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NOX5 (NADPH oxidase 5)

Identity

Alias_namesNADPH oxidase
Alias_symbol (synonym)NOX5A
NOX5B
Other alias-
HGNC (Hugo) NOX5
LocusID (NCBI) 79400
Atlas_Id 50047
Location 15q23  [Link to chromosome band 15q23]
Location_base_pair Starts at 69014695 and ends at 69057161 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
GLCE (15q23) / NOX5 (15q23)GLCE 15q23 / NOX5 15q23

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)NOX5   14874
Cards
Entrez_Gene (NCBI)NOX5  79400  NADPH oxidase 5
Aliases
GeneCards (Weizmann)NOX5
Ensembl hg19 (Hinxton)ENSG00000255346 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000255346 [Gene_View]  ENSG00000255346 [Sequence]  chr15:69014695-69057161 [Contig_View]  NOX5 [Vega]
ICGC DataPortalENSG00000255346
TCGA cBioPortalNOX5
AceView (NCBI)NOX5
Genatlas (Paris)NOX5
WikiGenes79400
SOURCE (Princeton)NOX5
Genetics Home Reference (NIH)NOX5
Genomic and cartography
GoldenPath hg38 (UCSC)NOX5  -     chr15:69014695-69057161 +  15q23   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)NOX5  -     15q23   [Description]    (hg19-Feb_2009)
EnsemblNOX5 - 15q23 [CytoView hg19]  NOX5 - 15q23 [CytoView hg38]
Mapping of homologs : NCBINOX5 [Mapview hg19]  NOX5 [Mapview hg38]
OMIM606572   
Gene and transcription
Genbank (Entrez)AF317889 AF325189 AF325190 AF353088 AF353089
RefSeq transcript (Entrez)NM_001184779 NM_001184780 NM_024505
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)NOX5
Cluster EST : UnigeneHs.657932 [ NCBI ]
CGAP (NCI)Hs.657932
Alternative Splicing GalleryENSG00000255346
Gene ExpressionNOX5 [ NCBI-GEO ]   NOX5 [ EBI - ARRAY_EXPRESS ]   NOX5 [ SEEK ]   NOX5 [ MEM ]
Gene Expression Viewer (FireBrowse)NOX5 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)79400
GTEX Portal (Tissue expression)NOX5
Human Protein AtlasENSG00000255346-NOX5 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96PH1   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96PH1  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96PH1
Splice isoforms : SwissVarQ96PH1
PhosPhoSitePlusQ96PH1
Domaine pattern : Prosite (Expaxy)EF_HAND_1 (PS00018)    EF_HAND_2 (PS50222)    FAD_FR (PS51384)   
Domains : Interpro (EBI)EF-hand-dom_pair    EF_Hand_1_Ca_BS    EF_hand_dom    FAD-bd_8    Fd_Rdtase_FAD-bd    Fe3_Rdtase_TM_dom    Fe_red_NAD-bd_6    NOX5    Riboflavin_synthase-like_b-brl   
Domain families : Pfam (Sanger)EF-hand_5 (PF13202)    EF-hand_6 (PF13405)    FAD_binding_8 (PF08022)    Ferric_reduct (PF01794)    NAD_binding_6 (PF08030)   
Domain families : Pfam (NCBI)pfam13202    pfam13405    pfam08022    pfam01794    pfam08030   
Domain families : Smart (EMBL)EFh (SM00054)  
Conserved Domain (NCBI)NOX5
DMDM Disease mutations79400
Blocks (Seattle)NOX5
SuperfamilyQ96PH1
Human Protein Atlas [tissue]ENSG00000255346-NOX5 [tissue]
Peptide AtlasQ96PH1
HPRD07359
IPIIPI00044456   IPI00740953   IPI00739568   IPI00739004   IPI00742061   IPI01020736   IPI00984198   
Protein Interaction databases
DIP (DOE-UCLA)Q96PH1
IntAct (EBI)Q96PH1
FunCoupENSG00000255346
BioGRIDNOX5
STRING (EMBL)NOX5
ZODIACNOX5
Ontologies - Pathways
QuickGOQ96PH1
Ontology : AmiGOangiogenesis  endothelial cell proliferation  calcium ion binding  endoplasmic reticulum membrane  apoptotic process  cell proliferation  regulation of proton transport  proton channel activity  integral component of membrane  superoxide-generating NADPH oxidase activity  superoxide-generating NADPH oxidase activity  heme binding  cellular response to oxidative stress  superoxide anion generation  regulation of fusion of sperm to egg plasma membrane  flavin adenine dinucleotide binding  NADP binding  cytokine secretion  oxidation-reduction process  cytoskeleton-dependent cytokinesis  proton transmembrane transport  
Ontology : EGO-EBIangiogenesis  endothelial cell proliferation  calcium ion binding  endoplasmic reticulum membrane  apoptotic process  cell proliferation  regulation of proton transport  proton channel activity  integral component of membrane  superoxide-generating NADPH oxidase activity  superoxide-generating NADPH oxidase activity  heme binding  cellular response to oxidative stress  superoxide anion generation  regulation of fusion of sperm to egg plasma membrane  flavin adenine dinucleotide binding  NADP binding  cytokine secretion  oxidation-reduction process  cytoskeleton-dependent cytokinesis  proton transmembrane transport  
NDEx NetworkNOX5
Atlas of Cancer Signalling NetworkNOX5
Wikipedia pathwaysNOX5
Orthology - Evolution
OrthoDB79400
GeneTree (enSembl)ENSG00000255346
Phylogenetic Trees/Animal Genes : TreeFamNOX5
HOVERGENQ96PH1
HOGENOMQ96PH1
Homologs : HomoloGeneNOX5
Homology/Alignments : Family Browser (UCSC)NOX5
Gene fusions - Rearrangements
Fusion PortalGLCE 15q23 NOX5 15q23 BRCA
Fusion : QuiverNOX5
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerNOX5 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)NOX5
dbVarNOX5
ClinVarNOX5
1000_GenomesNOX5 
Exome Variant ServerNOX5
ExAC (Exome Aggregation Consortium)ENSG00000255346
GNOMAD BrowserENSG00000255346
Varsome BrowserNOX5
Genetic variants : HAPMAP79400
Genomic Variants (DGV)NOX5 [DGVbeta]
DECIPHERNOX5 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisNOX5 
Mutations
ICGC Data PortalNOX5 
TCGA Data PortalNOX5 
Broad Tumor PortalNOX5
OASIS PortalNOX5 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICNOX5  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDNOX5
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch NOX5
DgiDB (Drug Gene Interaction Database)NOX5
DoCM (Curated mutations)NOX5 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)NOX5 (select a term)
intoGenNOX5
Cancer3DNOX5(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM606572   
Orphanet
DisGeNETNOX5
MedgenNOX5
Genetic Testing Registry NOX5
NextProtQ96PH1 [Medical]
TSGene79400
GENETestsNOX5
Target ValidationNOX5
Huge Navigator NOX5 [HugePedia]
snp3D : Map Gene to Disease79400
BioCentury BCIQNOX5
ClinGenNOX5
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD79400
Chemical/Pharm GKB GenePA31693
Clinical trialNOX5
Miscellaneous
canSAR (ICR)NOX5 (select the gene name)
Probes
Litterature
PubMed74 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineNOX5
EVEXNOX5
GoPubMedNOX5
iHOPNOX5
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Nov 6 11:26:41 CET 2018

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