Atlas of Genetics and Cytogenetics in Oncology and Haematology


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NKX1-1 (NK1 homeobox 1)

Identity

Alias_namesNK1 transcription factor related, locus 1 (Drosophila)
Alias_symbol (synonym)HSPX153
SAX2
Other aliasNKX-1.1
HGNC (Hugo) NKX1-1
LocusID (NCBI) 54729
Atlas_Id 70854
Location 4p16.3  [Link to chromosome band 4p16]
Location_base_pair Starts at 1402932 and ends at 1406442 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)NKX1-1   24975
Cards
Entrez_Gene (NCBI)NKX1-1  54729  NK1 homeobox 1
AliasesHSPX153; NKX-1.1; SAX2
GeneCards (Weizmann)NKX1-1
Ensembl hg19 (Hinxton)ENSG00000235608 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000235608 [Gene_View]  chr4:1402932-1406442 [Contig_View]  NKX1-1 [Vega]
ICGC DataPortalENSG00000235608
TCGA cBioPortalNKX1-1
AceView (NCBI)NKX1-1
Genatlas (Paris)NKX1-1
WikiGenes54729
SOURCE (Princeton)NKX1-1
Genetics Home Reference (NIH)NKX1-1
Genomic and cartography
GoldenPath hg38 (UCSC)NKX1-1  -     chr4:1402932-1406442 -  4p16.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)NKX1-1  -     4p16.3   [Description]    (hg19-Feb_2009)
EnsemblNKX1-1 - 4p16.3 [CytoView hg19]  NKX1-1 - 4p16.3 [CytoView hg38]
Mapping of homologs : NCBINKX1-1 [Mapview hg19]  NKX1-1 [Mapview hg38]
Gene and transcription
Genbank (Entrez)X76978
RefSeq transcript (Entrez)NM_001290079
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)NKX1-1
Cluster EST : UnigeneHs.526396 [ NCBI ]
CGAP (NCI)Hs.526396
Alternative Splicing GalleryENSG00000235608
Gene ExpressionNKX1-1 [ NCBI-GEO ]   NKX1-1 [ EBI - ARRAY_EXPRESS ]   NKX1-1 [ SEEK ]   NKX1-1 [ MEM ]
Gene Expression Viewer (FireBrowse)NKX1-1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)54729
GTEX Portal (Tissue expression)NKX1-1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ15270   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ15270  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ15270
Splice isoforms : SwissVarQ15270
PhosPhoSitePlusQ15270
Domaine pattern : Prosite (Expaxy)HOMEOBOX_1 (PS00027)    HOMEOBOX_2 (PS50071)   
Domains : Interpro (EBI)Homeobox-like    Homeobox_CS    Homeobox_dom    Homeobox_metazoa   
Domain families : Pfam (Sanger)Homeobox (PF00046)   
Domain families : Pfam (NCBI)pfam00046   
Domain families : Smart (EMBL)HOX (SM00389)  
Conserved Domain (NCBI)NKX1-1
DMDM Disease mutations54729
Blocks (Seattle)NKX1-1
SuperfamilyQ15270
Human Protein AtlasENSG00000235608
Peptide AtlasQ15270
IPIIPI00015783   
Protein Interaction databases
DIP (DOE-UCLA)Q15270
IntAct (EBI)Q15270
FunCoupENSG00000235608
BioGRIDNKX1-1
STRING (EMBL)NKX1-1
ZODIACNKX1-1
Ontologies - Pathways
QuickGOQ15270
Ontology : AmiGOnucleus  regulation of transcription, DNA-templated  lipid metabolic process  biological_process  regulation of glucose metabolic process  regulation of generation of precursor metabolites and energy  sequence-specific DNA binding  neurological system process  
Ontology : EGO-EBInucleus  regulation of transcription, DNA-templated  lipid metabolic process  biological_process  regulation of glucose metabolic process  regulation of generation of precursor metabolites and energy  sequence-specific DNA binding  neurological system process  
NDEx NetworkNKX1-1
Atlas of Cancer Signalling NetworkNKX1-1
Wikipedia pathwaysNKX1-1
Orthology - Evolution
OrthoDB54729
GeneTree (enSembl)ENSG00000235608
Phylogenetic Trees/Animal Genes : TreeFamNKX1-1
HOVERGENQ15270
HOGENOMQ15270
Homologs : HomoloGeneNKX1-1
Homology/Alignments : Family Browser (UCSC)NKX1-1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerNKX1-1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)NKX1-1
dbVarNKX1-1
ClinVarNKX1-1
1000_GenomesNKX1-1 
Exome Variant ServerNKX1-1
ExAC (Exome Aggregation Consortium)NKX1-1 (select the gene name)
Genetic variants : HAPMAP54729
Genomic Variants (DGV)NKX1-1 [DGVbeta]
DECIPHERNKX1-1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisNKX1-1 
Mutations
ICGC Data PortalNKX1-1 
TCGA Data PortalNKX1-1 
Broad Tumor PortalNKX1-1
OASIS PortalNKX1-1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICNKX1-1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDNKX1-1
BioMutasearch NKX1-1
DgiDB (Drug Gene Interaction Database)NKX1-1
DoCM (Curated mutations)NKX1-1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)NKX1-1 (select a term)
intoGenNKX1-1
Cancer3DNKX1-1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenNKX1-1
Genetic Testing Registry NKX1-1
NextProtQ15270 [Medical]
TSGene54729
GENETestsNKX1-1
Target ValidationNKX1-1
Huge Navigator NKX1-1 [HugePedia]
snp3D : Map Gene to Disease54729
BioCentury BCIQNKX1-1
ClinGenNKX1-1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD54729
Chemical/Pharm GKB GenePA145148380
Clinical trialNKX1-1
Miscellaneous
canSAR (ICR)NKX1-1 (select the gene name)
Probes
Litterature
PubMed2 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineNKX1-1
EVEXNKX1-1
GoPubMedNKX1-1
iHOPNKX1-1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed May 31 15:32:43 CEST 2017

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