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NMUR1 (neuromedin U receptor 1)

Identity

Alias_namesGPR66
G protein-coupled receptor 66
Alias_symbol (synonym)GPC-R
FM-3
NMU1R
Other alias(FM-3)
FM3
HGNC (Hugo) NMUR1
LocusID (NCBI) 10316
Atlas_Id 70890
Location 2q37.1  [Link to chromosome band 2q37]
Location_base_pair Starts at 231523160 and ends at 231530471 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
NMUR1 (2q37.1) / FZR1 (19p13.3)NMUR1 (2q37.1) / PDE6D (2q37.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)NMUR1   4518
Cards
Entrez_Gene (NCBI)NMUR1  10316  neuromedin U receptor 1
Aliases(FM-3); FM-3; FM3; GPC-R; 
GPR66; NMU1R
GeneCards (Weizmann)NMUR1
Ensembl hg19 (Hinxton)ENSG00000171596 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000171596 [Gene_View]  chr2:231523160-231530471 [Contig_View]  NMUR1 [Vega]
ICGC DataPortalENSG00000171596
TCGA cBioPortalNMUR1
AceView (NCBI)NMUR1
Genatlas (Paris)NMUR1
WikiGenes10316
SOURCE (Princeton)NMUR1
Genetics Home Reference (NIH)NMUR1
Genomic and cartography
GoldenPath hg38 (UCSC)NMUR1  -     chr2:231523160-231530471 -  2q37.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)NMUR1  -     2q37.1   [Description]    (hg19-Feb_2009)
EnsemblNMUR1 - 2q37.1 [CytoView hg19]  NMUR1 - 2q37.1 [CytoView hg38]
Mapping of homologs : NCBINMUR1 [Mapview hg19]  NMUR1 [Mapview hg38]
OMIM604153   
Gene and transcription
Genbank (Entrez)AF272362 AK300222 AK301102 BC036543 BC051914
RefSeq transcript (Entrez)NM_006056
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)NMUR1
Cluster EST : UnigeneHs.471619 [ NCBI ]
CGAP (NCI)Hs.471619
Alternative Splicing GalleryENSG00000171596
Gene ExpressionNMUR1 [ NCBI-GEO ]   NMUR1 [ EBI - ARRAY_EXPRESS ]   NMUR1 [ SEEK ]   NMUR1 [ MEM ]
Gene Expression Viewer (FireBrowse)NMUR1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)10316
GTEX Portal (Tissue expression)NMUR1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9HB89   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9HB89  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9HB89
Splice isoforms : SwissVarQ9HB89
PhosPhoSitePlusQ9HB89
Domaine pattern : Prosite (Expaxy)G_PROTEIN_RECEP_F1_1 (PS00237)    G_PROTEIN_RECEP_F1_2 (PS50262)   
Domains : Interpro (EBI)GPCR_Rhodpsn    GPCR_Rhodpsn_7TM    NeuromedU_rcpt    NeuromedU_rcpt_1   
Domain families : Pfam (Sanger)7tm_1 (PF00001)   
Domain families : Pfam (NCBI)pfam00001   
Domain families : Smart (EMBL)7TM_GPCR_Srsx (SM01381)  
Conserved Domain (NCBI)NMUR1
DMDM Disease mutations10316
Blocks (Seattle)NMUR1
SuperfamilyQ9HB89
Human Protein AtlasENSG00000171596
Peptide AtlasQ9HB89
HPRD16039
IPIIPI00307219   
Protein Interaction databases
DIP (DOE-UCLA)Q9HB89
IntAct (EBI)Q9HB89
FunCoupENSG00000171596
BioGRIDNMUR1
STRING (EMBL)NMUR1
ZODIACNMUR1
Ontologies - Pathways
QuickGOQ9HB89
Ontology : AmiGOneuromedin U receptor activity  G-protein coupled receptor activity  intracellular  plasma membrane  integral component of plasma membrane  calcium ion transport  chloride transport  smooth muscle contraction  G-protein coupled receptor signaling pathway  phospholipase C-activating G-protein coupled receptor signaling pathway  activation of phospholipase C activity  neuropeptide signaling pathway  neuropeptide receptor activity  integral component of membrane  calcium-mediated signaling  inositol phosphate-mediated signaling  positive regulation of protein targeting to mitochondrion  
Ontology : EGO-EBIneuromedin U receptor activity  G-protein coupled receptor activity  intracellular  plasma membrane  integral component of plasma membrane  calcium ion transport  chloride transport  smooth muscle contraction  G-protein coupled receptor signaling pathway  phospholipase C-activating G-protein coupled receptor signaling pathway  activation of phospholipase C activity  neuropeptide signaling pathway  neuropeptide receptor activity  integral component of membrane  calcium-mediated signaling  inositol phosphate-mediated signaling  positive regulation of protein targeting to mitochondrion  
Pathways : KEGGNeuroactive ligand-receptor interaction   
NDEx NetworkNMUR1
Atlas of Cancer Signalling NetworkNMUR1
Wikipedia pathwaysNMUR1
Orthology - Evolution
OrthoDB10316
GeneTree (enSembl)ENSG00000171596
Phylogenetic Trees/Animal Genes : TreeFamNMUR1
HOVERGENQ9HB89
HOGENOMQ9HB89
Homologs : HomoloGeneNMUR1
Homology/Alignments : Family Browser (UCSC)NMUR1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerNMUR1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)NMUR1
dbVarNMUR1
ClinVarNMUR1
1000_GenomesNMUR1 
Exome Variant ServerNMUR1
ExAC (Exome Aggregation Consortium)NMUR1 (select the gene name)
Genetic variants : HAPMAP10316
Genomic Variants (DGV)NMUR1 [DGVbeta]
DECIPHERNMUR1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisNMUR1 
Mutations
ICGC Data PortalNMUR1 
TCGA Data PortalNMUR1 
Broad Tumor PortalNMUR1
OASIS PortalNMUR1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICNMUR1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDNMUR1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch NMUR1
DgiDB (Drug Gene Interaction Database)NMUR1
DoCM (Curated mutations)NMUR1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)NMUR1 (select a term)
intoGenNMUR1
Cancer3DNMUR1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM604153   
Orphanet
MedgenNMUR1
Genetic Testing Registry NMUR1
NextProtQ9HB89 [Medical]
TSGene10316
GENETestsNMUR1
Target ValidationNMUR1
Huge Navigator NMUR1 [HugePedia]
snp3D : Map Gene to Disease10316
BioCentury BCIQNMUR1
ClinGenNMUR1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD10316
Chemical/Pharm GKB GenePA28910
Clinical trialNMUR1
Miscellaneous
canSAR (ICR)NMUR1 (select the gene name)
Probes
Litterature
PubMed13 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineNMUR1
EVEXNMUR1
GoPubMedNMUR1
iHOPNMUR1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 18 13:32:08 CEST 2017

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