NORAD (non-coding RNA activated by DNA damage)

2018-02-01  

Identity

HGNC
LOCATION
20q11.23
LOCUSID
ALIAS
LINC00657

Other Information

Locus ID:

NCBI: 647979
MIM: 617037
HGNC: 44311
Ensembl: ENSG00000260032

Variants:

dbSNP: 647979
ClinVar: 647979
TCGA: ENSG00000260032
COSMIC: NORAD

RNA/Proteins

Expression (GTEx)

0
50
100
150
200
250
300

References

Pubmed IDYearTitleCitations
267248662016Noncoding RNA NORAD Regulates Genomic Stability by Sequestering PUMILIO Proteins.176
291219722017Long noncoding RNA NORAD, a novel competing endogenous RNA, enhances the hypoxia-induced epithelial-mesenchymal transition to promote metastasis in pancreatic cancer.44
297221042018Long noncoding RNA NORAD regulates transforming growth factor-β signaling and epithelial-to-mesenchymal transition-like phenotype.15
289190472017Long non-coding RNA 657 suppresses hepatocellular carcinoma cell growth by acting as a molecular sponge of miR-106a-5p to regulate PTEN expression.12
301192192018Long non-coding RNA NORAD upregulate SIP1 expression to promote cell proliferation and invasion in cervical cancer.11
293863302018SAM68 is required for regulation of Pumilio by the NORAD long noncoding RNA.10
309676312019LncRNA NORAD is repressed by the YAP pathway and suppresses lung and breast cancer metastasis by sequestering S100P.10
302273242018LINC00657 played oncogenic roles in esophageal squamous cell carcinoma by targeting miR-615-3p and JunB.9
300896992018Association between MicroRNA-373 and Long Noncoding RNA NORAD in Hepatitis C Virus-Infected Hepatocytes Impairs Wee1 Expression for Growth Promotion.5
271573882016NORAD: Defender of the Genome.4

Citation

Dessen P

NORAD (non-coding RNA activated by DNA damage)

Atlas Genet Cytogenet Oncol Haematol. 2018-02-01

Online version: http://atlasgeneticsoncology.org/gene/57385/norad