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NKIRAS2 (NFKB inhibitor interacting Ras like 2)

Identity

Alias_namesNFKB inhibitor interacting Ras-like protein 2
NFKB inhibitor interacting Ras-like 2
Alias_symbol (synonym)KBRAS2
DKFZP434N1526
kappaB-Ras2
Other alias
HGNC (Hugo) NKIRAS2
LocusID (NCBI) 28511
Atlas_Id 70852
Location 17q21.2  [Link to chromosome band 17q21]
Location_base_pair Starts at 42017576 and ends at 42025638 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
MECP2 (Xq28) / NKIRAS2 (17q21.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)NKIRAS2   17898
Cards
Entrez_Gene (NCBI)NKIRAS2  28511  NFKB inhibitor interacting Ras like 2
AliasesKBRAS2; kappaB-Ras2
GeneCards (Weizmann)NKIRAS2
Ensembl hg19 (Hinxton)ENSG00000168256 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000168256 [Gene_View]  chr17:42017576-42025638 [Contig_View]  NKIRAS2 [Vega]
ICGC DataPortalENSG00000168256
TCGA cBioPortalNKIRAS2
AceView (NCBI)NKIRAS2
Genatlas (Paris)NKIRAS2
WikiGenes28511
SOURCE (Princeton)NKIRAS2
Genetics Home Reference (NIH)NKIRAS2
Genomic and cartography
GoldenPath hg38 (UCSC)NKIRAS2  -     chr17:42017576-42025638 +  17q21.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)NKIRAS2  -     17q21.2   [Description]    (hg19-Feb_2009)
EnsemblNKIRAS2 - 17q21.2 [CytoView hg19]  NKIRAS2 - 17q21.2 [CytoView hg38]
Mapping of homologs : NCBINKIRAS2 [Mapview hg19]  NKIRAS2 [Mapview hg38]
OMIM604497   
Gene and transcription
Genbank (Entrez)AF229840 AK027265 AK054571 AK297975 AL137682
RefSeq transcript (Entrez)NM_001001349 NM_001144927 NM_001144928 NM_001144929 NM_017595
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)NKIRAS2
Cluster EST : UnigeneHs.632252 [ NCBI ]
CGAP (NCI)Hs.632252
Alternative Splicing GalleryENSG00000168256
Gene ExpressionNKIRAS2 [ NCBI-GEO ]   NKIRAS2 [ EBI - ARRAY_EXPRESS ]   NKIRAS2 [ SEEK ]   NKIRAS2 [ MEM ]
Gene Expression Viewer (FireBrowse)NKIRAS2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)28511
GTEX Portal (Tissue expression)NKIRAS2
Human Protein AtlasENSG00000168256-NKIRAS2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NYR9   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9NYR9  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9NYR9
Splice isoforms : SwissVarQ9NYR9
PhosPhoSitePlusQ9NYR9
Domaine pattern : Prosite (Expaxy)RAB (PS51419)   
Domains : Interpro (EBI)P-loop_NTPase    Small_GTP-bd_dom    Small_GTPase    Small_GTPase_Ras   
Domain families : Pfam (Sanger)Ras (PF00071)   
Domain families : Pfam (NCBI)pfam00071   
Conserved Domain (NCBI)NKIRAS2
DMDM Disease mutations28511
Blocks (Seattle)NKIRAS2
SuperfamilyQ9NYR9
Human Protein Atlas [tissue]ENSG00000168256-NKIRAS2 [tissue]
Peptide AtlasQ9NYR9
HPRD07261
IPIIPI00021124   IPI00738016   IPI01018231   IPI00921434   IPI00789320   IPI00791151   
Protein Interaction databases
DIP (DOE-UCLA)Q9NYR9
IntAct (EBI)Q9NYR9
FunCoupENSG00000168256
BioGRIDNKIRAS2
STRING (EMBL)NKIRAS2
ZODIACNKIRAS2
Ontologies - Pathways
QuickGOQ9NYR9
Ontology : AmiGOGTPase activity  GTP binding  cellular_component  cytoplasm  I-kappaB kinase/NF-kappaB signaling  membrane  
Ontology : EGO-EBIGTPase activity  GTP binding  cellular_component  cytoplasm  I-kappaB kinase/NF-kappaB signaling  membrane  
NDEx NetworkNKIRAS2
Atlas of Cancer Signalling NetworkNKIRAS2
Wikipedia pathwaysNKIRAS2
Orthology - Evolution
OrthoDB28511
GeneTree (enSembl)ENSG00000168256
Phylogenetic Trees/Animal Genes : TreeFamNKIRAS2
HOVERGENQ9NYR9
HOGENOMQ9NYR9
Homologs : HomoloGeneNKIRAS2
Homology/Alignments : Family Browser (UCSC)NKIRAS2
Gene fusions - Rearrangements
Fusion: Tumor Portal NKIRAS2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerNKIRAS2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)NKIRAS2
dbVarNKIRAS2
ClinVarNKIRAS2
1000_GenomesNKIRAS2 
Exome Variant ServerNKIRAS2
ExAC (Exome Aggregation Consortium)ENSG00000168256
GNOMAD BrowserENSG00000168256
Genetic variants : HAPMAP28511
Genomic Variants (DGV)NKIRAS2 [DGVbeta]
DECIPHERNKIRAS2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisNKIRAS2 
Mutations
ICGC Data PortalNKIRAS2 
TCGA Data PortalNKIRAS2 
Broad Tumor PortalNKIRAS2
OASIS PortalNKIRAS2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICNKIRAS2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDNKIRAS2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch NKIRAS2
DgiDB (Drug Gene Interaction Database)NKIRAS2
DoCM (Curated mutations)NKIRAS2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)NKIRAS2 (select a term)
intoGenNKIRAS2
Cancer3DNKIRAS2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM604497   
Orphanet
MedgenNKIRAS2
Genetic Testing Registry NKIRAS2
NextProtQ9NYR9 [Medical]
TSGene28511
GENETestsNKIRAS2
Target ValidationNKIRAS2
Huge Navigator NKIRAS2 [HugePedia]
snp3D : Map Gene to Disease28511
BioCentury BCIQNKIRAS2
ClinGenNKIRAS2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD28511
Chemical/Pharm GKB GenePA134968907
Clinical trialNKIRAS2
Miscellaneous
canSAR (ICR)NKIRAS2 (select the gene name)
Probes
Litterature
PubMed11 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineNKIRAS2
EVEXNKIRAS2
GoPubMedNKIRAS2
iHOPNKIRAS2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Nov 9 12:19:02 CET 2017

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