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NLRP14 (NLR family pyrin domain containing 14)

Identity

Alias_namesNALP14
NACHT, leucine rich repeat and PYD containing 14
Alias_symbol (synonym)NOD5
GC-LRR
Nalp-iota
PAN8
CLR11.2
Other alias
HGNC (Hugo) NLRP14
LocusID (NCBI) 338323
Atlas_Id 70875
Location 11p15.4  [Link to chromosome band 11p15]
Location_base_pair Starts at 7020469 and ends at 7071526 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
NEUROD2 (17q12) / NLRP14 (11p15.4)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)NLRP14   22939
Cards
Entrez_Gene (NCBI)NLRP14  338323  NLR family pyrin domain containing 14
AliasesCLR11.2; GC-LRR; NALP14; NOD5; 
PAN8
GeneCards (Weizmann)NLRP14
Ensembl hg19 (Hinxton)ENSG00000158077 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000158077 [Gene_View]  chr11:7020469-7071526 [Contig_View]  NLRP14 [Vega]
ICGC DataPortalENSG00000158077
TCGA cBioPortalNLRP14
AceView (NCBI)NLRP14
Genatlas (Paris)NLRP14
WikiGenes338323
SOURCE (Princeton)NLRP14
Genetics Home Reference (NIH)NLRP14
Genomic and cartography
GoldenPath hg38 (UCSC)NLRP14  -     chr11:7020469-7071526 +  11p15.4   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)NLRP14  -     11p15.4   [Description]    (hg19-Feb_2009)
EnsemblNLRP14 - 11p15.4 [CytoView hg19]  NLRP14 - 11p15.4 [CytoView hg38]
Mapping of homologs : NCBINLRP14 [Mapview hg19]  NLRP14 [Mapview hg38]
OMIM609665   
Gene and transcription
Genbank (Entrez)AK310900 AY154469 BC156268 BK001107 DB226777
RefSeq transcript (Entrez)NM_176822
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)NLRP14
Cluster EST : UnigeneHs.449637 [ NCBI ]
CGAP (NCI)Hs.449637
Alternative Splicing GalleryENSG00000158077
Gene ExpressionNLRP14 [ NCBI-GEO ]   NLRP14 [ EBI - ARRAY_EXPRESS ]   NLRP14 [ SEEK ]   NLRP14 [ MEM ]
Gene Expression Viewer (FireBrowse)NLRP14 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)338323
GTEX Portal (Tissue expression)NLRP14
Human Protein AtlasENSG00000158077-NLRP14 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ86W24   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ86W24  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ86W24
Splice isoforms : SwissVarQ86W24
PhosPhoSitePlusQ86W24
Domaine pattern : Prosite (Expaxy)DAPIN (PS50824)    NACHT (PS50837)   
Domains : Interpro (EBI)DAPIN    DEATH-like_dom    L_dom-like    Leu-rich_rpt    NACHT_NTPase    P-loop_NTPase   
Domain families : Pfam (Sanger)LRR_6 (PF13516)    PYRIN (PF02758)   
Domain families : Pfam (NCBI)pfam13516    pfam02758   
Domain families : Smart (EMBL)PYRIN (SM01289)  
Conserved Domain (NCBI)NLRP14
DMDM Disease mutations338323
Blocks (Seattle)NLRP14
PDB (SRS)4N1J    4N1K    4N1L   
PDB (PDBSum)4N1J    4N1K    4N1L   
PDB (IMB)4N1J    4N1K    4N1L   
PDB (RSDB)4N1J    4N1K    4N1L   
Structural Biology KnowledgeBase4N1J    4N1K    4N1L   
SCOP (Structural Classification of Proteins)4N1J    4N1K    4N1L   
CATH (Classification of proteins structures)4N1J    4N1K    4N1L   
SuperfamilyQ86W24
Human Protein Atlas [tissue]ENSG00000158077-NLRP14 [tissue]
Peptide AtlasQ86W24
HPRD11383
IPIIPI00219561   
Protein Interaction databases
DIP (DOE-UCLA)Q86W24
IntAct (EBI)Q86W24
FunCoupENSG00000158077
BioGRIDNLRP14
STRING (EMBL)NLRP14
ZODIACNLRP14
Ontologies - Pathways
QuickGOQ86W24
Ontology : AmiGOATP binding  multicellular organism development  spermatogenesis  cell differentiation  
Ontology : EGO-EBIATP binding  multicellular organism development  spermatogenesis  cell differentiation  
NDEx NetworkNLRP14
Atlas of Cancer Signalling NetworkNLRP14
Wikipedia pathwaysNLRP14
Orthology - Evolution
OrthoDB338323
GeneTree (enSembl)ENSG00000158077
Phylogenetic Trees/Animal Genes : TreeFamNLRP14
HOVERGENQ86W24
HOGENOMQ86W24
Homologs : HomoloGeneNLRP14
Homology/Alignments : Family Browser (UCSC)NLRP14
Gene fusions - Rearrangements
Tumor Fusion PortalNLRP14
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerNLRP14 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)NLRP14
dbVarNLRP14
ClinVarNLRP14
1000_GenomesNLRP14 
Exome Variant ServerNLRP14
ExAC (Exome Aggregation Consortium)ENSG00000158077
GNOMAD BrowserENSG00000158077
Genetic variants : HAPMAP338323
Genomic Variants (DGV)NLRP14 [DGVbeta]
DECIPHERNLRP14 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisNLRP14 
Mutations
ICGC Data PortalNLRP14 
TCGA Data PortalNLRP14 
Broad Tumor PortalNLRP14
OASIS PortalNLRP14 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICNLRP14  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDNLRP14
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch NLRP14
DgiDB (Drug Gene Interaction Database)NLRP14
DoCM (Curated mutations)NLRP14 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)NLRP14 (select a term)
intoGenNLRP14
Cancer3DNLRP14(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM609665   
Orphanet
DisGeNETNLRP14
MedgenNLRP14
Genetic Testing Registry NLRP14
NextProtQ86W24 [Medical]
TSGene338323
GENETestsNLRP14
Target ValidationNLRP14
Huge Navigator NLRP14 [HugePedia]
snp3D : Map Gene to Disease338323
BioCentury BCIQNLRP14
ClinGenNLRP14
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD338323
Chemical/Pharm GKB GenePA162397917
Clinical trialNLRP14
Miscellaneous
canSAR (ICR)NLRP14 (select the gene name)
Probes
Litterature
PubMed10 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineNLRP14
EVEXNLRP14
GoPubMedNLRP14
iHOPNLRP14
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Nov 21 13:24:16 CET 2017

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