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NOG (noggin)

Identity

Other namesSYM1
SYNS1
SYNS1A
HGNC (Hugo) NOG
LocusID (NCBI) 9241
Atlas_Id 41551
Location 17q22
Location_base_pair Starts at 54671060 and ends at 54672951 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)NOG   7866
Cards
Entrez_Gene (NCBI)NOG  9241  noggin
AliasesSYM1; SYNS1; SYNS1A
GeneCards (Weizmann)NOG
Ensembl hg19 (Hinxton)ENSG00000183691 [Gene_View]  chr17:54671060-54672951 [Contig_View]  NOG [Vega]
Ensembl hg38 (Hinxton)ENSG00000183691 [Gene_View]  chr17:54671060-54672951 [Contig_View]  NOG [Vega]
ICGC DataPortalENSG00000183691
TCGA cBioPortalNOG
AceView (NCBI)NOG
Genatlas (Paris)NOG
WikiGenes9241
SOURCE (Princeton)NOG
Genomic and cartography
GoldenPath hg19 (UCSC)NOG  -     chr17:54671060-54672951 +  17q22   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)NOG  -     17q22   [Description]    (hg38-Dec_2013)
EnsemblNOG - 17q22 [CytoView hg19]  NOG - 17q22 [CytoView hg38]
Mapping of homologs : NCBINOG [Mapview hg19]  NOG [Mapview hg38]
OMIM184460   185800   186500   186570   602991   611377   
Gene and transcription
Genbank (Entrez)AK314080 BC034027
RefSeq transcript (Entrez)NM_005450
RefSeq genomic (Entrez)NC_000017 NC_018928 NG_011958 NT_010783 NW_004929407
Consensus coding sequences : CCDS (NCBI)NOG
Cluster EST : UnigeneHs.248201 [ NCBI ]
CGAP (NCI)Hs.248201
Alternative Splicing GalleryENSG00000183691
Gene ExpressionNOG [ NCBI-GEO ]   NOG [ EBI - ARRAY_EXPRESS ]   NOG [ SEEK ]   NOG [ MEM ]
Gene Expression Viewer (FireBrowse)NOG [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)9241
GTEX Portal (Tissue expression)NOG
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ13253 (Uniprot)
NextProtQ13253  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ13253
Splice isoforms : SwissVarQ13253 (Swissvar)
PhosPhoSitePlusQ13253
Domains : Interpro (EBI)Cystine-knot_cytokine    Noggin   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
DMDM Disease mutations9241
Blocks (Seattle)NOG
PDB (SRS)1M4U   
PDB (PDBSum)1M4U   
PDB (IMB)1M4U   
PDB (RSDB)1M4U   
Structural Biology KnowledgeBase1M4U   
SCOP (Structural Classification of Proteins)1M4U   
CATH (Classification of proteins structures)1M4U   
SuperfamilyQ13253
Human Protein AtlasENSG00000183691
Peptide AtlasQ13253
HPRD04291
IPIIPI00012361   
Protein Interaction databases
DIP (DOE-UCLA)Q13253
IntAct (EBI)Q13253
FunCoupENSG00000183691
BioGRIDNOG
STRING (EMBL)NOG
ZODIACNOG
Ontologies - Pathways
QuickGOQ13253
Ontology : AmiGOnegative regulation of transcription from RNA polymerase II promoter  skeletal system development  osteoblast differentiation  in utero embryonic development  endoderm formation  mesoderm formation  epithelial to mesenchymal transition  neural plate morphogenesis  neural tube closure  protein binding  extracellular region  extracellular space  nervous system development  motor neuron axon guidance  dorsal/ventral pattern formation  cytokine binding  spinal cord development  cell differentiation in hindbrain  pituitary gland development  negative regulation of cell migration  BMP signaling pathway  negative regulation of BMP signaling pathway  negative regulation of BMP signaling pathway  protein complex binding  somatic stem cell population maintenance  wound healing  middle ear morphogenesis  embryonic digit morphogenesis  protein homodimerization activity  regulation of neuron differentiation  negative regulation of osteoblast differentiation  positive regulation of transcription from RNA polymerase II promoter  axial mesoderm development  notochord morphogenesis  embryonic skeletal system development  negative regulation of astrocyte differentiation  positive regulation of epithelial cell proliferation  cartilage development  negative regulation of cardiac muscle cell proliferation  limb development  embryonic skeletal joint morphogenesis  negative regulation of cytokine activity  face morphogenesis  negative regulation of pathway-restricted SMAD protein phosphorylation  lung morphogenesis  prostatic bud formation  ureteric bud formation  fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation  negative regulation of cartilage development  somite development  negative regulation of canonical Wnt signaling pathway  positive regulation of branching involved in ureteric bud morphogenesis  positive regulation of glomerulus development  regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation  negative regulation of apoptotic signaling pathway  
