id 51791
Location 3p24.2  [Link to chromosome band 3p24]
Location_base_pair Starts at 23892081 and ends at 23917046 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
APBB2 (4p14) / NKIRAS1 (3p24.2)DKC1 (Xq28) / NKIRAS1 (3p24.2)HLA-DPA1 (6p21.32) / NKIRAS1 (3p24.2)
NKIRAS1 (3p24.2) / CXCL8 (4q13.3)NKIRAS1 (3p24.2) / MRPL9 (1q21.3)NKIRAS1 (3p24.2) / NHSL1 (6q23.3)
NKIRAS1 (3p24.2) / NKIRAS1 (3p24.2)NKIRAS1 (3p24.2) / TGOLN2 (2p11.2)TMEM263 (12q23.3) / NKIRAS1 (3p24.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)NKIRAS1   17899
Cards
Entrez_Gene (NCBI)NKIRAS1  28512  NFKB inhibitor interacting Ras like 1
AliasesKBRAS1; kappaB-Ras1
GeneCards (Weizmann)NKIRAS1
Ensembl hg19 (Hinxton)ENSG00000197885 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000197885 [Gene_View]  ENSG00000197885 [Sequence]  chr3:23892081-23917046 [Contig_View]  NKIRAS1 [Vega]
ICGC DataPortalENSG00000197885
TCGA cBioPortalNKIRAS1
AceView (NCBI)NKIRAS1
Genatlas (Paris)NKIRAS1
WikiGenes28512
SOURCE (Princeton)NKIRAS1
Genetics Home Reference (NIH)NKIRAS1
Genomic and cartography
GoldenPath hg38 (UCSC)NKIRAS1  -     chr3:23892081-23917046 -  3p24.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)NKIRAS1  -     3p24.2   [Description]    (hg19-Feb_2009)
EnsemblNKIRAS1 - 3p24.2 [CytoView hg19]  NKIRAS1 - 3p24.2 [CytoView hg38]
Mapping of homologs : NCBINKIRAS1 [Mapview hg19]  NKIRAS1 [Mapview hg38]
OMIM604496   
Gene and transcription
Genbank (Entrez)AF229839 AK027749 BC012145 BC066940 BG713995
RefSeq transcript (Entrez)NM_020345
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)NKIRAS1
Cluster EST : UnigeneHs.173202 [ NCBI ]
CGAP (NCI)Hs.173202
Alternative Splicing GalleryENSG00000197885
Gene ExpressionNKIRAS1 [ NCBI-GEO ]   NKIRAS1 [ EBI - ARRAY_EXPRESS ]   NKIRAS1 [ SEEK ]   NKIRAS1 [ MEM ]
Gene Expression Viewer (FireBrowse)NKIRAS1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)28512
GTEX Portal (Tissue expression)NKIRAS1
Human Protein AtlasENSG00000197885-NKIRAS1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NYS0   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9NYS0  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9NYS0
Splice isoforms : SwissVarQ9NYS0
PhosPhoSitePlusQ9NYS0
Domaine pattern : Prosite (Expaxy)RAB (PS51419)   
Domains : Interpro (EBI)P-loop_NTPase    Small_GTP-bd_dom    Small_GTPase    Small_GTPase_Ras   
Domain families : Pfam (Sanger)Ras (PF00071)   
Domain families : Pfam (NCBI)pfam00071   
Conserved Domain (NCBI)NKIRAS1
DMDM Disease mutations28512
Blocks (Seattle)NKIRAS1
SuperfamilyQ9NYS0
Human Protein Atlas [tissue]ENSG00000197885-NKIRAS1 [tissue]
Peptide AtlasQ9NYS0
HPRD06841
IPIIPI00410705   IPI01014656   
Protein Interaction databases
DIP (DOE-UCLA)Q9NYS0
IntAct (EBI)Q9NYS0
FunCoupENSG00000197885
BioGRIDNKIRAS1
STRING (EMBL)NKIRAS1
ZODIACNKIRAS1
Ontologies - Pathways
QuickGOQ9NYS0
Ontology : AmiGOGTPase activity  GTP binding  cellular_component  cytoplasm  I-kappaB kinase/NF-kappaB signaling  membrane  
Ontology : EGO-EBIGTPase activity  GTP binding  cellular_component  cytoplasm  I-kappaB kinase/NF-kappaB signaling  membrane  
NDEx NetworkNKIRAS1
Atlas of Cancer Signalling NetworkNKIRAS1
Wikipedia pathwaysNKIRAS1
Orthology - Evolution
OrthoDB28512
GeneTree (enSembl)ENSG00000197885
Phylogenetic Trees/Animal Genes : TreeFamNKIRAS1
HOVERGENQ9NYS0
HOGENOMQ9NYS0
Homologs : HomoloGeneNKIRAS1
Homology/Alignments : Family Browser (UCSC)NKIRAS1
Gene fusions - Rearrangements
Fusion : QuiverNKIRAS1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerNKIRAS1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)NKIRAS1
dbVarNKIRAS1
ClinVarNKIRAS1
1000_GenomesNKIRAS1 
Exome Variant ServerNKIRAS1
ExAC (Exome Aggregation Consortium)ENSG00000197885
GNOMAD BrowserENSG00000197885
Varsome BrowserNKIRAS1
Genetic variants : HAPMAP28512
Genomic Variants (DGV)NKIRAS1 [DGVbeta]
DECIPHERNKIRAS1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisNKIRAS1 
Mutations
ICGC Data PortalNKIRAS1 
TCGA Data PortalNKIRAS1 
Broad Tumor PortalNKIRAS1
OASIS PortalNKIRAS1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICNKIRAS1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDNKIRAS1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch NKIRAS1
DgiDB (Drug Gene Interaction Database)NKIRAS1
DoCM (Curated mutations)NKIRAS1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)NKIRAS1 (select a term)
intoGenNKIRAS1
Cancer3DNKIRAS1(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM604496   
Orphanet
DisGeNETNKIRAS1
MedgenNKIRAS1
Genetic Testing Registry NKIRAS1
NextProtQ9NYS0 [Medical]
TSGene28512
GENETestsNKIRAS1
Target ValidationNKIRAS1
Huge Navigator NKIRAS1 [HugePedia]
snp3D : Map Gene to Disease28512
BioCentury BCIQNKIRAS1
ClinGenNKIRAS1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD28512
Chemical/Pharm GKB GenePA134958823
Clinical trialNKIRAS1
Miscellaneous
canSAR (ICR)NKIRAS1 (select the gene name)
Probes
Litterature
PubMed16 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineNKIRAS1
EVEXNKIRAS1
GoPubMedNKIRAS1
iHOPNKIRAS1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Nov 6 11:26:17 CET 2018
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