| Nomenclature |
HGNC (Hugo) | NKX2-8 16364 |
| Cards |
Entrez_Gene (NCBI) | NKX2-8 NK2 homeobox 8 |
Aliases | NKX2.8; NKX2H; Nkx2-9 |
GeneCards (Weizmann) | NKX2-8 |
Ensembl hg19 (Hinxton) | ENSG00000136327 [Gene_View] |
Ensembl hg38 (Hinxton) | ENSG00000136327 [Gene_View]  ENSG00000136327 [Sequence] chr14:36580004-36582614 [Contig_View] NKX2-8 [Vega] |
ICGC DataPortal | ENSG00000136327 |
TCGA cBioPortal | NKX2-8 |
AceView (NCBI) | NKX2-8 |
Genatlas (Paris) | NKX2-8 |
SOURCE (Princeton) | NKX2-8 |
Genetics Home Reference (NIH) | NKX2-8 |
| Genomic and cartography |
GoldenPath hg38 (UCSC) | NKX2-8 - chr14:36580004-36582614 - 14q13.3 [Description] (hg38-Dec_2013) |
GoldenPath hg19 (UCSC) | NKX2-8 - 14q13.3 [Description] (hg19-Feb_2009) |
GoldenPath | NKX2-8 - 14q13.3 [CytoView hg19] NKX2-8 - 14q13.3 [CytoView hg38] |
ImmunoBase | ENSG00000136327 |
genome Data Viewer NCBI | NKX2-8 [Mapview hg19] |
OMIM | 603245 |
| Gene and transcription |
Genbank (Entrez) | AF000295 AK313537 BC041090 DA438523 |
RefSeq transcript (Entrez) | NM_014360 |
RefSeq genomic (Entrez) | |
Consensus coding sequences : CCDS (NCBI) | NKX2-8 |
Alternative Splicing Gallery | ENSG00000136327 |
Gene Expression | NKX2-8 [ NCBI-GEO ] NKX2-8 [ EBI - ARRAY_EXPRESS ]
NKX2-8 [ SEEK ] NKX2-8 [ MEM ] |
Gene Expression Viewer (FireBrowse) | NKX2-8 [ Firebrowse - Broad ] |
Genevisible | Expression of NKX2-8 in : [tissues]  [cell-lines]  [cancer]  [perturbations]   |
BioGPS (Tissue expression) | 26257 |
GTEX Portal (Tissue expression) | NKX2-8 |
Human Protein Atlas | ENSG00000136327-NKX2-8 [pathology] [cell] [tissue] |
| Protein : pattern, domain, 3D structure |
UniProt/SwissProt | O15522 [function] [subcellular_location] [family_and_domains] [pathology_and_biotech] [ptm_processing] [expression] [interaction] |
NextProt | O15522 [Sequence] [Exons] [Medical] [Publications] |
With graphics : InterPro | O15522 |
Splice isoforms : SwissVar | O15522 |
PhosPhoSitePlus | O15522 |
Domaine pattern : Prosite (Expaxy) | HOMEOBOX_1 (PS00027) HOMEOBOX_2 (PS50071) |
Domains : Interpro (EBI) | Homeobox-like_sf Homeobox_CS Homeobox_dom Homeobox_metazoa |
Domain families : Pfam (Sanger) | Homeodomain (PF00046) |
Domain families : Pfam (NCBI) | pfam00046 |
Domain families : Smart (EMBL) | HOX (SM00389) |
Conserved Domain (NCBI) | NKX2-8 |
Blocks (Seattle) | NKX2-8 |
Superfamily | O15522 |
Human Protein Atlas [tissue] | ENSG00000136327-NKX2-8 [tissue] |
Peptide Atlas | O15522 |
HPRD | 04456 |
IPI | IPI00007308 |
| Protein Interaction databases |
DIP (DOE-UCLA) | O15522 |
IntAct (EBI) | O15522 |
BioGRID | NKX2-8 |
STRING (EMBL) | NKX2-8 |
ZODIAC | NKX2-8 |
| Ontologies - Pathways |
QuickGO | O15522 |
Ontology : AmiGO | nuclear chromatin RNA polymerase II proximal promoter sequence-specific DNA binding RNA polymerase II proximal promoter sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific liver development double-stranded DNA binding DNA-binding transcription factor activity DNA-binding transcription factor activity cellular_component nucleus transcription, DNA-templated transcription by RNA polymerase II axonogenesis cell differentiation lung development sequence-specific DNA binding sequence-specific DNA binding positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II negative regulation of epithelial cell proliferation |