Ontology : EGO-EBInegative regulation of transcription from RNA polymerase II promoter  skeletal system development  osteoblast differentiation  in utero embryonic development  endoderm formation  mesoderm formation  epithelial to mesenchymal transition  neural plate morphogenesis  neural tube closure  protein binding  extracellular region  extracellular space  nervous system development  motor neuron axon guidance  dorsal/ventral pattern formation  cytokine binding  spinal cord development  cell differentiation in hindbrain  pituitary gland development  negative regulation of cell migration  BMP signaling pathway  negative regulation of BMP signaling pathway  negative regulation of BMP signaling pathway  protein complex binding  somatic stem cell population maintenance  wound healing  middle ear morphogenesis  embryonic digit morphogenesis  protein homodimerization activity  regulation of neuron differentiation  negative regulation of osteoblast differentiation  positive regulation of transcription from RNA polymerase II promoter  axial mesoderm development  notochord morphogenesis  embryonic skeletal system development  negative regulation of astrocyte differentiation  positive regulation of epithelial cell proliferation  cartilage development  negative regulation of cardiac muscle cell proliferation  limb development  embryonic skeletal joint morphogenesis  negative regulation of cytokine activity  face morphogenesis  negative regulation of pathway-restricted SMAD protein phosphorylation  lung morphogenesis  prostatic bud formation  ureteric bud formation  fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation  negative regulation of cartilage development  somite development  negative regulation of canonical Wnt signaling pathway  positive regulation of branching involved in ureteric bud morphogenesis  positive regulation of glomerulus development  regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation  negative regulation of apoptotic signaling pathway  
Pathways : BIOCARTAALK in cardiac myocytes [Genes]   
Pathways : KEGGTGF-beta signaling pathway   
NDEx Network
Atlas of Cancer Signalling NetworkNOG
Wikipedia pathwaysNOG
Orthology - Evolution
OrthoDB9241
GeneTree (enSembl)ENSG00000183691
Phylogenetic Trees/Animal Genes : TreeFamNOG
Homologs : HomoloGeneNOG
Homology/Alignments : Family Browser (UCSC)NOG
Gene fusions - Rearrangements
Polymorphisms : SNP, variants
NCBI Variation ViewerNOG [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)NOG
dbVarNOG
ClinVarNOG
1000_GenomesNOG 
Exome Variant ServerNOG
ExAC (Exome Aggregation Consortium)NOG (select the gene name)
Genetic variants : HAPMAP9241
Genomic Variants (DGV)NOG [DGVbeta]
Mutations
ICGC Data PortalNOG 
TCGA Data PortalNOG 
Broad Tumor PortalNOG
OASIS PortalNOG [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICNOG 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)Mendelian genes
BioMutasearch NOG
DgiDB (Drug Gene Interaction Database)NOG
DoCM (Curated mutations)NOG (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)NOG (select a term)
intoGenNOG
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)17:54671060-54672951  ENSG00000183691
CONAN: Copy Number AnalysisNOG 
Mutations and Diseases : HGMDNOG
OMIM184460    185800    186500    186570    602991    611377   
MedgenNOG
Genetic Testing Registry NOG
NextProtQ13253 [Medical]
TSGene9241
GENETestsNOG
Huge Navigator NOG [HugePedia]
snp3D : Map Gene to Disease9241
BioCentury BCIQNOG
ClinGenNOG
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD9241
Chemical/Pharm GKB GenePA31670
Clinical trialNOG
Miscellaneous
canSAR (ICR)NOG (select the gene name)
Probes
Litterature
PubMed88 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineNOG
EVEXNOG
GoPubMedNOG
iHOPNOG
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Sat May 28 11:13:53 CEST 2016

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