Atlas of Genetics and Cytogenetics in Oncology and Haematology


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NKX1-2 (NK1 homeobox 2)

Identity

Alias_namesC10orf121
chromosome 10 open reading frame 121
NK1 transcription factor related, locus 2 (Drosophila)
Alias_symbol (synonym)bB238F13.2
Other aliasNKX-1.1
HGNC (Hugo) NKX1-2
LocusID (NCBI) 390010
Atlas_Id 70855
Location 10q26.13  [Link to chromosome band 10q26]
Location_base_pair Starts at 124447429 and ends at 124449981 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)NKX1-2   31652
Cards
Entrez_Gene (NCBI)NKX1-2  390010  NK1 homeobox 2
AliasesC10orf121; NKX-1.1; bB238F13.2
GeneCards (Weizmann)NKX1-2
Ensembl hg19 (Hinxton) [Gene_View]
Ensembl hg38 (Hinxton) [Gene_View]  chr10:124447429-124449981 [Contig_View]  NKX1-2 [Vega]
TCGA cBioPortalNKX1-2
AceView (NCBI)NKX1-2
Genatlas (Paris)NKX1-2
WikiGenes390010
SOURCE (Princeton)NKX1-2
Genetics Home Reference (NIH)NKX1-2
Genomic and cartography
GoldenPath hg38 (UCSC)NKX1-2  -     chr10:124447429-124449981 -  10q26.13   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)NKX1-2  -     10q26.13   [Description]    (hg19-Feb_2009)
EnsemblNKX1-2 - 10q26.13 [CytoView hg19]  NKX1-2 - 10q26.13 [CytoView hg38]
Mapping of homologs : NCBINKX1-2 [Mapview hg19]  NKX1-2 [Mapview hg38]
Gene and transcription
Genbank (Entrez)-
RefSeq transcript (Entrez)NM_001146340
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)NKX1-2
Cluster EST : UnigeneHs.712041 [ NCBI ]
CGAP (NCI)Hs.712041
Gene ExpressionNKX1-2 [ NCBI-GEO ]   NKX1-2 [ EBI - ARRAY_EXPRESS ]   NKX1-2 [ SEEK ]   NKX1-2 [ MEM ]
Gene Expression Viewer (FireBrowse)NKX1-2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)390010
GTEX Portal (Tissue expression)NKX1-2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9UD57   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9UD57  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9UD57
Splice isoforms : SwissVarQ9UD57
PhosPhoSitePlusQ9UD57
Domaine pattern : Prosite (Expaxy)HOMEOBOX_1 (PS00027)    HOMEOBOX_2 (PS50071)   
Domains : Interpro (EBI)Homeobox-like    Homeobox_CS    Homeobox_dom    Homeobox_metazoa   
Domain families : Pfam (Sanger)Homeobox (PF00046)   
Domain families : Pfam (NCBI)pfam00046   
Domain families : Smart (EMBL)HOX (SM00389)  
Conserved Domain (NCBI)NKX1-2
DMDM Disease mutations390010
Blocks (Seattle)NKX1-2
SuperfamilyQ9UD57
Peptide AtlasQ9UD57
IPIIPI00374738   IPI01025971   
Protein Interaction databases
DIP (DOE-UCLA)Q9UD57
IntAct (EBI)Q9UD57
BioGRIDNKX1-2
STRING (EMBL)NKX1-2
ZODIACNKX1-2
Ontologies - Pathways
QuickGOQ9UD57
Ontology : AmiGOnucleus  regulation of transcription, DNA-templated  multicellular organism development  sequence-specific DNA binding  
Ontology : EGO-EBInucleus  regulation of transcription, DNA-templated  multicellular organism development  sequence-specific DNA binding  
NDEx NetworkNKX1-2
Atlas of Cancer Signalling NetworkNKX1-2
Wikipedia pathwaysNKX1-2
Orthology - Evolution
OrthoDB390010
Phylogenetic Trees/Animal Genes : TreeFamNKX1-2
HOVERGENQ9UD57
HOGENOMQ9UD57
Homologs : HomoloGeneNKX1-2
Homology/Alignments : Family Browser (UCSC)NKX1-2
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerNKX1-2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)NKX1-2
dbVarNKX1-2
ClinVarNKX1-2
1000_GenomesNKX1-2 
Exome Variant ServerNKX1-2
ExAC (Exome Aggregation Consortium)NKX1-2 (select the gene name)
Genetic variants : HAPMAP390010
Genomic Variants (DGV)NKX1-2 [DGVbeta]
DECIPHERNKX1-2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisNKX1-2 
Mutations
ICGC Data PortalNKX1-2 
TCGA Data PortalNKX1-2 
Broad Tumor PortalNKX1-2
OASIS PortalNKX1-2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICNKX1-2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDNKX1-2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch NKX1-2
DgiDB (Drug Gene Interaction Database)NKX1-2
DoCM (Curated mutations)NKX1-2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)NKX1-2 (select a term)
intoGenNKX1-2
Cancer3DNKX1-2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenNKX1-2
Genetic Testing Registry NKX1-2
NextProtQ9UD57 [Medical]
TSGene390010
GENETestsNKX1-2
Target ValidationNKX1-2
Huge Navigator NKX1-2 [HugePedia]
snp3D : Map Gene to Disease390010
BioCentury BCIQNKX1-2
ClinGenNKX1-2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD390010
Chemical/Pharm GKB GenePA134977174
Clinical trialNKX1-2
Miscellaneous
canSAR (ICR)NKX1-2 (select the gene name)
Probes
Litterature
PubMed3 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineNKX1-2
EVEXNKX1-2
GoPubMedNKX1-2
iHOPNKX1-2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed May 31 15:32:43 CEST 2017

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