Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

NKX6-2 (NK6 homeobox 2)

Identity

Alias_namesNK6 transcription factor related, locus 2 (Drosophila)
Alias_symbol (synonym)NKX6B
GTX
NKX6.1
Other aliasNKX6.2
HGNC (Hugo) NKX6-2
LocusID (NCBI) 84504
Atlas_Id 70860
Location 10q26.3  [Link to chromosome band 10q26]
Location_base_pair Starts at 132784816 and ends at 132786033 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)NKX6-2   19321
Cards
Entrez_Gene (NCBI)NKX6-2  84504  NK6 homeobox 2
AliasesGTX; NKX6.2; NKX6B
GeneCards (Weizmann)NKX6-2
Ensembl hg19 (Hinxton) [Gene_View]
Ensembl hg38 (Hinxton) [Gene_View]   [Sequence]  chr10:132784816-132786033 [Contig_View]  NKX6-2 [Vega]
TCGA cBioPortalNKX6-2
AceView (NCBI)NKX6-2
Genatlas (Paris)NKX6-2
WikiGenes84504
SOURCE (Princeton)NKX6-2
Genetics Home Reference (NIH)NKX6-2
Genomic and cartography
GoldenPath hg38 (UCSC)NKX6-2  -     chr10:132784816-132786033 -  10q26.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)NKX6-2  -     10q26.3   [Description]    (hg19-Feb_2009)
EnsemblNKX6-2 - 10q26.3 [CytoView hg19]  NKX6-2 - 10q26.3 [CytoView hg38]
Mapping of homologs : NCBINKX6-2 [Mapview hg19]  NKX6-2 [Mapview hg38]
OMIM605955   
Gene and transcription
Genbank (Entrez)BC101635 BC104823 BF509028
RefSeq transcript (Entrez)NM_177400
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)NKX6-2
Cluster EST : UnigeneHs.134013 [ NCBI ]
CGAP (NCI)Hs.134013
Gene ExpressionNKX6-2 [ NCBI-GEO ]   NKX6-2 [ EBI - ARRAY_EXPRESS ]   NKX6-2 [ SEEK ]   NKX6-2 [ MEM ]
Gene Expression Viewer (FireBrowse)NKX6-2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)84504
GTEX Portal (Tissue expression)NKX6-2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9C056   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9C056  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9C056
Splice isoforms : SwissVarQ9C056
PhosPhoSitePlusQ9C056
Domaine pattern : Prosite (Expaxy)HOMEOBOX_1 (PS00027)    HOMEOBOX_2 (PS50071)   
Domains : Interpro (EBI)Homeobox-like    Homeobox_CS    Homeobox_dom    Homeobox_metazoa    HTH_motif   
Domain families : Pfam (Sanger)Homeobox (PF00046)   
Domain families : Pfam (NCBI)pfam00046   
Domain families : Smart (EMBL)HOX (SM00389)  
Conserved Domain (NCBI)NKX6-2
DMDM Disease mutations84504
Blocks (Seattle)NKX6-2
SuperfamilyQ9C056
Peptide AtlasQ9C056
HPRD09336
IPIIPI00028161   
Protein Interaction databases
DIP (DOE-UCLA)Q9C056
IntAct (EBI)Q9C056
BioGRIDNKX6-2
STRING (EMBL)NKX6-2
ZODIACNKX6-2
Ontologies - Pathways
QuickGOQ9C056
Ontology : AmiGO###############################################################################################################################################################################################################################################################                              
Ontology : EGO-EBI###############################################################################################################################################################################################################################################################                              
NDEx NetworkNKX6-2
Atlas of Cancer Signalling NetworkNKX6-2
Wikipedia pathwaysNKX6-2
Orthology - Evolution
OrthoDB84504
Phylogenetic Trees/Animal Genes : TreeFamNKX6-2
HOVERGENQ9C056
HOGENOMQ9C056
Homologs : HomoloGeneNKX6-2
Homology/Alignments : Family Browser (UCSC)NKX6-2
Gene fusions - Rearrangements
Fusion : QuiverNKX6-2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerNKX6-2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)NKX6-2
dbVarNKX6-2
ClinVarNKX6-2
1000_GenomesNKX6-2 
Exome Variant ServerNKX6-2
Varsome BrowserNKX6-2
Genetic variants : HAPMAP84504
Genomic Variants (DGV)NKX6-2 [DGVbeta]
DECIPHERNKX6-2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisNKX6-2 
Mutations
ICGC Data PortalNKX6-2 
TCGA Data PortalNKX6-2 
Broad Tumor PortalNKX6-2
OASIS PortalNKX6-2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICNKX6-2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDNKX6-2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch NKX6-2
DgiDB (Drug Gene Interaction Database)NKX6-2
DoCM (Curated mutations)NKX6-2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)NKX6-2 (select a term)
intoGenNKX6-2
Cancer3DNKX6-2(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM605955   
Orphanet
DisGeNETNKX6-2
MedgenNKX6-2
Genetic Testing Registry NKX6-2
NextProtQ9C056 [Medical]
TSGene84504
GENETestsNKX6-2
Target ValidationNKX6-2
Huge Navigator NKX6-2 [HugePedia]
snp3D : Map Gene to Disease84504
BioCentury BCIQNKX6-2
ClinGenNKX6-2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD84504
Chemical/Pharm GKB GenePA134896334
Clinical trialNKX6-2
Miscellaneous
canSAR (ICR)NKX6-2 (select the gene name)
Probes
Litterature
PubMed2 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineNKX6-2
EVEXNKX6-2
GoPubMedNKX6-2
iHOPNKX6-2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Jul 30 14:19:58 CEST 2018

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.