Ontology : EGO-EBI | nuclear chromatin RNA polymerase II proximal promoter sequence-specific DNA binding RNA polymerase II proximal promoter sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific liver development double-stranded DNA binding DNA-binding transcription factor activity DNA-binding transcription factor activity cellular_component nucleus transcription, DNA-templated transcription by RNA polymerase II axonogenesis cell differentiation lung development sequence-specific DNA binding sequence-specific DNA binding positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II negative regulation of epithelial cell proliferation |
NDEx Network | NKX2-8 |
Atlas of Cancer Signalling Network | NKX2-8 |
Wikipedia pathways | NKX2-8 |
| Orthology - Evolution |
OrthoDB | 26257 |
GeneTree (enSembl) | ENSG00000136327 |
Phylogenetic Trees/Animal Genes : TreeFam | NKX2-8 |
HOGENOM | O15522 |
Homologs : HomoloGene | NKX2-8 |
Homology/Alignments : Family Browser (UCSC) | NKX2-8 |
| Gene fusions - Rearrangements |
Fusion : Quiver | NKX2-8 |
| Polymorphisms : SNP and Copy number variants |
NCBI Variation Viewer | NKX2-8 [hg38] |
dbVar | NKX2-8 |
ClinVar | NKX2-8 |
Monarch | NKX2-8 |
1000_Genomes | NKX2-8 |
Exome Variant Server | NKX2-8 |
GNOMAD Browser | ENSG00000136327 |
Varsome Browser | NKX2-8 |
Genomic Variants (DGV) | NKX2-8 [DGVbeta] |
DECIPHER | NKX2-8 [patients] [syndromes] [variants] [genes] |
CONAN: Copy Number Analysis | NKX2-8 |
| Mutations |
ICGC Data Portal | NKX2-8 |
TCGA Data Portal | NKX2-8 |
Broad Tumor Portal | NKX2-8 |
OASIS Portal | NKX2-8 [ Somatic mutations - Copy number] |
Somatic Mutations in Cancer : COSMIC | NKX2-8 [overview] [genome browser] [tissue] [distribution] |
Somatic Mutations in Cancer : COSMIC3D | NKX2-8 |
Mutations and Diseases : HGMD | NKX2-8 |
LOVD (Leiden Open Variation Database) | Whole genome datasets |
LOVD (Leiden Open Variation Database) | LOVD - Leiden Open Variation Database |
LOVD (Leiden Open Variation Database) | LOVD 3.0 shared installation |
BioMuta | search NKX2-8 |
DgiDB (Drug Gene Interaction Database) | NKX2-8 |
DoCM (Curated mutations) | NKX2-8 (select the gene name) |
CIViC (Clinical Interpretations of Variants in Cancer) | NKX2-8 (select a term) |
intoGen | NKX2-8 |
Cancer3D | NKX2-8(select the gene name) |
Impact of mutations | [PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser] |
| Diseases |
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OMIM | 603245 |
Orphanet | |
DisGeNET | NKX2-8 |
Medgen | NKX2-8 |
Genetic Testing Registry | NKX2-8
|
NextProt | O15522 [Medical] |
GENETests | NKX2-8 |
Target Validation | NKX2-8 |
Huge Navigator |
NKX2-8 [HugePedia] |
ClinGen | NKX2-8 |
| Clinical trials, drugs, therapy |
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MyCancerGenome | NKX2-8 |
Protein Interactions : CTD | |
Pharm GKB Gene | PA38402 |
Pharos | O15522 |
Clinical trial | NKX2-8 |
| Miscellaneous |
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canSAR (ICR) | NKX2-8 (select the gene name) |
Harmonizome | NKX2-8 |
DataMed Index | NKX2-8 |
| Probes |
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| Litterature |
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PubMed | 20 Pubmed reference(s) in Entrez |
GeneRIFs | Gene References Into Functions (Entrez) |
EVEX | NKX2-8 |