NLRP1 (NLR family, pyrin domain containing 1)

Identity

Other names	CARD7
	CLR17.1
	DEFCAP
	DEFCAP-L/S
	DKFZp586O1822
	KIAA0926
	NAC
	NALP1
	PP1044
	SLEV1
	VAMAS1
HGNC	NLRP1
Location	17p13
Location_base_pair	Starts at 5345443 and ends at 5428556 bp from pter ( according to hg18-March_2006).
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

External links

	Nomenclature
HGNC	NLRP1   14374
Entrez_Gene	NLRP1  22861  NLR family, pyrin domain containing 1
	Cards
GeneCards	NLRP1
Ensembl	NLRP1 [Search_View]   ENSG00000091592 [Gene_View]
Genatlas	NLRP1
GeneLynx	NLRP1
eGenome	NLRP1
euGene	22861
	Genomic and cartography
GoldenPath	NLRP1  -  17p13   chr17:5345443-5428556 -  17p13.2   [Description]    (hg18-March_2006)
Ensembl	NLRP1 - 17p13.2 [CytoView]
NCBI	Mapview
OMIM	Disease map [OMIM]
HomoloGene	NLRP1
	Gene and transcription
Genbank	AB023143 [ ENTREZ ]
Genbank	AF131825 [ ENTREZ ]
Genbank	AF217966 [ ENTREZ ]
Genbank	AF229059 [ ENTREZ ]
Genbank	AF229060 [ ENTREZ ]
RefSeq	NM_001033053 [ SRS ]    NM_001033053 [ ENTREZ ]
RefSeq	NM_014922 [ SRS ]    NM_014922 [ ENTREZ ]
RefSeq	NM_033004 [ SRS ]    NM_033004 [ ENTREZ ]
RefSeq	NM_033006 [ SRS ]    NM_033006 [ ENTREZ ]
RefSeq	NM_033007 [ SRS ]    NM_033007 [ ENTREZ ]
RefSeq	AC_000060 [ SRS ]    AC_000060 [ ENTREZ ]
RefSeq	AC_000149 [ SRS ]    AC_000149 [ ENTREZ ]
RefSeq	NC_000017 [ SRS ]    NC_000017 [ ENTREZ ]
RefSeq	NT_010718 [ SRS ]    NT_010718 [ ENTREZ ]
RefSeq	NW_001838403 [ SRS ]    NW_001838403 [ ENTREZ ]
RefSeq	NW_926584 [ SRS ]    NW_926584 [ ENTREZ ]
AceView	NLRP1 AceView - NCBI
Unigene	Hs.652273 [ SRS ]    Hs.652273 [ NCBI ]     HS652273 [ spliceNest ]
Fast-db	2321 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	Q86UB5 [ SRS]    Q86UB5 [ EXPASY ]     Q86UB5 [ INTERPRO ]     Q86UB5 [ UNIPROT ]
Prosite	PS50824 DAPIN [ SRS ]    PS50824 DAPIN [ Expasy ]
Prosite	PS50837 NACHT [ SRS ]    PS50837 NACHT [ Expasy ]
Interpro	IPR011029 DEATH_like [ SRS ]    IPR011029 DEATH_like [ EBI ]
Interpro	IPR000767 Disease_R [ SRS ]    IPR000767 Disease_R [ EBI ]
Interpro	IPR001611 LRR [ SRS ]    IPR001611 LRR [ EBI ]
Interpro	IPR007111 NACHT_NTPase [ SRS ]    IPR007111 NACHT_NTPase [ EBI ]
Interpro	IPR004020 Pyrin [ SRS ]    IPR004020 Pyrin [ EBI ]
CluSTr	Q86UB5
Pfam	PF00560 LRR_1 [ SRS ]    PF00560 LRR_1 [ Sanger ]    pfam00560 [ NCBI-CDD ]
Pfam	PF05729 NACHT [ SRS ]    PF05729 NACHT [ Sanger ]    pfam05729 [ NCBI-CDD ]
Pfam	PF02758 PAAD_DAPIN [ SRS ]    PF02758 PAAD_DAPIN [ Sanger ]    pfam02758 [ NCBI-CDD ]
Blocks	Q86UB5
HPRD	07364
	Protein Interaction databases
DIP	Q86UB5
IntAct	Q86UB5
	Polymorphism : SNP, mutations, diseases
OMIM	606579;606636    [ map ]
GENECLINICS	606579;606636
SNP	NLRP1 [dbSNP-NCBI]
SNP	NM_001033053 [SNP-NCI]
SNP	NM_014922 [SNP-NCI]
SNP	NM_033004 [SNP-NCI]
SNP	NM_033006 [SNP-NCI]
SNP	NM_033007 [SNP-NCI]
SNP	NLRP1 [GeneSNPs - Utah]  NLRP1] [HGBASE - SRS]
HAPMAP	NLRP1 [HAPMAP]
COSMIC	NLRP1 [Somatic mutation (COSMIC-CGP-Sanger)]
HGMD	NLRP1
	General knowledge
Family Browser	NLRP1 [UCSC Family Browser]
SOURCE	NM_001033053
SOURCE	NM_014922
SOURCE	NM_033004
SOURCE	NM_033006
SOURCE	NM_033007
SMD	Hs.652273
SAGE	Hs.652273
GO	nucleotide binding [Amigo]  nucleotide binding
GO	protein binding [Amigo]  protein binding
GO	ATP binding [Amigo]  ATP binding
GO	ATP binding [Amigo]  ATP binding
GO	intracellular [Amigo]  intracellular
GO	nucleus [Amigo]  nucleus
GO	cytoplasm [Amigo]  cytoplasm
GO	induction of apoptosis [Amigo]  induction of apoptosis
GO	caspase activation [Amigo]  caspase activation
GO	defense response [Amigo]  defense response
GO	caspase activator activity [Amigo]  caspase activator activity
GO	enzyme binding [Amigo]  enzyme binding
GO	regulation of apoptosis [Amigo]  regulation of apoptosis
GO	neuron apoptosis [Amigo]  neuron apoptosis
PubGene	NLRP1
TreeFam	NLRP1
CTD	22861 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	NLRP1 Related clones (RZPD - Berlin)
	PubMed
PubMed	26 Pubmed reference(s) in Entrez

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Tue Oct 14 20:44:52 2008