Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

NLRP2B (NLR family pyrin domain containing 2B)

Identity

Alias_namesNLRP2P
NLR family
Alias_symbol (synonym)NOD24
NALP2P
CLRX.1
POP4
Other alias
HGNC (Hugo) NLRP2B
LocusID (NCBI) 286430
Atlas_Id 55808
Location Xp11.21  [Link to chromosome band Xp11]
Location_base_pair Starts at 57677067 and ends at 57680260 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)NLRP2B   29887
Cards
Entrez_Gene (NCBI)NLRP2B  286430  NLR family pyrin domain containing 2B
AliasesCLRX.1; NALP2P; NLRP2P; NOD24; 
POP4
GeneCards (Weizmann)NLRP2B
Ensembl hg19 (Hinxton) [Gene_View]
Ensembl hg38 (Hinxton) [Gene_View]  chrX:57677067-57680260 [Contig_View]  NLRP2B [Vega]
TCGA cBioPortalNLRP2B
AceView (NCBI)NLRP2B
Genatlas (Paris)NLRP2B
WikiGenes286430
SOURCE (Princeton)NLRP2B
Genetics Home Reference (NIH)NLRP2B
Genomic and cartography
GoldenPath hg38 (UCSC)NLRP2B  -     chrX:57677067-57680260 -  Xp11.21   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)NLRP2B  -     Xp11.21   [Description]    (hg19-Feb_2009)
EnsemblNLRP2B - Xp11.21 [CytoView hg19]  NLRP2B - Xp11.21 [CytoView hg38]
Mapping of homologs : NCBINLRP2B [Mapview hg19]  NLRP2B [Mapview hg38]
Gene and transcription
Genbank (Entrez)AK026387
RefSeq transcript (Entrez)NM_001319967
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)NLRP2B
Cluster EST : UnigeneHs.306842 [ NCBI ]
CGAP (NCI)Hs.306842
Gene ExpressionNLRP2B [ NCBI-GEO ]   NLRP2B [ EBI - ARRAY_EXPRESS ]   NLRP2B [ SEEK ]   NLRP2B [ MEM ]
Gene Expression Viewer (FireBrowse)NLRP2B [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)286430
GTEX Portal (Tissue expression)NLRP2B
Protein : pattern, domain, 3D structure
UniProt/SwissProtP0DMW2   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP0DMW2  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP0DMW2
Splice isoforms : SwissVarP0DMW2
PhosPhoSitePlusP0DMW2
Domains : Interpro (EBI)DEATH-like_dom   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Conserved Domain (NCBI)NLRP2B
DMDM Disease mutations286430
Blocks (Seattle)NLRP2B
SuperfamilyP0DMW2
Peptide AtlasP0DMW2
Protein Interaction databases
DIP (DOE-UCLA)P0DMW2
IntAct (EBI)P0DMW2
BioGRIDNLRP2B
STRING (EMBL)NLRP2B
ZODIACNLRP2B
Ontologies - Pathways
QuickGOP0DMW2
Ontology : AmiGOnucleus  cytoplasm  negative regulation of tumor necrosis factor-mediated signaling pathway  negative regulation of NF-kappaB transcription factor activity  negative regulation of peptidyl-serine phosphorylation  negative regulation of toll-like receptor signaling pathway  positive regulation of apoptotic process  innate immune response  negative regulation of cell cycle  negative regulation of interleukin-1 beta secretion  negative regulation of NLRP3 inflammasome complex assembly  
Ontology : EGO-EBInucleus  cytoplasm  negative regulation of tumor necrosis factor-mediated signaling pathway  negative regulation of NF-kappaB transcription factor activity  negative regulation of peptidyl-serine phosphorylation  negative regulation of toll-like receptor signaling pathway  positive regulation of apoptotic process  innate immune response  negative regulation of cell cycle  negative regulation of interleukin-1 beta secretion  negative regulation of NLRP3 inflammasome complex assembly  
NDEx NetworkNLRP2B
Atlas of Cancer Signalling NetworkNLRP2B
Wikipedia pathwaysNLRP2B
Orthology - Evolution
OrthoDB286430
Phylogenetic Trees/Animal Genes : TreeFamNLRP2B
HOVERGENP0DMW2
HOGENOMP0DMW2
Homologs : HomoloGeneNLRP2B
Homology/Alignments : Family Browser (UCSC)NLRP2B
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerNLRP2B [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)NLRP2B
dbVarNLRP2B
ClinVarNLRP2B
1000_GenomesNLRP2B 
Exome Variant ServerNLRP2B
ExAC (Exome Aggregation Consortium)NLRP2B (select the gene name)
Genetic variants : HAPMAP286430
Genomic Variants (DGV)NLRP2B [DGVbeta]
DECIPHERNLRP2B [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisNLRP2B 
Mutations
ICGC Data PortalNLRP2B 
TCGA Data PortalNLRP2B 
Broad Tumor PortalNLRP2B
OASIS PortalNLRP2B [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDNLRP2B
BioMutasearch NLRP2B
DgiDB (Drug Gene Interaction Database)NLRP2B
DoCM (Curated mutations)NLRP2B (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)NLRP2B (select a term)
intoGenNLRP2B
Cancer3DNLRP2B(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenNLRP2B
Genetic Testing Registry NLRP2B
NextProtP0DMW2 [Medical]
TSGene286430
GENETestsNLRP2B
Target ValidationNLRP2B
Huge Navigator NLRP2B [HugePedia]
snp3D : Map Gene to Disease286430
BioCentury BCIQNLRP2B
ClinGenNLRP2B
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD286430
Clinical trialNLRP2B
Miscellaneous
canSAR (ICR)NLRP2B (select the gene name)
Probes
Litterature
PubMed3 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineNLRP2B
EVEXNLRP2B
GoPubMedNLRP2B
iHOPNLRP2B
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Jun 7 12:46:58 CEST 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.