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NMNAT3 (nicotinamide nucleotide adenylyltransferase 3)

Identity

Alias_symbol (synonym)PNAT3
Other aliasFKSG76
PNAT-3
HGNC (Hugo) NMNAT3
LocusID (NCBI) 349565
Atlas_Id 70887
Location 3q23  [Link to chromosome band 3q23]
Location_base_pair Starts at 139560181 and ends at 139678050 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
CCDC36 (3p21.31) / NMNAT3 (3q23)CLASP2 (3p22.3) / NMNAT3 (3q23)MAG (19q13.12) / NMNAT3 (3q23)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)NMNAT3   20989
Cards
Entrez_Gene (NCBI)NMNAT3  349565  nicotinamide nucleotide adenylyltransferase 3
AliasesFKSG76; PNAT-3; PNAT3
GeneCards (Weizmann)NMNAT3
Ensembl hg19 (Hinxton)ENSG00000163864 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000163864 [Gene_View]  chr3:139560181-139678050 [Contig_View]  NMNAT3 [Vega]
ICGC DataPortalENSG00000163864
TCGA cBioPortalNMNAT3
AceView (NCBI)NMNAT3
Genatlas (Paris)NMNAT3
WikiGenes349565
SOURCE (Princeton)NMNAT3
Genetics Home Reference (NIH)NMNAT3
Genomic and cartography
GoldenPath hg38 (UCSC)NMNAT3  -     chr3:139560181-139678050 -  3q23   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)NMNAT3  -     3q23   [Description]    (hg19-Feb_2009)
EnsemblNMNAT3 - 3q23 [CytoView hg19]  NMNAT3 - 3q23 [CytoView hg38]
Mapping of homologs : NCBINMNAT3 [Mapview hg19]  NMNAT3 [Mapview hg38]
OMIM608702   
Gene and transcription
Genbank (Entrez)AA894638 AF345564 AK123208 AK127477 BC034374
RefSeq transcript (Entrez)NM_001200047 NM_001320510 NM_001320511 NM_001320512 NM_001320513 NM_178177
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)NMNAT3
Cluster EST : UnigeneHs.745268 [ NCBI ]
CGAP (NCI)Hs.745268
Alternative Splicing GalleryENSG00000163864
Gene ExpressionNMNAT3 [ NCBI-GEO ]   NMNAT3 [ EBI - ARRAY_EXPRESS ]   NMNAT3 [ SEEK ]   NMNAT3 [ MEM ]
Gene Expression Viewer (FireBrowse)NMNAT3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)349565
GTEX Portal (Tissue expression)NMNAT3
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96T66   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96T66  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96T66
Splice isoforms : SwissVarQ96T66
Catalytic activity : Enzyme2.7.7.18 [ Enzyme-Expasy ]   2.7.7.182.7.7.18 [ IntEnz-EBI ]   2.7.7.18 [ BRENDA ]   2.7.7.18 [ KEGG ]   
PhosPhoSitePlusQ96T66
Domains : Interpro (EBI)Cyt_trans-like    NadD/NMNAT    Rossmann-like_a/b/a_fold   
Domain families : Pfam (Sanger)CTP_transf_like (PF01467)   
Domain families : Pfam (NCBI)pfam01467   
Conserved Domain (NCBI)NMNAT3
DMDM Disease mutations349565
Blocks (Seattle)NMNAT3
PDB (SRS)1NUP    1NUQ    1NUR    1NUS    1NUT    1NUU   
PDB (PDBSum)1NUP    1NUQ    1NUR    1NUS    1NUT    1NUU   
PDB (IMB)1NUP    1NUQ    1NUR    1NUS    1NUT    1NUU   
PDB (RSDB)1NUP    1NUQ    1NUR    1NUS    1NUT    1NUU   
Structural Biology KnowledgeBase1NUP    1NUQ    1NUR    1NUS    1NUT    1NUU   
SCOP (Structural Classification of Proteins)1NUP    1NUQ    1NUR    1NUS    1NUT    1NUU   
CATH (Classification of proteins structures)1NUP    1NUQ    1NUR    1NUS    1NUT    1NUU   
SuperfamilyQ96T66
Human Protein AtlasENSG00000163864
Peptide AtlasQ96T66
HPRD16370
IPIIPI00290687   IPI00410337   IPI00790045   IPI00964563   IPI00797651   IPI00964842   IPI00793647   IPI00964212   IPI00795380   
Protein Interaction databases
DIP (DOE-UCLA)Q96T66
IntAct (EBI)Q96T66
FunCoupENSG00000163864
BioGRIDNMNAT3
STRING (EMBL)NMNAT3
ZODIACNMNAT3
Ontologies - Pathways
QuickGOQ96T66
Ontology : AmiGOnicotinamide-nucleotide adenylyltransferase activity  nicotinate-nucleotide adenylyltransferase activity  nicotinate-nucleotide adenylyltransferase activity  ATP binding  mitochondrion  mitochondrial matrix  NAD biosynthetic process  response to wounding  NAD metabolic process  'de novo' NAD biosynthetic process from aspartate  
Ontology : EGO-EBInicotinamide-nucleotide adenylyltransferase activity  nicotinate-nucleotide adenylyltransferase activity  nicotinate-nucleotide adenylyltransferase activity  ATP binding  mitochondrion  mitochondrial matrix  NAD biosynthetic process  response to wounding  NAD metabolic process  'de novo' NAD biosynthetic process from aspartate  
Pathways : KEGGNicotinate and nicotinamide metabolism   
NDEx NetworkNMNAT3
Atlas of Cancer Signalling NetworkNMNAT3
Wikipedia pathwaysNMNAT3
Orthology - Evolution
OrthoDB349565
GeneTree (enSembl)ENSG00000163864
Phylogenetic Trees/Animal Genes : TreeFamNMNAT3
HOVERGENQ96T66
HOGENOMQ96T66
Homologs : HomoloGeneNMNAT3
Homology/Alignments : Family Browser (UCSC)NMNAT3
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerNMNAT3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)NMNAT3
dbVarNMNAT3
ClinVarNMNAT3
1000_GenomesNMNAT3 
Exome Variant ServerNMNAT3
ExAC (Exome Aggregation Consortium)NMNAT3 (select the gene name)
Genetic variants : HAPMAP349565
Genomic Variants (DGV)NMNAT3 [DGVbeta]
DECIPHERNMNAT3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisNMNAT3 
Mutations
ICGC Data PortalNMNAT3 
TCGA Data PortalNMNAT3 
Broad Tumor PortalNMNAT3
OASIS PortalNMNAT3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICNMNAT3  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDNMNAT3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch NMNAT3
DgiDB (Drug Gene Interaction Database)NMNAT3
DoCM (Curated mutations)NMNAT3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)NMNAT3 (select a term)
intoGenNMNAT3
Cancer3DNMNAT3(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM608702   
Orphanet
MedgenNMNAT3
Genetic Testing Registry NMNAT3
NextProtQ96T66 [Medical]
TSGene349565
GENETestsNMNAT3
Target ValidationNMNAT3
Huge Navigator NMNAT3 [HugePedia]
snp3D : Map Gene to Disease349565
BioCentury BCIQNMNAT3
ClinGenNMNAT3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD349565
Chemical/Pharm GKB GenePA134952303
Clinical trialNMNAT3
Miscellaneous
canSAR (ICR)NMNAT3 (select the gene name)
Probes
Litterature
PubMed15 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineNMNAT3
EVEXNMNAT3
GoPubMedNMNAT3
iHOPNMNAT3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed May 31 15:32:48 CEST 2017

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