Atlas of Genetics and Cytogenetics in Oncology and Haematology


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NOG (noggin)

Identity

Other namesSYM1
SYNS1
HGNC (Hugo) NOG
LocusID (NCBI) 9241
Location 17q22
Location_base_pair Starts at 54671060 and ends at 54672951 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)NOG   7866
Cards
Entrez_Gene (NCBI)NOG  9241  noggin
GeneCards (Weizmann)NOG
Ensembl (Hinxton)ENSG00000183691 [Gene_View]  chr17:54671060-54672951 [Contig_View]  NOG [Vega]
ICGC DataPortalENSG00000183691
cBioPortalNOG
AceView (NCBI)NOG
Genatlas (Paris)NOG
WikiGenes9241
SOURCE (Princeton)NM_005450
Genomic and cartography
GoldenPath (UCSC)NOG  -  17q22   chr17:54671060-54672951 +  17q22   [Description]    (hg19-Feb_2009)
EnsemblNOG - 17q22 [CytoView]
Mapping of homologs : NCBINOG [Mapview]
OMIM184460   185800   186500   186570   602991   611377   
Gene and transcription
Genbank (Entrez)AK314080 BC034027
RefSeq transcript (Entrez)NM_005450
RefSeq genomic (Entrez)AC_000149 NC_000017 NC_018928 NG_011958 NT_010783 NW_001838448 NW_004929407
Consensus coding sequences : CCDS (NCBI)NOG
Cluster EST : UnigeneHs.248201 [ NCBI ]
CGAP (NCI)Hs.248201
Alternative Splicing : Fast-db (Paris)GSHG0012663
Alternative Splicing GalleryENSG00000183691
Gene ExpressionNOG [ NCBI-GEO ]     NOG [ SEEK ]   NOG [ MEM ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ13253 (Uniprot)
NextProtQ13253  [Medical]
With graphics : InterProQ13253
Splice isoforms : SwissVarQ13253 (Swissvar)
Domains : Interpro (EBI)Cystine-knot_cytokine [organisation]   Noggin [organisation]  
Related proteins : CluSTrQ13253
Domain families : Pfam (Sanger)Noggin (PF05806)   
Domain families : Pfam (NCBI)pfam05806   
DMDM Disease mutations9241
Blocks (Seattle)Q13253
PDB (SRS)1M4U   
PDB (PDBSum)1M4U   
PDB (IMB)1M4U   
PDB (RSDB)1M4U   
Human Protein AtlasENSG00000183691 [gene] [tissue] [antibody] [cell] [cancer]
Peptide AtlasQ13253
HPRD04291
IPIIPI00012361   
Protein Interaction databases
DIP (DOE-UCLA)Q13253
IntAct (EBI)Q13253
FunCoupENSG00000183691
BioGRIDNOG
InParanoidQ13253
Interologous Interaction database Q13253
IntegromeDBNOG
STRING (EMBL)NOG
Ontologies - Pathways
Ontology : AmiGOnegative regulation of transcription from RNA polymerase II promoter  skeletal system development  osteoblast differentiation  in utero embryonic development  endoderm formation  mesoderm formation  epithelial to mesenchymal transition  neural plate morphogenesis  neural tube closure  protein binding  extracellular region  extracellular space  nervous system development  motor neuron axon guidance  dorsal/ventral pattern formation  cytokine binding  spinal cord development  cell differentiation in hindbrain  pituitary gland development  negative regulation of cell migration  BMP signaling pathway  negative regulation of BMP signaling pathway  negative regulation of BMP signaling pathway  somatic stem cell maintenance  wound healing  middle ear morphogenesis  embryonic digit morphogenesis  protein homodimerization activity  negative regulation of osteoblast differentiation  positive regulation of transcription from RNA polymerase II promoter  axial mesoderm development  notochord morphogenesis  embryonic skeletal system development  negative regulation of astrocyte differentiation  positive regulation of epithelial cell proliferation  cartilage development  negative regulation of cardiac muscle cell proliferation  limb development  embryonic skeletal joint morphogenesis  negative regulation of cytokine activity  face morphogenesis  negative regulation of pathway-restricted SMAD protein phosphorylation  lung morphogenesis  prostatic bud formation  ureteric bud formation  fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation  negative regulation of cartilage development  somite development  cellular response to BMP stimulus  negative regulation of canonical Wnt signaling pathway  positive regulation of branching involved in ureteric bud morphogenesis  positive regulation of glomerulus development  regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation  negative regulation of apoptotic signaling pathway  
