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NME8 (NME/NM23 family member 8)

Identity

Alias_namesTXNDC3
thioredoxin domain containing 3 (spermatozoa)
Alias_symbol (synonym)CILD6
SPTRX2
NM23-H8
Other aliassptrx-2
HGNC (Hugo) NME8
LocusID (NCBI) 51314
Atlas_Id 70886
Location 7p14.1  [Link to chromosome band 7p14]
Location_base_pair Starts at 37888199 and ends at 37940002 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)NME8   16473
Cards
Entrez_Gene (NCBI)NME8  51314  NME/NM23 family member 8
AliasesCILD6; NM23-H8; SPTRX2; TXNDC3; 
sptrx-2
GeneCards (Weizmann)NME8
Ensembl hg19 (Hinxton)ENSG00000086288 [Gene_View]  chr7:37888199-37940002 [Contig_View]  NME8 [Vega]
Ensembl hg38 (Hinxton)ENSG00000086288 [Gene_View]  chr7:37888199-37940002 [Contig_View]  NME8 [Vega]
ICGC DataPortalENSG00000086288
TCGA cBioPortalNME8
AceView (NCBI)NME8
Genatlas (Paris)NME8
WikiGenes51314
SOURCE (Princeton)NME8
Genetics Home Reference (NIH)NME8
Genomic and cartography
GoldenPath hg19 (UCSC)NME8  -     chr7:37888199-37940002 +  7p14.1   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)NME8  -     7p14.1   [Description]    (hg38-Dec_2013)
EnsemblNME8 - 7p14.1 [CytoView hg19]  NME8 - 7p14.1 [CytoView hg38]
Mapping of homologs : NCBINME8 [Mapview hg19]  NME8 [Mapview hg38]
OMIM607421   610852   
Gene and transcription
Genbank (Entrez)AF202051 AF305596 AK313599 BC036816 JF432242
RefSeq transcript (Entrez)NM_016616
RefSeq genomic (Entrez)NC_000007 NC_018918 NG_015893 NT_007819 NW_004929329
Consensus coding sequences : CCDS (NCBI)NME8
Cluster EST : UnigeneHs.723454 [ NCBI ]
CGAP (NCI)Hs.723454
Alternative Splicing GalleryENSG00000086288
Gene ExpressionNME8 [ NCBI-GEO ]   NME8 [ EBI - ARRAY_EXPRESS ]   NME8 [ SEEK ]   NME8 [ MEM ]
Gene Expression Viewer (FireBrowse)NME8 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)51314
GTEX Portal (Tissue expression)NME8
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8N427   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8N427  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8N427
Splice isoforms : SwissVarQ8N427
PhosPhoSitePlusQ8N427
Domaine pattern : Prosite (Expaxy)THIOREDOXIN_1 (PS00194)    THIOREDOXIN_2 (PS51352)   
Domains : Interpro (EBI)Nucleoside_diP_kinase    Thioredoxin-like_fold    Thioredoxin_CS    Thioredoxin_domain   
Domain families : Pfam (Sanger)NDK (PF00334)    Thioredoxin (PF00085)   
Domain families : Pfam (NCBI)pfam00334    pfam00085   
Domain families : Smart (EMBL)NDK (SM00562)  
Conserved Domain (NCBI)NME8
DMDM Disease mutations51314
Blocks (Seattle)NME8
SuperfamilyQ8N427
Human Protein AtlasENSG00000086288
Peptide AtlasQ8N427
HPRD16243
IPIIPI00296545   IPI00927893   IPI00926242   IPI00926507   
Protein Interaction databases
DIP (DOE-UCLA)Q8N427
IntAct (EBI)Q8N427
FunCoupENSG00000086288
BioGRIDNME8
STRING (EMBL)NME8
ZODIACNME8
Ontologies - Pathways
QuickGOQ8N427
Ontology : AmiGOnucleoside diphosphate kinase activity  ATP binding  intracellular  nucleoside diphosphate phosphorylation  GTP biosynthetic process  UTP biosynthetic process  CTP biosynthetic process  multicellular organismal development  spermatogenesis  microtubule binding  cell differentiation  outer dynein arm  cilium assembly  cell redox homeostasis  
Ontology : EGO-EBInucleoside diphosphate kinase activity  ATP binding  intracellular  nucleoside diphosphate phosphorylation  GTP biosynthetic process  UTP biosynthetic process  CTP biosynthetic process  multicellular organismal development  spermatogenesis  microtubule binding  cell differentiation  outer dynein arm  cilium assembly  cell redox homeostasis  
NDEx NetworkNME8
Atlas of Cancer Signalling NetworkNME8
Wikipedia pathwaysNME8
Orthology - Evolution
OrthoDB51314
GeneTree (enSembl)ENSG00000086288
Phylogenetic Trees/Animal Genes : TreeFamNME8
HOVERGENQ8N427
HOGENOMQ8N427
Homologs : HomoloGeneNME8
Homology/Alignments : Family Browser (UCSC)NME8
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerNME8 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)NME8
dbVarNME8
ClinVarNME8
1000_GenomesNME8 
Exome Variant ServerNME8
ExAC (Exome Aggregation Consortium)NME8 (select the gene name)
Genetic variants : HAPMAP51314
Genomic Variants (DGV)NME8 [DGVbeta]
DECIPHER (Syndromes)7:37888199-37940002  ENSG00000086288
CONAN: Copy Number AnalysisNME8 
Mutations
ICGC Data PortalNME8 
TCGA Data PortalNME8 
Broad Tumor PortalNME8
OASIS PortalNME8 [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDNME8
BioMutasearch NME8
DgiDB (Drug Gene Interaction Database)NME8
DoCM (Curated mutations)NME8 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)NME8 (select a term)
intoGenNME8
Cancer3DNME8(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM607421    610852   
Orphanet665   
MedgenNME8
Genetic Testing Registry NME8
NextProtQ8N427 [Medical]
TSGene51314
GENETestsNME8
Huge Navigator NME8 [HugePedia]
snp3D : Map Gene to Disease51314
BioCentury BCIQNME8
ClinGenNME8
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD51314
Chemical/Pharm GKB GenePA134925065
Clinical trialNME8
Miscellaneous
canSAR (ICR)NME8 (select the gene name)
Probes
Litterature
PubMed17 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineNME8
EVEXNME8
GoPubMedNME8
iHOPNME8
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 12:35:04 CET 2017

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