Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

NOS1AP (nitric oxide synthase 1 adaptor protein)

Identity

Alias_namesnitric oxide synthase 1 (neuronal) adaptor protein
Alias_symbol (synonym)KIAA0464
CAPON
Other alias6330408P19Rik
HGNC (Hugo) NOS1AP
LocusID (NCBI) 9722
Atlas_Id 47436
Location 1q23.3  [Link to chromosome band 1q23]
Location_base_pair Starts at 162332773 and ends at 162339813 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
F11R (1q23.3) / NOS1AP (1q23.3)NOS1AP (1q23.3) / ATF6 (1q23.3)NOS1AP (1q23.3) / C1orf226 (1q23.3)
NOS1AP (1q23.3) / COLGALT2 (1q25.3)NOS1AP (1q23.3) / F5 (1q24.2)NOS1AP (1q23.3) / HNRNPA2B1 (7p15.2)
NOS1AP (1q23.3) / LRRC52 (1q24.1)NOS1AP (1q23.3) / MROH9 (1q24.3)NOS1AP (1q23.3) / NOS1AP (1q23.3)
PTPRU (1p35.3) / NOS1AP (1q23.3)F11R 1q23.3 / NOS1AP 1q23.3NOS1AP 1q23.3 / ATF6 1q23.3
NOS1AP 1q23.3 C1orf129NOS1AP 1q23.3 / F5 1q24.2NOS1AP 1q23.3 GLT25D2
NOS1AP 1q23.3 / LRRC52 1q24.1PTPRU 1p35.3 / NOS1AP 1q23.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)NOS1AP   16859
Cards
Entrez_Gene (NCBI)NOS1AP  9722  nitric oxide synthase 1 adaptor protein
Aliases6330408P19Rik; CAPON
GeneCards (Weizmann)NOS1AP
Ensembl hg19 (Hinxton)ENSG00000198929 [Gene_View]  chr1:162332773-162339813 [Contig_View]  NOS1AP [Vega]
Ensembl hg38 (Hinxton)ENSG00000198929 [Gene_View]  chr1:162332773-162339813 [Contig_View]  NOS1AP [Vega]
ICGC DataPortalENSG00000198929
TCGA cBioPortalNOS1AP
AceView (NCBI)NOS1AP
Genatlas (Paris)NOS1AP
WikiGenes9722
SOURCE (Princeton)NOS1AP
Genetics Home Reference (NIH)NOS1AP
Genomic and cartography
GoldenPath hg19 (UCSC)NOS1AP  -     chr1:162332773-162339813 +  1q23.3   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)NOS1AP  -     1q23.3   [Description]    (hg38-Dec_2013)
EnsemblNOS1AP - 1q23.3 [CytoView hg19]  NOS1AP - 1q23.3 [CytoView hg38]
Mapping of homologs : NCBINOS1AP [Mapview hg19]  NOS1AP [Mapview hg38]
OMIM605551   
Gene and transcription
Genbank (Entrez)AB007933 AF037070 AI198232 AY841899 BC041382
RefSeq transcript (Entrez)NM_001126060 NM_001164757 NM_014697
RefSeq genomic (Entrez)NC_000001 NC_018912 NG_015979 NT_004487 NW_004929293
Consensus coding sequences : CCDS (NCBI)NOS1AP
Cluster EST : UnigeneHs.731942 [ NCBI ]
CGAP (NCI)Hs.731942
Alternative Splicing GalleryENSG00000198929
Gene ExpressionNOS1AP [ NCBI-GEO ]   NOS1AP [ EBI - ARRAY_EXPRESS ]   NOS1AP [ SEEK ]   NOS1AP [ MEM ]
Gene Expression Viewer (FireBrowse)NOS1AP [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)9722
GTEX Portal (Tissue expression)NOS1AP
Protein : pattern, domain, 3D structure
UniProt/SwissProtO75052   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO75052  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO75052
Splice isoforms : SwissVarO75052
PhosPhoSitePlusO75052
Domaine pattern : Prosite (Expaxy)PID (PS01179)   
Domains : Interpro (EBI)PH_dom-like    PTB/PI_dom   
Domain families : Pfam (Sanger)PID (PF00640)   
Domain families : Pfam (NCBI)pfam00640   
Domain families : Smart (EMBL)PTB (SM00462)  
Conserved Domain (NCBI)NOS1AP
DMDM Disease mutations9722
Blocks (Seattle)NOS1AP
SuperfamilyO75052
Human Protein AtlasENSG00000198929
Peptide AtlasO75052
HPRD12023
IPIIPI00514825   IPI00917608   IPI00944541   IPI00973959   IPI00978112   IPI00893882   
Protein Interaction databases
DIP (DOE-UCLA)O75052
IntAct (EBI)O75052
FunCoupENSG00000198929
BioGRIDNOS1AP
STRING (EMBL)NOS1AP
ZODIACNOS1AP
Ontologies - Pathways
QuickGOO75052
Ontology : AmiGOregulation of heart rate by chemical signal  protein binding  nucleus  mitochondrion  cytosol  caveola  positive regulation of gene expression  positive regulation of nitric oxide mediated signal transduction  Z disc  T-tubule  nuclear membrane  sarcoplasmic reticulum membrane  sarcolemma  regulation of apoptotic process  regulation of nitric oxide biosynthetic process  positive regulation of nitric oxide biosynthetic process  perinuclear region of cytoplasm  nitric-oxide synthase binding  regulation of nitric-oxide synthase activity  positive regulation of nitric-oxide synthase activity  regulation of ventricular cardiac muscle cell membrane repolarization  regulation of ventricular cardiac muscle cell membrane repolarization  regulation of cardiac muscle cell action potential  regulation of cardiac muscle cell action potential  positive regulation of potassium ion transmembrane transport  regulation of high voltage-gated calcium channel activity  positive regulation of delayed rectifier potassium channel activity  regulation of calcium ion transmembrane transport via high voltage-gated calcium channel  regulation of calcium ion transmembrane transport via high voltage-gated calcium channel  inward rectifier potassium channel complex  positive regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization  L-type voltage-gated calcium channel complex  positive regulation of peptidyl-cysteine S-nitrosylation  
