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NMUR2 (neuromedin U receptor 2)

Identity

Alias (NCBI)FM-4
FM4
NMU-R2
NMU2R
TGR-1
TGR1
HGNC (Hugo) NMUR2
HGNC Previous nameNMU2R
LocusID (NCBI) 56923
Atlas_Id 55799
Location 5q33.1  [Link to chromosome band 5q33]
Location_base_pair Starts at 152391546 and ends at 152405279 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)NMUR2   16454
Cards
Entrez_Gene (NCBI)NMUR2    neuromedin U receptor 2
AliasesFM-4; FM4; NMU-R2; NMU2R; 
TGR-1; TGR1
GeneCards (Weizmann)NMUR2
Ensembl hg19 (Hinxton)ENSG00000132911 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000132911 [Gene_View]  ENSG00000132911 [Sequence]  chr5:152391546-152405279 [Contig_View]  NMUR2 [Vega]
ICGC DataPortalENSG00000132911
TCGA cBioPortalNMUR2
AceView (NCBI)NMUR2
Genatlas (Paris)NMUR2
SOURCE (Princeton)NMUR2
Genetics Home Reference (NIH)NMUR2
Genomic and cartography
GoldenPath hg38 (UCSC)NMUR2  -     chr5:152391546-152405279 -  5q33.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)NMUR2  -     5q33.1   [Description]    (hg19-Feb_2009)
GoldenPathNMUR2 - 5q33.1 [CytoView hg19]  NMUR2 - 5q33.1 [CytoView hg38]
ImmunoBaseENSG00000132911
Genome Data Viewer NCBINMUR2 [Mapview hg19]  
OMIM605108   
Gene and transcription
Genbank (Entrez)AB041228 AF242874 AF272363 AF292402 AI023570
RefSeq transcript (Entrez)NM_020167
Consensus coding sequences : CCDS (NCBI)NMUR2
Gene ExpressionNMUR2 [ NCBI-GEO ]   NMUR2 [ EBI - ARRAY_EXPRESS ]   NMUR2 [ SEEK ]   NMUR2 [ MEM ]
Gene Expression Viewer (FireBrowse)NMUR2 [ Firebrowse - Broad ]
GenevisibleExpression of NMUR2 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)56923
GTEX Portal (Tissue expression)NMUR2
Human Protein AtlasENSG00000132911-NMUR2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9GZQ4   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9GZQ4  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9GZQ4
PhosPhoSitePlusQ9GZQ4
Domaine pattern : Prosite (Expaxy)G_PROTEIN_RECEP_F1_1 (PS00237)    G_PROTEIN_RECEP_F1_2 (PS50262)   
Domains : Interpro (EBI)GPCR_Rhodpsn    GPCR_Rhodpsn_7TM    NeuromedU_rcpt    NeuromedU_rcpt_2   
Domain families : Pfam (Sanger)7tm_1 (PF00001)   
Domain families : Pfam (NCBI)pfam00001   
Domain families : Smart (EMBL)7TM_GPCR_Srsx (SM01381)  
Conserved Domain (NCBI)NMUR2
SuperfamilyQ9GZQ4
AlphaFold pdb e-kbQ9GZQ4   
Human Protein Atlas [tissue]ENSG00000132911-NMUR2 [tissue]
HPRD12003
Protein Interaction databases
DIP (DOE-UCLA)Q9GZQ4
IntAct (EBI)Q9GZQ4
BioGRIDNMUR2
STRING (EMBL)NMUR2
ZODIACNMUR2
Ontologies - Pathways
QuickGOQ9GZQ4
Ontology : AmiGOneuromedin U receptor activity  reduction of food intake in response to dietary excess  G protein-coupled receptor activity  intracellular calcium activated chloride channel activity  protein binding  GTP binding  plasma membrane  plasma membrane  calcium ion transport  regulation of smooth muscle contraction  G protein-coupled receptor signaling pathway  phospholipase C-activating G protein-coupled receptor signaling pathway  positive regulation of cytosolic calcium ion concentration  neuropeptide signaling pathway  cell-cell signaling  central nervous system development  grooming behavior  feeding behavior  inorganic anion transport  integral component of membrane  calcium-mediated signaling  neuromedin U binding  activation of phospholipase A2 activity by calcium-mediated signaling  inositol phosphate-mediated signaling  response to pain  arachidonic acid secretion  regulation of sensory perception of pain  
Ontology : EGO-EBIneuromedin U receptor activity  reduction of food intake in response to dietary excess  G protein-coupled receptor activity  intracellular calcium activated chloride channel activity  protein binding  GTP binding  plasma membrane  plasma membrane  calcium ion transport  regulation of smooth muscle contraction  G protein-coupled receptor signaling pathway  phospholipase C-activating G protein-coupled receptor signaling pathway  positive regulation of cytosolic calcium ion concentration  neuropeptide signaling pathway  cell-cell signaling  central nervous system development  grooming behavior  feeding behavior  inorganic anion transport  integral component of membrane  calcium-mediated signaling  neuromedin U binding  activation of phospholipase A2 activity by calcium-mediated signaling  inositol phosphate-mediated signaling  response to pain  arachidonic acid secretion  regulation of sensory perception of pain  
Pathways : KEGGNeuroactive ligand-receptor interaction   
NDEx NetworkNMUR2
Atlas of Cancer Signalling NetworkNMUR2
Wikipedia pathwaysNMUR2
Orthology - Evolution
OrthoDB56923
GeneTree (enSembl)ENSG00000132911
Phylogenetic Trees/Animal Genes : TreeFamNMUR2
Homologs : HomoloGeneNMUR2
Homology/Alignments : Family Browser (UCSC)NMUR2
Gene fusions - Rearrangements
Fusion : QuiverNMUR2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerNMUR2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)NMUR2
dbVarNMUR2
ClinVarNMUR2
MonarchNMUR2
1000_GenomesNMUR2 
Exome Variant ServerNMUR2
GNOMAD BrowserENSG00000132911
Varsome BrowserNMUR2
ACMGNMUR2 variants
VarityQ9GZQ4
Genomic Variants (DGV)NMUR2 [DGVbeta]
DECIPHERNMUR2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisNMUR2 
Mutations
ICGC Data PortalNMUR2 
TCGA Data PortalNMUR2 
Broad Tumor PortalNMUR2
OASIS PortalNMUR2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICNMUR2  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DNMUR2
Mutations and Diseases : HGMDNMUR2
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaNMUR2
DgiDB (Drug Gene Interaction Database)NMUR2
DoCM (Curated mutations)NMUR2
CIViC (Clinical Interpretations of Variants in Cancer)NMUR2
Cancer3DNMUR2
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM605108   
Orphanet
DisGeNETNMUR2
MedgenNMUR2
Genetic Testing Registry NMUR2
NextProtQ9GZQ4 [Medical]
GENETestsNMUR2
Target ValidationNMUR2
Huge Navigator NMUR2 [HugePedia]
ClinGenNMUR2
Clinical trials, drugs, therapy
MyCancerGenomeNMUR2
Protein Interactions : CTDNMUR2
Pharm GKB GenePA31664
PharosQ9GZQ4
Clinical trialNMUR2
Miscellaneous
canSAR (ICR)NMUR2
HarmonizomeNMUR2
DataMed IndexNMUR2
Probes
Litterature
PubMed20 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXNMUR2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:22:58 CEST 2021

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