Ontology : EGO-EBInegative regulation of transcription from RNA polymerase II promoter  skeletal system development  osteoblast differentiation  in utero embryonic development  endoderm formation  mesoderm formation  epithelial to mesenchymal transition  neural plate morphogenesis  neural tube closure  protein binding  extracellular region  extracellular space  nervous system development  motor neuron axon guidance  dorsal/ventral pattern formation  cytokine binding  spinal cord development  cell differentiation in hindbrain  pituitary gland development  negative regulation of cell migration  BMP signaling pathway  negative regulation of BMP signaling pathway  negative regulation of BMP signaling pathway  somatic stem cell maintenance  wound healing  middle ear morphogenesis  embryonic digit morphogenesis  protein homodimerization activity  negative regulation of osteoblast differentiation  positive regulation of transcription from RNA polymerase II promoter  axial mesoderm development  notochord morphogenesis  embryonic skeletal system development  negative regulation of astrocyte differentiation  positive regulation of epithelial cell proliferation  cartilage development  negative regulation of cardiac muscle cell proliferation  limb development  embryonic skeletal joint morphogenesis  negative regulation of cytokine activity  face morphogenesis  negative regulation of pathway-restricted SMAD protein phosphorylation  lung morphogenesis  prostatic bud formation  ureteric bud formation  fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation  negative regulation of cartilage development  somite development  cellular response to BMP stimulus  negative regulation of canonical Wnt signaling pathway  positive regulation of branching involved in ureteric bud morphogenesis  positive regulation of glomerulus development  regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation  negative regulation of apoptotic signaling pathway  
Pathways : BIOCARTAALK in cardiac myocytes [Genes]   
Pathways : KEGGTGF-beta signaling pathway   
Protein Interaction DatabaseNOG
Wikipedia pathwaysNOG
Gene fusion - rearrangments
Polymorphisms : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)NOG
snp3D : Map Gene to Disease9241
SNP (GeneSNP Utah)NOG
SNP : HGBaseNOG
Genetic variants : HAPMAPNOG
Exome VariantNOG
1000_GenomesNOG 
ICGC programENSG00000183691 
Somatic Mutations in Cancer : COSMICNOG 
CONAN: Copy Number AnalysisNOG 
Mutations and Diseases : HGMDNOG
Genomic VariantsNOG  NOG [DGVbeta]
dbVarNOG
ClinVarNOG
Pred. of missensesPolyPhen-2  SIFT(SG)  SIFT(JCVI)  Align-GVGD  MutAssessor  Mutanalyser  
Pred. splicesGeneSplicer  Human Splicing Finder  MaxEntScan  
Diseases
OMIM184460    185800    186500    186570    602991    611377   
MedgenNOG
GENETestsNOG
Disease Genetic AssociationNOG
Huge Navigator NOG [HugePedia]  NOG [HugeCancerGEM]
General knowledge
Homologs : HomoloGeneNOG
Homology/Alignments : Family Browser (UCSC)NOG
Phylogenetic Trees/Animal Genes : TreeFamNOG
Chemical/Protein Interactions : CTD9241
Chemical/Pharm GKB GenePA31670
Clinical trialNOG
Cancer Resource (Charite)ENSG00000183691
Other databases
Probes
Litterature
PubMed78 Pubmed reference(s) in Entrez
CoreMineNOG
iHOPNOG
OncoSearchNOG
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Jul 30 14:07:45 CEST 2014

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