NLN (neurolysin)

2014-11-01  

Identity

HGNC
LOCATION
5q12.3
LOCUSID
ALIAS
AGTBP,EP24.16,MEP,MOP
FUSION GENES

Other Information

Locus ID:

NCBI: 57486
MIM: 611530
HGNC: 16058
Ensembl: ENSG00000123213

Variants:

dbSNP: 57486
ClinVar: 57486
TCGA: ENSG00000123213
COSMIC: NLN

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000123213ENST00000380985Q9BYT8
ENSG00000123213ENST00000502464E9PCB6
ENSG00000123213ENST00000509935H0YAF7
ENSG00000123213ENST00000511299H0YAK4
ENSG00000123213ENST00000514991D6R9Y0

Expression (GTEx)

0
5
10
15
20

Pathways

PathwaySourceExternal ID
Renin-angiotensin systemKEGGko04614
Renin-angiotensin systemKEGGhsa04614
Signal TransductionREACTOMER-HSA-162582
Signaling by GPCRREACTOMER-HSA-372790
GPCR ligand bindingREACTOMER-HSA-500792
Class A/1 (Rhodopsin-like receptors)REACTOMER-HSA-373076
Peptide ligand-binding receptorsREACTOMER-HSA-375276

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
208776242010Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.17
172511852007Swapping the substrate specificities of the neuropeptidases neurolysin and thimet oligopeptidase.7
291837872018Mechanism of Peptide Binding and Cleavage by the Human Mitochondrial Peptidase Neurolysin.1

Citation

Dessen P

NLN (neurolysin)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/70868/nln