Atlas of Genetics and Cytogenetics in Oncology and Haematology


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NOC2L (NOC2 like nucleolar associated transcriptional repressor)

Identity

Other namesNET15
NET7
NIR
PPP1R112
HGNC (Hugo) NOC2L
LocusID (NCBI) 26155
Atlas_Id 40316
Location 1p36.33  [Link to chromosome band 1p36]
Location_base_pair Starts at 879583 and ends at 894679 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
RPL35 (9q33.3) / NOC2L (1p36.33)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)NOC2L   24517
Cards
Entrez_Gene (NCBI)NOC2L  26155  NOC2 like nucleolar associated transcriptional repressor
AliasesNET15; NET7; NIR; PPP1R112
GeneCards (Weizmann)NOC2L
Ensembl hg19 (Hinxton)ENSG00000188976 [Gene_View]  chr1:879583-894679 [Contig_View]  NOC2L [Vega]
Ensembl hg38 (Hinxton)ENSG00000188976 [Gene_View]  chr1:879583-894679 [Contig_View]  NOC2L [Vega]
ICGC DataPortalENSG00000188976
TCGA cBioPortalNOC2L
AceView (NCBI)NOC2L
Genatlas (Paris)NOC2L
WikiGenes26155
SOURCE (Princeton)NOC2L
Genomic and cartography
GoldenPath hg19 (UCSC)NOC2L  -     chr1:879583-894679 -  1p36.33   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)NOC2L  -     1p36.33   [Description]    (hg38-Dec_2013)
EnsemblNOC2L - 1p36.33 [CytoView hg19]  NOC2L - 1p36.33 [CytoView hg38]
Mapping of homologs : NCBINOC2L [Mapview hg19]  NOC2L [Mapview hg38]
OMIM610770   
Gene and transcription
Genbank (Entrez)AK022756 AK024284 AK092491 AK225239 AK315080
RefSeq transcript (Entrez)NM_015658
RefSeq genomic (Entrez)NC_000001 NC_018912 NT_032977 NW_004929288
Consensus coding sequences : CCDS (NCBI)NOC2L
Cluster EST : UnigeneHs.405987 [ NCBI ]
CGAP (NCI)Hs.405987
Alternative Splicing GalleryENSG00000188976
Gene ExpressionNOC2L [ NCBI-GEO ]   NOC2L [ EBI - ARRAY_EXPRESS ]   NOC2L [ SEEK ]   NOC2L [ MEM ]
Gene Expression Viewer (FireBrowse)NOC2L [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)26155
GTEX Portal (Tissue expression)NOC2L
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9Y3T9 (Uniprot)
NextProtQ9Y3T9  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9Y3T9
Splice isoforms : SwissVarQ9Y3T9 (Swissvar)
PhosPhoSitePlusQ9Y3T9
Domains : Interpro (EBI)ARM-type_fold    Noc2   
Domain families : Pfam (Sanger)Noc2 (PF03715)   
Domain families : Pfam (NCBI)pfam03715   
DMDM Disease mutations26155
Blocks (Seattle)NOC2L
SuperfamilyQ9Y3T9
Human Protein AtlasENSG00000188976
Peptide AtlasQ9Y3T9
HPRD13166
IPIIPI00411886   IPI00921079   IPI00385785   
Protein Interaction databases
DIP (DOE-UCLA)Q9Y3T9
IntAct (EBI)Q9Y3T9
FunCoupENSG00000188976
BioGRIDNOC2L
STRING (EMBL)NOC2L
ZODIACNOC2L
Ontologies - Pathways
QuickGOQ9Y3T9
Ontology : AmiGOnegative regulation of transcription from RNA polymerase II promoter  negative regulation of B cell apoptotic process  chromatin binding  transcription corepressor activity  protein binding  nucleus  nucleoplasm  nucleoplasm  nucleolus  cytoplasm  transcription, DNA-templated  apoptotic process  Noc1p-Noc2p complex  Noc2p-Noc3p complex  nucleosome binding  chromatin assembly  nucleolus to nucleoplasm transport  cellular response to UV  negative regulation of histone acetylation  ribosomal large subunit biogenesis  histone binding  poly(A) RNA binding  repressing transcription factor binding  regulation of signal transduction by p53 class mediator  negative regulation of intrinsic apoptotic signaling pathway  
Ontology : EGO-EBInegative regulation of transcription from RNA polymerase II promoter  negative regulation of B cell apoptotic process  chromatin binding  transcription corepressor activity  protein binding  nucleus  nucleoplasm  nucleoplasm  nucleolus  cytoplasm  transcription, DNA-templated  apoptotic process  Noc1p-Noc2p complex  Noc2p-Noc3p complex  nucleosome binding  chromatin assembly  nucleolus to nucleoplasm transport  cellular response to UV  negative regulation of histone acetylation  ribosomal large subunit biogenesis  histone binding  poly(A) RNA binding  repressing transcription factor binding  regulation of signal transduction by p53 class mediator  negative regulation of intrinsic apoptotic signaling pathway  
NDEx Network
Atlas of Cancer Signalling NetworkNOC2L
Wikipedia pathwaysNOC2L
Orthology - Evolution
OrthoDB26155
GeneTree (enSembl)ENSG00000188976
Phylogenetic Trees/Animal Genes : TreeFamNOC2L
Homologs : HomoloGeneNOC2L
Homology/Alignments : Family Browser (UCSC)NOC2L
Gene fusions - Rearrangements
Polymorphisms : SNP, variants
NCBI Variation ViewerNOC2L [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)NOC2L
dbVarNOC2L
ClinVarNOC2L
1000_GenomesNOC2L 
Exome Variant ServerNOC2L
ExAC (Exome Aggregation Consortium)NOC2L (select the gene name)
Genetic variants : HAPMAP26155
Genomic Variants (DGV)NOC2L [DGVbeta]
Mutations
ICGC Data PortalNOC2L 
TCGA Data PortalNOC2L 
Broad Tumor PortalNOC2L
OASIS PortalNOC2L [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICNOC2L 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch NOC2L
DgiDB (Drug Gene Interaction Database)NOC2L
DoCM (Curated mutations)NOC2L (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)NOC2L (select a term)
intoGenNOC2L
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)1:879583-894679  ENSG00000188976
CONAN: Copy Number AnalysisNOC2L 
Mutations and Diseases : HGMDNOC2L
OMIM610770   
MedgenNOC2L
Genetic Testing Registry NOC2L
NextProtQ9Y3T9 [Medical]
TSGene26155
GENETestsNOC2L
Huge Navigator NOC2L [HugePedia]
snp3D : Map Gene to Disease26155
BioCentury BCIQNOC2L
ClinGenNOC2L
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD26155
Chemical/Pharm GKB GenePA142671261
Clinical trialNOC2L
Miscellaneous
canSAR (ICR)NOC2L (select the gene name)
Probes
Litterature
PubMed42 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineNOC2L
EVEXNOC2L
GoPubMedNOC2L
iHOPNOC2L
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Aug 9 19:19:57 CEST 2016

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