Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

NLRX1 (NLR family member X1)

Identity

Alias_symbol (synonym)NOD9
CLR11.3
Other aliasDLNB26
NOD26
NOD5
HGNC (Hugo) NLRX1
LocusID (NCBI) 79671
Atlas_Id 55406
Location 11q23.3  [Link to chromosome band 11q23]
Location_base_pair Starts at 119168713 and ends at 119184016 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
NLRX1 (11q23.3) / NLRX1 (11q23.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)NLRX1   29890
Cards
Entrez_Gene (NCBI)NLRX1  79671  NLR family member X1
AliasesCLR11.3; DLNB26; NOD26; NOD5; 
NOD9
GeneCards (Weizmann)NLRX1
Ensembl hg19 (Hinxton)ENSG00000160703 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000160703 [Gene_View]  chr11:119168713-119184016 [Contig_View]  NLRX1 [Vega]
ICGC DataPortalENSG00000160703
TCGA cBioPortalNLRX1
AceView (NCBI)NLRX1
Genatlas (Paris)NLRX1
WikiGenes79671
SOURCE (Princeton)NLRX1
Genetics Home Reference (NIH)NLRX1
Genomic and cartography
GoldenPath hg38 (UCSC)NLRX1  -     chr11:119168713-119184016 +  11q23.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)NLRX1  -     11q23.3   [Description]    (hg19-Feb_2009)
EnsemblNLRX1 - 11q23.3 [CytoView hg19]  NLRX1 - 11q23.3 [CytoView hg38]
Mapping of homologs : NCBINLRX1 [Mapview hg19]  NLRX1 [Mapview hg38]
OMIM611947   
Gene and transcription
Genbank (Entrez)AB094095 AK025131 AK056454 AK095247 AK225223
RefSeq transcript (Entrez)NM_001282143 NM_001282144 NM_001282358 NM_024618 NM_170722
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)NLRX1
Cluster EST : UnigeneHs.524082 [ NCBI ]
CGAP (NCI)Hs.524082
Alternative Splicing GalleryENSG00000160703
Gene ExpressionNLRX1 [ NCBI-GEO ]   NLRX1 [ EBI - ARRAY_EXPRESS ]   NLRX1 [ SEEK ]   NLRX1 [ MEM ]
Gene Expression Viewer (FireBrowse)NLRX1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)79671
GTEX Portal (Tissue expression)NLRX1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ86UT6   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ86UT6  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ86UT6
Splice isoforms : SwissVarQ86UT6
PhosPhoSitePlusQ86UT6
Domaine pattern : Prosite (Expaxy)NACHT (PS50837)   
Domains : Interpro (EBI)L_dom-like    Leu-rich_rpt    NACHT_NTPase   
Domain families : Pfam (Sanger)LRR_6 (PF13516)   
Domain families : Pfam (NCBI)pfam13516   
Conserved Domain (NCBI)NLRX1
DMDM Disease mutations79671
Blocks (Seattle)NLRX1
PDB (SRS)3UN9   
PDB (PDBSum)3UN9   
PDB (IMB)3UN9   
PDB (RSDB)3UN9   
Structural Biology KnowledgeBase3UN9   
SCOP (Structural Classification of Proteins)3UN9   
CATH (Classification of proteins structures)3UN9   
SuperfamilyQ86UT6
Human Protein AtlasENSG00000160703
Peptide AtlasQ86UT6
HPRD17640
IPIIPI00465264   IPI00377214   IPI00470424   IPI00916374   IPI00916778   IPI00916130   
Protein Interaction databases
DIP (DOE-UCLA)Q86UT6
IntAct (EBI)Q86UT6
FunCoupENSG00000160703
BioGRIDNLRX1
STRING (EMBL)NLRX1
ZODIACNLRX1
Ontologies - Pathways
QuickGOQ86UT6
Ontology : AmiGOprotein binding  ATP binding  mitochondrion  mitochondrial outer membrane  plasma membrane  viral process  cell junction  negative regulation of type I interferon production  negative regulation of interferon-beta production  negative regulation of interleukin-6 production  negative regulation of RIG-I signaling pathway  negative regulation of I-kappaB kinase/NF-kappaB signaling  innate immune response  negative regulation of innate immune response  negative regulation of inflammatory response  
Ontology : EGO-EBIprotein binding  ATP binding  mitochondrion  mitochondrial outer membrane  plasma membrane  viral process  cell junction  negative regulation of type I interferon production  negative regulation of interferon-beta production  negative regulation of interleukin-6 production  negative regulation of RIG-I signaling pathway  negative regulation of I-kappaB kinase/NF-kappaB signaling  innate immune response  negative regulation of innate immune response  negative regulation of inflammatory response  
Pathways : KEGGRIG-I-like receptor signaling pathway    Influenza A   
NDEx NetworkNLRX1
Atlas of Cancer Signalling NetworkNLRX1
Wikipedia pathwaysNLRX1
Orthology - Evolution
OrthoDB79671
GeneTree (enSembl)ENSG00000160703
Phylogenetic Trees/Animal Genes : TreeFamNLRX1
HOVERGENQ86UT6
HOGENOMQ86UT6
Homologs : HomoloGeneNLRX1
Homology/Alignments : Family Browser (UCSC)NLRX1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerNLRX1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)NLRX1
dbVarNLRX1
ClinVarNLRX1
1000_GenomesNLRX1 
Exome Variant ServerNLRX1
ExAC (Exome Aggregation Consortium)NLRX1 (select the gene name)
Genetic variants : HAPMAP79671
Genomic Variants (DGV)NLRX1 [DGVbeta]
DECIPHERNLRX1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisNLRX1 
Mutations
ICGC Data PortalNLRX1 
TCGA Data PortalNLRX1 
Broad Tumor PortalNLRX1
OASIS PortalNLRX1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICNLRX1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDNLRX1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch NLRX1
DgiDB (Drug Gene Interaction Database)NLRX1
DoCM (Curated mutations)NLRX1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)NLRX1 (select a term)
intoGenNLRX1
Cancer3DNLRX1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM611947   
Orphanet
MedgenNLRX1
Genetic Testing Registry NLRX1
NextProtQ86UT6 [Medical]
TSGene79671
GENETestsNLRX1
Target ValidationNLRX1
Huge Navigator NLRX1 [HugePedia]
snp3D : Map Gene to Disease79671
BioCentury BCIQNLRX1
ClinGenNLRX1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD79671
Chemical/Pharm GKB GenePA162398052
Clinical trialNLRX1
Miscellaneous
canSAR (ICR)NLRX1 (select the gene name)
Probes
Litterature
PubMed29 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineNLRX1
EVEXNLRX1
GoPubMedNLRX1
iHOPNLRX1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Sep 18 14:01:43 CEST 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.