Atlas of Genetics and Cytogenetics in Oncology and Haematology


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NLGN4Y (neuroligin 4, Y-linked)

Identity

Alias_namesneuroligin 4, Y linked
Alias_symbol (synonym)KIAA0951
Other alias-
HGNC (Hugo) NLGN4Y
LocusID (NCBI) 22829
Atlas_Id 70866
Location Yq11.221  [Link to chromosome band Yq11]
Location_base_pair Starts at 14622021 and ends at 14733549 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
NLGN4Y (Yq11.221) / TXLNGY (Yq11.222)RUNX1 (21q22.12) / NLGN4Y (Yq11.221)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)NLGN4Y   15529
Cards
Entrez_Gene (NCBI)NLGN4Y  22829  neuroligin 4, Y-linked
Aliases
GeneCards (Weizmann)NLGN4Y
Ensembl hg19 (Hinxton)ENSG00000165246 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000165246 [Gene_View]  chrY:14622021-14733549 [Contig_View]  NLGN4Y [Vega]
ICGC DataPortalENSG00000165246
TCGA cBioPortalNLGN4Y
AceView (NCBI)NLGN4Y
Genatlas (Paris)NLGN4Y
WikiGenes22829
SOURCE (Princeton)NLGN4Y
Genetics Home Reference (NIH)NLGN4Y
Genomic and cartography
GoldenPath hg38 (UCSC)NLGN4Y  -     chrY:14622021-14733549 +  Yq11.221   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)NLGN4Y  -     Yq11.221   [Description]    (hg19-Feb_2009)
EnsemblNLGN4Y - Yq11.221 [CytoView hg19]  NLGN4Y - Yq11.221 [CytoView hg38]
Mapping of homologs : NCBINLGN4Y [Mapview hg19]  NLGN4Y [Mapview hg38]
OMIM400028   
Gene and transcription
Genbank (Entrez)AA558153 AB023168 AF376804 AK295117 BC032567
RefSeq transcript (Entrez)NM_001164238 NM_001206850 NM_014893
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)NLGN4Y
Cluster EST : UnigeneHs.694600 [ NCBI ]
CGAP (NCI)Hs.694600
Alternative Splicing GalleryENSG00000165246
Gene ExpressionNLGN4Y [ NCBI-GEO ]   NLGN4Y [ EBI - ARRAY_EXPRESS ]   NLGN4Y [ SEEK ]   NLGN4Y [ MEM ]
Gene Expression Viewer (FireBrowse)NLGN4Y [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)22829
GTEX Portal (Tissue expression)NLGN4Y
Human Protein AtlasENSG00000165246-NLGN4Y [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8NFZ3   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8NFZ3  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8NFZ3
Splice isoforms : SwissVarQ8NFZ3
PhosPhoSitePlusQ8NFZ3
Domaine pattern : Prosite (Expaxy)CARBOXYLESTERASE_B_2 (PS00941)   
Domains : Interpro (EBI)AB_hydrolase    CarbesteraseB    Carboxylesterase_B_CS    Nlgn    NLGN4   
Domain families : Pfam (Sanger)COesterase (PF00135)   
Domain families : Pfam (NCBI)pfam00135   
Conserved Domain (NCBI)NLGN4Y
DMDM Disease mutations22829
Blocks (Seattle)NLGN4Y
SuperfamilyQ8NFZ3
Human Protein Atlas [tissue]ENSG00000165246-NLGN4Y [tissue]
Peptide AtlasQ8NFZ3
HPRD11849
IPIIPI00171705   IPI00240784   IPI00374695   
Protein Interaction databases
DIP (DOE-UCLA)Q8NFZ3
IntAct (EBI)Q8NFZ3
FunCoupENSG00000165246
BioGRIDNLGN4Y
STRING (EMBL)NLGN4Y
ZODIACNLGN4Y
Ontologies - Pathways
QuickGOQ8NFZ3
Ontology : AmiGOreceptor activity  protein binding  plasma membrane  integral component of plasma membrane  neuron cell-cell adhesion  synapse assembly  learning  cell surface  postsynaptic density  cell junction  social behavior  neurexin family protein binding  synapse  postsynaptic membrane  modulation of synaptic transmission  cell adhesion molecule binding  carboxylic ester hydrolase activity  vocalization behavior  scaffold protein binding  
Ontology : EGO-EBIreceptor activity  protein binding  plasma membrane  integral component of plasma membrane  neuron cell-cell adhesion  synapse assembly  learning  cell surface  postsynaptic density  cell junction  social behavior  neurexin family protein binding  synapse  postsynaptic membrane  modulation of synaptic transmission  cell adhesion molecule binding  carboxylic ester hydrolase activity  vocalization behavior  scaffold protein binding  
NDEx NetworkNLGN4Y
Atlas of Cancer Signalling NetworkNLGN4Y
Wikipedia pathwaysNLGN4Y
Orthology - Evolution
OrthoDB22829
GeneTree (enSembl)ENSG00000165246
Phylogenetic Trees/Animal Genes : TreeFamNLGN4Y
HOVERGENQ8NFZ3
HOGENOMQ8NFZ3
Homologs : HomoloGeneNLGN4Y
Homology/Alignments : Family Browser (UCSC)NLGN4Y
Gene fusions - Rearrangements
Tumor Fusion PortalNLGN4Y
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerNLGN4Y [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)NLGN4Y
dbVarNLGN4Y
ClinVarNLGN4Y
1000_GenomesNLGN4Y 
Exome Variant ServerNLGN4Y
ExAC (Exome Aggregation Consortium)ENSG00000165246
GNOMAD BrowserENSG00000165246
Genetic variants : HAPMAP22829
Genomic Variants (DGV)NLGN4Y [DGVbeta]
DECIPHERNLGN4Y [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisNLGN4Y 
Mutations
ICGC Data PortalNLGN4Y 
TCGA Data PortalNLGN4Y 
Broad Tumor PortalNLGN4Y
OASIS PortalNLGN4Y [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICNLGN4Y  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDNLGN4Y
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch NLGN4Y
DgiDB (Drug Gene Interaction Database)NLGN4Y
DoCM (Curated mutations)NLGN4Y (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)NLGN4Y (select a term)
intoGenNLGN4Y
Cancer3DNLGN4Y(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM400028   
Orphanet
DisGeNETNLGN4Y
MedgenNLGN4Y
Genetic Testing Registry NLGN4Y
NextProtQ8NFZ3 [Medical]
TSGene22829
GENETestsNLGN4Y
Target ValidationNLGN4Y
Huge Navigator NLGN4Y [HugePedia]
snp3D : Map Gene to Disease22829
BioCentury BCIQNLGN4Y
ClinGenNLGN4Y
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD22829
Chemical/Pharm GKB GenePA38386
Clinical trialNLGN4Y
Miscellaneous
canSAR (ICR)NLGN4Y (select the gene name)
Probes
Litterature
PubMed15 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineNLGN4Y
EVEXNLGN4Y
GoPubMedNLGN4Y
iHOPNLGN4Y
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Nov 21 14:01:08 CET 2017

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