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NLRP10 (NLR family pyrin domain containing 10)

Identity

Alias_namesNALP10
NACHT, leucine rich repeat and PYD containing 10
Alias_symbol (synonym)NOD8
PAN5
Pynod
CLR11.1
Other aliasPYNOD
HGNC (Hugo) NLRP10
LocusID (NCBI) 338322
Atlas_Id 70871
Location 11p15.4  [Link to chromosome band 11p15]
Location_base_pair Starts at 7959609 and ends at 7963512 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)NLRP10   21464
Cards
Entrez_Gene (NCBI)NLRP10  338322  NLR family pyrin domain containing 10
AliasesCLR11.1; NALP10; NOD8; PAN5; 
PYNOD
GeneCards (Weizmann)NLRP10
Ensembl hg19 (Hinxton)ENSG00000182261 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000182261 [Gene_View]  chr11:7959609-7963512 [Contig_View]  NLRP10 [Vega]
ICGC DataPortalENSG00000182261
TCGA cBioPortalNLRP10
AceView (NCBI)NLRP10
Genatlas (Paris)NLRP10
WikiGenes338322
SOURCE (Princeton)NLRP10
Genetics Home Reference (NIH)NLRP10
Genomic and cartography
GoldenPath hg38 (UCSC)NLRP10  -     chr11:7959609-7963512 -  11p15.4   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)NLRP10  -     11p15.4   [Description]    (hg19-Feb_2009)
EnsemblNLRP10 - 11p15.4 [CytoView hg19]  NLRP10 - 11p15.4 [CytoView hg38]
Mapping of homologs : NCBINLRP10 [Mapview hg19]  NLRP10 [Mapview hg38]
OMIM609662   
Gene and transcription
Genbank (Entrez)AY154465 AY489192 BC104957 BK001110
RefSeq transcript (Entrez)NM_176821
RefSeq genomic (Entrez)NC_000011 NC_018922 NG_046899 NT_187583 NW_011332695
Consensus coding sequences : CCDS (NCBI)NLRP10
Cluster EST : UnigeneHs.449636 [ NCBI ]
CGAP (NCI)Hs.449636
Alternative Splicing GalleryENSG00000182261
Gene ExpressionNLRP10 [ NCBI-GEO ]   NLRP10 [ EBI - ARRAY_EXPRESS ]   NLRP10 [ SEEK ]   NLRP10 [ MEM ]
Gene Expression Viewer (FireBrowse)NLRP10 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)338322
GTEX Portal (Tissue expression)NLRP10
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ86W26   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ86W26  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ86W26
Splice isoforms : SwissVarQ86W26
PhosPhoSitePlusQ86W26
Domaine pattern : Prosite (Expaxy)DAPIN (PS50824)    NACHT (PS50837)   
Domains : Interpro (EBI)DAPIN    DEATH-like_dom    NACHT_NTPase    P-loop_NTPase   
Domain families : Pfam (Sanger)PYRIN (PF02758)   
Domain families : Pfam (NCBI)pfam02758   
Domain families : Smart (EMBL)PYRIN (SM01289)  
Conserved Domain (NCBI)NLRP10
DMDM Disease mutations338322
Blocks (Seattle)NLRP10
PDB (SRS)2M5V   
PDB (PDBSum)2M5V   
PDB (IMB)2M5V   
PDB (RSDB)2M5V   
Structural Biology KnowledgeBase2M5V   
SCOP (Structural Classification of Proteins)2M5V   
CATH (Classification of proteins structures)2M5V   
SuperfamilyQ86W26
Human Protein AtlasENSG00000182261
Peptide AtlasQ86W26
HPRD14802
IPIIPI00328970   IPI00984717   
Protein Interaction databases
DIP (DOE-UCLA)Q86W26
IntAct (EBI)Q86W26
FunCoupENSG00000182261
BioGRIDNLRP10
STRING (EMBL)NLRP10
ZODIACNLRP10
Ontologies - Pathways
QuickGOQ86W26
Ontology : AmiGOadaptive immune response  positive regulation of T-helper 1 type immune response  ATP binding  cytoplasm  extrinsic component of plasma membrane  helper T cell enhancement of adaptive immune response  dendritic cell migration  innate immune response  defense response to Gram-negative bacterium  defense response to fungus  positive regulation of T-helper 17 type immune response  positive regulation of interleukin-8 secretion  positive regulation of interleukin-6 secretion  
Ontology : EGO-EBIadaptive immune response  positive regulation of T-helper 1 type immune response  ATP binding  cytoplasm  extrinsic component of plasma membrane  helper T cell enhancement of adaptive immune response  dendritic cell migration  innate immune response  defense response to Gram-negative bacterium  defense response to fungus  positive regulation of T-helper 17 type immune response  positive regulation of interleukin-8 secretion  positive regulation of interleukin-6 secretion  
NDEx NetworkNLRP10
Atlas of Cancer Signalling NetworkNLRP10
Wikipedia pathwaysNLRP10
Orthology - Evolution
OrthoDB338322
GeneTree (enSembl)ENSG00000182261
Phylogenetic Trees/Animal Genes : TreeFamNLRP10
HOVERGENQ86W26
HOGENOMQ86W26
Homologs : HomoloGeneNLRP10
Homology/Alignments : Family Browser (UCSC)NLRP10
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerNLRP10 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)NLRP10
dbVarNLRP10
ClinVarNLRP10
1000_GenomesNLRP10 
Exome Variant ServerNLRP10
ExAC (Exome Aggregation Consortium)NLRP10 (select the gene name)
Genetic variants : HAPMAP338322
Genomic Variants (DGV)NLRP10 [DGVbeta]
DECIPHERNLRP10 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisNLRP10 
Mutations
ICGC Data PortalNLRP10 
TCGA Data PortalNLRP10 
Broad Tumor PortalNLRP10
OASIS PortalNLRP10 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICNLRP10  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDNLRP10
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch NLRP10
DgiDB (Drug Gene Interaction Database)NLRP10
DoCM (Curated mutations)NLRP10 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)NLRP10 (select a term)
intoGenNLRP10
Cancer3DNLRP10(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM609662   
Orphanet
MedgenNLRP10
Genetic Testing Registry NLRP10
NextProtQ86W26 [Medical]
TSGene338322
GENETestsNLRP10
Target ValidationNLRP10
Huge Navigator NLRP10 [HugePedia]
snp3D : Map Gene to Disease338322
BioCentury BCIQNLRP10
ClinGenNLRP10
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD338322
Chemical/Pharm GKB GenePA162397832
Clinical trialNLRP10
Miscellaneous
canSAR (ICR)NLRP10 (select the gene name)
Probes
Litterature
PubMed15 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineNLRP10
EVEXNLRP10
GoPubMedNLRP10
iHOPNLRP10
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed May 31 15:32:46 CEST 2017

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