Ontology : EGO-EBIregulation of heart rate by chemical signal  protein binding  nucleus  mitochondrion  cytosol  caveola  positive regulation of gene expression  positive regulation of nitric oxide mediated signal transduction  Z disc  T-tubule  nuclear membrane  sarcoplasmic reticulum membrane  sarcolemma  regulation of apoptotic process  regulation of nitric oxide biosynthetic process  positive regulation of nitric oxide biosynthetic process  perinuclear region of cytoplasm  nitric-oxide synthase binding  regulation of nitric-oxide synthase activity  positive regulation of nitric-oxide synthase activity  regulation of ventricular cardiac muscle cell membrane repolarization  regulation of ventricular cardiac muscle cell membrane repolarization  regulation of cardiac muscle cell action potential  regulation of cardiac muscle cell action potential  positive regulation of potassium ion transmembrane transport  regulation of high voltage-gated calcium channel activity  positive regulation of delayed rectifier potassium channel activity  regulation of calcium ion transmembrane transport via high voltage-gated calcium channel  regulation of calcium ion transmembrane transport via high voltage-gated calcium channel  inward rectifier potassium channel complex  positive regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization  L-type voltage-gated calcium channel complex  positive regulation of peptidyl-cysteine S-nitrosylation  
Pathways : KEGGCircadian entrainment   
NDEx NetworkNOS1AP
Atlas of Cancer Signalling NetworkNOS1AP
Wikipedia pathwaysNOS1AP
Orthology - Evolution
OrthoDB9722
GeneTree (enSembl)ENSG00000198929
Phylogenetic Trees/Animal Genes : TreeFamNOS1AP
HOVERGENO75052
HOGENOMO75052
Homologs : HomoloGeneNOS1AP
Homology/Alignments : Family Browser (UCSC)NOS1AP
Gene fusions - Rearrangements
Fusion : MitelmanF11R/NOS1AP [1q23.3/1q23.3]  [t(1;1)(q23;q23)]  
Fusion : MitelmanNOS1AP/ATF6 [1q23.3/1q23.3]  [t(1;1)(q23;q23)]  
Fusion : MitelmanNOS1AP/C1orf129 [1q23.3/t(1;1)(q23;q24)]  
Fusion : MitelmanNOS1AP/COLGALT2 [1q23.3/1q25.3]  [t(1;1)(q23;q25)]  
Fusion : MitelmanNOS1AP/F5 [1q23.3/1q24.2]  [t(1;1)(q23;q24)]  
Fusion : MitelmanNOS1AP/LRRC52 [1q23.3/1q24.1]  [t(1;1)(q23;q24)]  
Fusion : MitelmanNOS1AP/MROH9 [1q23.3/1q24.3]  [t(1;1)(q23;q24)]  
Fusion : MitelmanPTPRU/NOS1AP [1p35.3/1q23.3]  [t(1;1)(p35;q23)]  
Fusion: TCGAF11R 1q23.3 NOS1AP 1q23.3 LUAD
Fusion: TCGANOS1AP 1q23.3 ATF6 1q23.3 LUAD
Fusion: TCGANOS1AP 1q23.3 C1orf129 BRCA
Fusion: TCGANOS1AP 1q23.3 F5 1q24.2 LUAD
Fusion: TCGANOS1AP 1q23.3 GLT25D2 BRCA
Fusion: TCGANOS1AP 1q23.3 LRRC52 1q24.1 BLCA
Fusion: TCGAPTPRU 1p35.3 NOS1AP 1q23.3 KIRC
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerNOS1AP [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)NOS1AP
dbVarNOS1AP
ClinVarNOS1AP
1000_GenomesNOS1AP 
Exome Variant ServerNOS1AP
ExAC (Exome Aggregation Consortium)NOS1AP (select the gene name)
Genetic variants : HAPMAP9722
Genomic Variants (DGV)NOS1AP [DGVbeta]
DECIPHER (Syndromes)1:162332773-162339813  ENSG00000198929
CONAN: Copy Number AnalysisNOS1AP 
Mutations
ICGC Data PortalNOS1AP 
TCGA Data PortalNOS1AP 
Broad Tumor PortalNOS1AP
OASIS PortalNOS1AP [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICNOS1AP  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDNOS1AP
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch NOS1AP
DgiDB (Drug Gene Interaction Database)NOS1AP
DoCM (Curated mutations)NOS1AP (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)NOS1AP (select a term)
intoGenNOS1AP
Cancer3DNOS1AP(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM605551   
Orphanet14727   
MedgenNOS1AP
Genetic Testing Registry NOS1AP
NextProtO75052 [Medical]
TSGene9722
GENETestsNOS1AP
Huge Navigator NOS1AP [HugePedia]
snp3D : Map Gene to Disease9722
BioCentury BCIQNOS1AP
ClinGenNOS1AP
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD9722
Chemical/Pharm GKB GenePA142671259
Clinical trialNOS1AP
Miscellaneous
canSAR (ICR)NOS1AP (select the gene name)
Probes
Litterature
PubMed93 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineNOS1AP
EVEXNOS1AP
GoPubMedNOS1AP
iHOPNOS1AP
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Mar 14 13:19:07 CET 2017

Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.