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NMUR2 (neuromedin U receptor 2)

Identity

Alias_namesNMU2R
Other aliasFM-4
FM4
NMU-R2
TGR-1
TGR1
HGNC (Hugo) NMUR2
LocusID (NCBI) 56923
Atlas_Id 55799
Location 5q33.1  [Link to chromosome band 5q33]
Location_base_pair Starts at 152391541 and ends at 152405279 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)NMUR2   16454
Cards
Entrez_Gene (NCBI)NMUR2  56923  neuromedin U receptor 2
AliasesFM-4; FM4; NMU-R2; NMU2R; 
TGR-1; TGR1
GeneCards (Weizmann)NMUR2
Ensembl hg19 (Hinxton)ENSG00000132911 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000132911 [Gene_View]  chr5:152391541-152405279 [Contig_View]  NMUR2 [Vega]
ICGC DataPortalENSG00000132911
TCGA cBioPortalNMUR2
AceView (NCBI)NMUR2
Genatlas (Paris)NMUR2
WikiGenes56923
SOURCE (Princeton)NMUR2
Genetics Home Reference (NIH)NMUR2
Genomic and cartography
GoldenPath hg38 (UCSC)NMUR2  -     chr5:152391541-152405279 -  5q33.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)NMUR2  -     5q33.1   [Description]    (hg19-Feb_2009)
EnsemblNMUR2 - 5q33.1 [CytoView hg19]  NMUR2 - 5q33.1 [CytoView hg38]
Mapping of homologs : NCBINMUR2 [Mapview hg19]  NMUR2 [Mapview hg38]
OMIM605108   
Gene and transcription
Genbank (Entrez)AB041228 AF242874 AF272363 AF292402 AI023570
RefSeq transcript (Entrez)NM_020167
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)NMUR2
Cluster EST : UnigeneHs.731911 [ NCBI ]
CGAP (NCI)Hs.731911
Alternative Splicing GalleryENSG00000132911
Gene ExpressionNMUR2 [ NCBI-GEO ]   NMUR2 [ EBI - ARRAY_EXPRESS ]   NMUR2 [ SEEK ]   NMUR2 [ MEM ]
Gene Expression Viewer (FireBrowse)NMUR2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)56923
GTEX Portal (Tissue expression)NMUR2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9GZQ4   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9GZQ4  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9GZQ4
Splice isoforms : SwissVarQ9GZQ4
PhosPhoSitePlusQ9GZQ4
Domaine pattern : Prosite (Expaxy)G_PROTEIN_RECEP_F1_1 (PS00237)    G_PROTEIN_RECEP_F1_2 (PS50262)   
Domains : Interpro (EBI)GPCR_Rhodpsn    GPCR_Rhodpsn_7TM    NeuromedU_rcpt    NeuromedU_rcpt_2   
Domain families : Pfam (Sanger)7tm_1 (PF00001)   
Domain families : Pfam (NCBI)pfam00001   
Domain families : Smart (EMBL)7TM_GPCR_Srsx (SM01381)  
Conserved Domain (NCBI)NMUR2
DMDM Disease mutations56923
Blocks (Seattle)NMUR2
SuperfamilyQ9GZQ4
Human Protein AtlasENSG00000132911
Peptide AtlasQ9GZQ4
HPRD12003
IPIIPI00100753   
Protein Interaction databases
DIP (DOE-UCLA)Q9GZQ4
IntAct (EBI)Q9GZQ4
FunCoupENSG00000132911
BioGRIDNMUR2
STRING (EMBL)NMUR2
ZODIACNMUR2
Ontologies - Pathways
QuickGOQ9GZQ4
Ontology : AmiGOneuromedin U receptor activity  reduction of food intake in response to dietary excess  G-protein coupled receptor activity  intracellular calcium activated chloride channel activity  protein binding  GTP binding  intracellular  plasma membrane  calcium ion transport  regulation of smooth muscle contraction  phospholipase C-activating G-protein coupled receptor signaling pathway  positive regulation of cytosolic calcium ion concentration  neuropeptide signaling pathway  cell-cell signaling  central nervous system development  grooming behavior  feeding behavior  integral component of membrane  calcium-mediated signaling  neuromedin U binding  activation of phospholipase A2 activity by calcium-mediated signaling  inositol phosphate-mediated signaling  response to pain  arachidonic acid secretion  chloride transmembrane transport  
Ontology : EGO-EBIneuromedin U receptor activity  reduction of food intake in response to dietary excess  G-protein coupled receptor activity  intracellular calcium activated chloride channel activity  protein binding  GTP binding  intracellular  plasma membrane  calcium ion transport  regulation of smooth muscle contraction  phospholipase C-activating G-protein coupled receptor signaling pathway  positive regulation of cytosolic calcium ion concentration  neuropeptide signaling pathway  cell-cell signaling  central nervous system development  grooming behavior  feeding behavior  integral component of membrane  calcium-mediated signaling  neuromedin U binding  activation of phospholipase A2 activity by calcium-mediated signaling  inositol phosphate-mediated signaling  response to pain  arachidonic acid secretion  chloride transmembrane transport  
Pathways : KEGGNeuroactive ligand-receptor interaction   
NDEx NetworkNMUR2
Atlas of Cancer Signalling NetworkNMUR2
Wikipedia pathwaysNMUR2
Orthology - Evolution
OrthoDB56923
GeneTree (enSembl)ENSG00000132911
Phylogenetic Trees/Animal Genes : TreeFamNMUR2
HOVERGENQ9GZQ4
HOGENOMQ9GZQ4
Homologs : HomoloGeneNMUR2
Homology/Alignments : Family Browser (UCSC)NMUR2
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerNMUR2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)NMUR2
dbVarNMUR2
ClinVarNMUR2
1000_GenomesNMUR2 
Exome Variant ServerNMUR2
ExAC (Exome Aggregation Consortium)NMUR2 (select the gene name)
Genetic variants : HAPMAP56923
Genomic Variants (DGV)NMUR2 [DGVbeta]
DECIPHERNMUR2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisNMUR2 
Mutations
ICGC Data PortalNMUR2 
TCGA Data PortalNMUR2 
Broad Tumor PortalNMUR2
OASIS PortalNMUR2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICNMUR2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDNMUR2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch NMUR2
DgiDB (Drug Gene Interaction Database)NMUR2
DoCM (Curated mutations)NMUR2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)NMUR2 (select a term)
intoGenNMUR2
Cancer3DNMUR2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM605108   
Orphanet
MedgenNMUR2
Genetic Testing Registry NMUR2
NextProtQ9GZQ4 [Medical]
TSGene56923
GENETestsNMUR2
Target ValidationNMUR2
Huge Navigator NMUR2 [HugePedia]
snp3D : Map Gene to Disease56923
BioCentury BCIQNMUR2
ClinGenNMUR2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD56923
Chemical/Pharm GKB GenePA31664
Clinical trialNMUR2
Miscellaneous
canSAR (ICR)NMUR2 (select the gene name)
Probes
Litterature
PubMed17 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineNMUR2
EVEXNMUR2
GoPubMedNMUR2
iHOPNMUR2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Jun 7 12:47:03 CEST 2017

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