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NMT2 (N-myristoyltransferase 2)

Identity

Other alias-
HGNC (Hugo) NMT2
LocusID (NCBI) 9397
Atlas_Id 45992
Location 10p13  [Link to chromosome band 10p13]
Location_base_pair Starts at 15149865 and ends at 15210709 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
ATP5J2-PTCD1 (7q22.1) / NMT2 (10p13)NMT2 (10p13) / FKBP4 (12p13.33)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)NMT2   7858
Cards
Entrez_Gene (NCBI)NMT2  9397  N-myristoyltransferase 2
Aliases
GeneCards (Weizmann)NMT2
Ensembl hg19 (Hinxton)ENSG00000152465 [Gene_View]  chr10:15149865-15210709 [Contig_View]  NMT2 [Vega]
Ensembl hg38 (Hinxton)ENSG00000152465 [Gene_View]  chr10:15149865-15210709 [Contig_View]  NMT2 [Vega]
ICGC DataPortalENSG00000152465
TCGA cBioPortalNMT2
AceView (NCBI)NMT2
Genatlas (Paris)NMT2
WikiGenes9397
SOURCE (Princeton)NMT2
Genetics Home Reference (NIH)NMT2
Genomic and cartography
GoldenPath hg19 (UCSC)NMT2  -     chr10:15149865-15210709 -  10p13   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)NMT2  -     10p13   [Description]    (hg38-Dec_2013)
EnsemblNMT2 - 10p13 [CytoView hg19]  NMT2 - 10p13 [CytoView hg38]
Mapping of homologs : NCBINMT2 [Mapview hg19]  NMT2 [Mapview hg38]
OMIM603801   
Gene and transcription
Genbank (Entrez)AF043325 AF086423 AK094904 AK123732 AK295277
RefSeq transcript (Entrez)NM_001308295 NM_004808
RefSeq genomic (Entrez)NC_000010 NC_018921 NT_008705 NW_004929370
Consensus coding sequences : CCDS (NCBI)NMT2
Cluster EST : UnigeneHs.60339 [ NCBI ]
CGAP (NCI)Hs.60339
Alternative Splicing GalleryENSG00000152465
Gene ExpressionNMT2 [ NCBI-GEO ]   NMT2 [ EBI - ARRAY_EXPRESS ]   NMT2 [ SEEK ]   NMT2 [ MEM ]
Gene Expression Viewer (FireBrowse)NMT2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)9397
GTEX Portal (Tissue expression)NMT2
Protein : pattern, domain, 3D structure
UniProt/SwissProtO60551   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO60551  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO60551
Splice isoforms : SwissVarO60551
PhosPhoSitePlusO60551
Domaine pattern : Prosite (Expaxy)NMT_1 (PS00975)    NMT_2 (PS00976)   
Domains : Interpro (EBI)Acyl_CoA_acyltransferase    MyristoylCoA_TrFase    MyristoylCoA_TrFase_C    MyristoylCoA_TrFase_CS    MyristoylCoA_TrFase_N   
Domain families : Pfam (Sanger)NMT (PF01233)    NMT_C (PF02799)   
Domain families : Pfam (NCBI)pfam01233    pfam02799   
Conserved Domain (NCBI)NMT2
DMDM Disease mutations9397
Blocks (Seattle)NMT2
PDB (SRS)4C2X   
PDB (PDBSum)4C2X   
PDB (IMB)4C2X   
PDB (RSDB)4C2X   
Structural Biology KnowledgeBase4C2X   
SCOP (Structural Classification of Proteins)4C2X   
CATH (Classification of proteins structures)4C2X   
SuperfamilyO60551
Human Protein AtlasENSG00000152465
Peptide AtlasO60551
HPRD11948
IPIIPI00030223   IPI01015827   IPI00815834   IPI01010722   IPI00477856   IPI00478260   
Protein Interaction databases
DIP (DOE-UCLA)O60551
IntAct (EBI)O60551
FunCoupENSG00000152465
BioGRIDNMT2
STRING (EMBL)NMT2
ZODIACNMT2
Ontologies - Pathways
QuickGOO60551
Ontology : AmiGOglycylpeptide N-tetradecanoyltransferase activity  glycylpeptide N-tetradecanoyltransferase activity  cytoplasm  Golgi apparatus  cytosol  plasma membrane  N-terminal peptidyl-glycine N-myristoylation  extrinsic component of membrane  regulation of rhodopsin mediated signaling pathway  intracellular transport of virus  
Ontology : EGO-EBIglycylpeptide N-tetradecanoyltransferase activity  glycylpeptide N-tetradecanoyltransferase activity  cytoplasm  Golgi apparatus  cytosol  plasma membrane  N-terminal peptidyl-glycine N-myristoylation  extrinsic component of membrane  regulation of rhodopsin mediated signaling pathway  intracellular transport of virus  
NDEx NetworkNMT2
Atlas of Cancer Signalling NetworkNMT2
Wikipedia pathwaysNMT2
Orthology - Evolution
OrthoDB9397
GeneTree (enSembl)ENSG00000152465
Phylogenetic Trees/Animal Genes : TreeFamNMT2
HOVERGENO60551
HOGENOMO60551
Homologs : HomoloGeneNMT2
Homology/Alignments : Family Browser (UCSC)NMT2
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerNMT2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)NMT2
dbVarNMT2
ClinVarNMT2
1000_GenomesNMT2 
Exome Variant ServerNMT2
ExAC (Exome Aggregation Consortium)NMT2 (select the gene name)
Genetic variants : HAPMAP9397
Genomic Variants (DGV)NMT2 [DGVbeta]
DECIPHER (Syndromes)10:15149865-15210709  ENSG00000152465
CONAN: Copy Number AnalysisNMT2 
Mutations
ICGC Data PortalNMT2 
TCGA Data PortalNMT2 
Broad Tumor PortalNMT2
OASIS PortalNMT2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICNMT2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDNMT2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch NMT2
DgiDB (Drug Gene Interaction Database)NMT2
DoCM (Curated mutations)NMT2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)NMT2 (select a term)
intoGenNMT2
Cancer3DNMT2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM603801   
Orphanet
MedgenNMT2
Genetic Testing Registry NMT2
NextProtO60551 [Medical]
TSGene9397
GENETestsNMT2
Huge Navigator NMT2 [HugePedia]
snp3D : Map Gene to Disease9397
BioCentury BCIQNMT2
ClinGenNMT2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD9397
Chemical/Pharm GKB GenePA31662
Clinical trialNMT2
Miscellaneous
canSAR (ICR)NMT2 (select the gene name)
Probes
Litterature
PubMed52 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineNMT2
EVEXNMT2
GoPubMedNMT2
iHOPNMT2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Mar 30 15:12:25 CEST 2017

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