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NME6 (NME/NM23 nucleoside diphosphate kinase 6)

Identity

Alias_namesnon-metastatic cells 6
Alias_symbol (synonym)NM23-H6
IPIA-ALPHA
Other aliasNDK 6
HGNC (Hugo) NME6
LocusID (NCBI) 10201
Atlas_Id 41547
Location 3p21.31  [Link to chromosome band 3p21]
Location_base_pair Starts at 48292317 and ends at 48301685 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)NME6   20567
Cards
Entrez_Gene (NCBI)NME6  10201  NME/NM23 nucleoside diphosphate kinase 6
AliasesIPIA-ALPHA; NDK; NM23-H6
GeneCards (Weizmann)NME6
Ensembl hg19 (Hinxton)ENSG00000172113 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000172113 [Gene_View]  chr3:48292317-48301685 [Contig_View]  NME6 [Vega]
ICGC DataPortalENSG00000172113
TCGA cBioPortalNME6
AceView (NCBI)NME6
Genatlas (Paris)NME6
WikiGenes10201
SOURCE (Princeton)NME6
Genetics Home Reference (NIH)NME6
Genomic and cartography
GoldenPath hg38 (UCSC)NME6  -     chr3:48292317-48301685 -  3p21.31   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)NME6  -     3p21.31   [Description]    (hg19-Feb_2009)
EnsemblNME6 - 3p21.31 [CytoView hg19]  NME6 - 3p21.31 [CytoView hg38]
Mapping of homologs : NCBINME6 [Mapview hg19]  NME6 [Mapview hg38]
OMIM608294   
Gene and transcription
Genbank (Entrez)AF051941 AK222555 AK294809 AK297364 AK308970
RefSeq transcript (Entrez)NM_001308426 NM_001308427 NM_001308428 NM_001308430 NM_001308431 NM_001308433 NM_001308434 NM_001308435 NM_005793
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)NME6
Cluster EST : UnigeneHs.638192 [ NCBI ]
CGAP (NCI)Hs.638192
Alternative Splicing GalleryENSG00000172113
Gene ExpressionNME6 [ NCBI-GEO ]   NME6 [ EBI - ARRAY_EXPRESS ]   NME6 [ SEEK ]   NME6 [ MEM ]
Gene Expression Viewer (FireBrowse)NME6 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)10201
GTEX Portal (Tissue expression)NME6
Protein : pattern, domain, 3D structure
UniProt/SwissProtO75414   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO75414  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO75414
Splice isoforms : SwissVarO75414
Catalytic activity : Enzyme2.7.4.6 [ Enzyme-Expasy ]   2.7.4.62.7.4.6 [ IntEnz-EBI ]   2.7.4.6 [ BRENDA ]   2.7.4.6 [ KEGG ]   
PhosPhoSitePlusO75414
Domaine pattern : Prosite (Expaxy)NDP_KINASES (PS00469)   
Domains : Interpro (EBI)Nucleoside_diP_kinase    Nucleoside_diP_kinase_AS   
Domain families : Pfam (Sanger)NDK (PF00334)   
Domain families : Pfam (NCBI)pfam00334   
Domain families : Smart (EMBL)NDK (SM00562)  
Conserved Domain (NCBI)NME6
DMDM Disease mutations10201
Blocks (Seattle)NME6
SuperfamilyO75414
Human Protein AtlasENSG00000172113
Peptide AtlasO75414
HPRD09219
IPIIPI00218214   IPI00910598   IPI00910570   IPI01009463   IPI00927005   IPI00924760   IPI00927746   IPI00924527   IPI00797290   
Protein Interaction databases
DIP (DOE-UCLA)O75414
IntAct (EBI)O75414
FunCoupENSG00000172113
BioGRIDNME6
STRING (EMBL)NME6
ZODIACNME6
Ontologies - Pathways
QuickGOO75414
Ontology : AmiGOnucleoside diphosphate kinase activity  ATP binding  mitochondrion  nucleoside diphosphate phosphorylation  GTP biosynthetic process  UTP biosynthetic process  CTP biosynthetic process  apoptotic process  negative regulation of cell growth  negative regulation of mitotic nuclear division  metal ion binding  
Ontology : EGO-EBInucleoside diphosphate kinase activity  ATP binding  mitochondrion  nucleoside diphosphate phosphorylation  GTP biosynthetic process  UTP biosynthetic process  CTP biosynthetic process  apoptotic process  negative regulation of cell growth  negative regulation of mitotic nuclear division  metal ion binding  
Pathways : KEGGPurine metabolism    Pyrimidine metabolism   
NDEx NetworkNME6
Atlas of Cancer Signalling NetworkNME6
Wikipedia pathwaysNME6
Orthology - Evolution
OrthoDB10201
GeneTree (enSembl)ENSG00000172113
Phylogenetic Trees/Animal Genes : TreeFamNME6
HOVERGENO75414
HOGENOMO75414
Homologs : HomoloGeneNME6
Homology/Alignments : Family Browser (UCSC)NME6
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerNME6 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)NME6
dbVarNME6
ClinVarNME6
1000_GenomesNME6 
Exome Variant ServerNME6
ExAC (Exome Aggregation Consortium)NME6 (select the gene name)
Genetic variants : HAPMAP10201
Genomic Variants (DGV)NME6 [DGVbeta]
DECIPHERNME6 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisNME6 
Mutations
ICGC Data PortalNME6 
TCGA Data PortalNME6 
Broad Tumor PortalNME6
OASIS PortalNME6 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICNME6  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDNME6
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch NME6
DgiDB (Drug Gene Interaction Database)NME6
DoCM (Curated mutations)NME6 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)NME6 (select a term)
intoGenNME6
Cancer3DNME6(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM608294   
Orphanet
MedgenNME6
Genetic Testing Registry NME6
NextProtO75414 [Medical]
TSGene10201
GENETestsNME6
Target ValidationNME6
Huge Navigator NME6 [HugePedia]
snp3D : Map Gene to Disease10201
BioCentury BCIQNME6
ClinGenNME6
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD10201
Chemical/Pharm GKB GenePA134873104
Clinical trialNME6
Miscellaneous
canSAR (ICR)NME6 (select the gene name)
Probes
Litterature
PubMed14 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineNME6
EVEXNME6
GoPubMedNME6
iHOPNME6
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Aug 1 17:09:12 CEST 2017

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