Atlas of Genetics and Cytogenetics in Oncology and Haematology


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NKX2-4 (NK2 homeobox 4)

Identity

Alias_namesNKX2D
NK-2 (Drosophila) homolog D
NK2 transcription factor related, locus 4 (Drosophila)
Alias_symbol (synonym)NKX2.4
Other alias
HGNC (Hugo) NKX2-4
LocusID (NCBI) 644524
Atlas_Id 70857
Location 20p11.22  [Link to chromosome band 20p11]
Location_base_pair Starts at 21395367 and ends at 21397409 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)NKX2-4   7837
Cards
Entrez_Gene (NCBI)NKX2-4  644524  NK2 homeobox 4
AliasesNKX2.4; NKX2D
GeneCards (Weizmann)NKX2-4
Ensembl hg19 (Hinxton) [Gene_View]
Ensembl hg38 (Hinxton) [Gene_View]  chr20:21395367-21397409 [Contig_View]  NKX2-4 [Vega]
TCGA cBioPortalNKX2-4
AceView (NCBI)NKX2-4
Genatlas (Paris)NKX2-4
WikiGenes644524
SOURCE (Princeton)NKX2-4
Genetics Home Reference (NIH)NKX2-4
Genomic and cartography
GoldenPath hg38 (UCSC)NKX2-4  -     chr20:21395367-21397409 -  20p11.22   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)NKX2-4  -     20p11.22   [Description]    (hg19-Feb_2009)
EnsemblNKX2-4 - 20p11.22 [CytoView hg19]  NKX2-4 - 20p11.22 [CytoView hg38]
Mapping of homologs : NCBINKX2-4 [Mapview hg19]  NKX2-4 [Mapview hg38]
OMIM607808   
Gene and transcription
Genbank (Entrez)-
RefSeq transcript (Entrez)NM_033176
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)NKX2-4
Cluster EST : UnigeneHs.456662 [ NCBI ]
CGAP (NCI)Hs.456662
Gene ExpressionNKX2-4 [ NCBI-GEO ]   NKX2-4 [ EBI - ARRAY_EXPRESS ]   NKX2-4 [ SEEK ]   NKX2-4 [ MEM ]
Gene Expression Viewer (FireBrowse)NKX2-4 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)644524
GTEX Portal (Tissue expression)NKX2-4
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9H2Z4   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9H2Z4  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9H2Z4
Splice isoforms : SwissVarQ9H2Z4
PhosPhoSitePlusQ9H2Z4
Domaine pattern : Prosite (Expaxy)HOMEOBOX_1 (PS00027)    HOMEOBOX_2 (PS50071)   
Domains : Interpro (EBI)Homeobox-like    Homeobox_CS    Homeobox_dom    Homeobox_metazoa   
Domain families : Pfam (Sanger)Homeobox (PF00046)   
Domain families : Pfam (NCBI)pfam00046   
Domain families : Smart (EMBL)HOX (SM00389)  
Conserved Domain (NCBI)NKX2-4
DMDM Disease mutations644524
Blocks (Seattle)NKX2-4
SuperfamilyQ9H2Z4
Peptide AtlasQ9H2Z4
IPIIPI00830084   
Protein Interaction databases
DIP (DOE-UCLA)Q9H2Z4
IntAct (EBI)Q9H2Z4
BioGRIDNKX2-4
STRING (EMBL)NKX2-4
ZODIACNKX2-4
Ontologies - Pathways
QuickGOQ9H2Z4
Ontology : AmiGOmolecular_function  cellular_component  nucleus  regulation of transcription, DNA-templated  multicellular organism development  biological_process  sequence-specific DNA binding  
Ontology : EGO-EBImolecular_function  cellular_component  nucleus  regulation of transcription, DNA-templated  multicellular organism development  biological_process  sequence-specific DNA binding  
NDEx NetworkNKX2-4
Atlas of Cancer Signalling NetworkNKX2-4
Wikipedia pathwaysNKX2-4
Orthology - Evolution
OrthoDB644524
Phylogenetic Trees/Animal Genes : TreeFamNKX2-4
HOVERGENQ9H2Z4
HOGENOMQ9H2Z4
Homologs : HomoloGeneNKX2-4
Homology/Alignments : Family Browser (UCSC)NKX2-4
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerNKX2-4 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)NKX2-4
dbVarNKX2-4
ClinVarNKX2-4
1000_GenomesNKX2-4 
Exome Variant ServerNKX2-4
ExAC (Exome Aggregation Consortium)NKX2-4 (select the gene name)
Genetic variants : HAPMAP644524
Genomic Variants (DGV)NKX2-4 [DGVbeta]
DECIPHERNKX2-4 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisNKX2-4 
Mutations
ICGC Data PortalNKX2-4 
TCGA Data PortalNKX2-4 
Broad Tumor PortalNKX2-4
OASIS PortalNKX2-4 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICNKX2-4  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDNKX2-4
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch NKX2-4
DgiDB (Drug Gene Interaction Database)NKX2-4
DoCM (Curated mutations)NKX2-4 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)NKX2-4 (select a term)
intoGenNKX2-4
Cancer3DNKX2-4(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM607808   
Orphanet
MedgenNKX2-4
Genetic Testing Registry NKX2-4
NextProtQ9H2Z4 [Medical]
TSGene644524
GENETestsNKX2-4
Target ValidationNKX2-4
Huge Navigator NKX2-4 [HugePedia]
snp3D : Map Gene to Disease644524
BioCentury BCIQNKX2-4
ClinGenNKX2-4
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD644524
Chemical/Pharm GKB GenePA31644
Clinical trialNKX2-4
Miscellaneous
canSAR (ICR)NKX2-4 (select the gene name)
Probes
Litterature
PubMed4 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineNKX2-4
EVEXNKX2-4
GoPubMedNKX2-4
iHOPNKX2-4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 18 13:32:05 CEST 2017

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