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NOXA1 (NADPH oxidase activator 1)

Identity

Other namesNY-CO-31
SDCCAG31
p51NOX
HGNC (Hugo) NOXA1
LocusID (NCBI) 10811
Atlas_Id 41563
Location 9q34.3
Location_base_pair Starts at 140317847 and ends at 140328858 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)NOXA1   10668
Cards
Entrez_Gene (NCBI)NOXA1  10811  NADPH oxidase activator 1
GeneCards (Weizmann)NOXA1
Ensembl hg19 (Hinxton)ENSG00000188747 [Gene_View]  chr9:140317847-140328858 [Contig_View]  NOXA1 [Vega]
Ensembl hg38 (Hinxton)ENSG00000188747 [Gene_View]  chr9:140317847-140328858 [Contig_View]  NOXA1 [Vega]
ICGC DataPortalENSG00000188747
TCGA cBioPortalNOXA1
AceView (NCBI)NOXA1
Genatlas (Paris)NOXA1
WikiGenes10811
SOURCE (Princeton)NOXA1
Genomic and cartography
GoldenPath hg19 (UCSC)NOXA1  -     chr9:140317847-140328858 +  9q34.3   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)NOXA1  -     9q34.3   [Description]    (hg38-Dec_2013)
EnsemblNOXA1 - 9q34.3 [CytoView hg19]  NOXA1 - 9q34.3 [CytoView hg38]
Mapping of homologs : NCBINOXA1 [Mapview hg19]  NOXA1 [Mapview hg38]
OMIM611255   
Gene and transcription
Genbank (Entrez)AB095031 AF039697 AI860821 AK055812 AK098341
RefSeq transcript (Entrez)NM_001256067 NM_001256068 NM_006647
RefSeq genomic (Entrez)NC_000009 NC_018920 NT_008470 NW_004929369
Consensus coding sequences : CCDS (NCBI)NOXA1
Cluster EST : UnigeneHs.495554 [ NCBI ]
CGAP (NCI)Hs.495554
Alternative Splicing : Fast-db (Paris)GSHG0030616
Alternative Splicing GalleryENSG00000188747
Gene ExpressionNOXA1 [ NCBI-GEO ]     NOXA1 [ SEEK ]   NOXA1 [ MEM ]
SOURCE (Princeton)Expression in : [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ86UR1 (Uniprot)
NextProtQ86UR1  [Medical]  [Publications]
With graphics : InterProQ86UR1
Splice isoforms : SwissVarQ86UR1 (Swissvar)
Domaine pattern : Prosite (Expaxy)PB1 (PS51745)    SH3 (PS50002)    TPR_REGION (PS50293)   
Domains : Interpro (EBI)OPR_PB1    SH3_domain    TPR-contain_dom    TPR-like_helical_dom    TPR_2    TPR_repeat   
Related proteins : CluSTrQ86UR1
Domain families : Pfam (Sanger)PB1 (PF00564)    SH3_1 (PF00018)    TPR_2 (PF07719)   
Domain families : Pfam (NCBI)pfam00564    pfam00018    pfam07719   
Domain families : Smart (EMBL)PB1 (SM00666)  SH3 (SM00326)  TPR (SM00028)  
DMDM Disease mutations10811
Blocks (Seattle)Q86UR1
Human Protein AtlasENSG00000188747
Peptide AtlasQ86UR1
HPRD17644
IPIIPI00879507   IPI00216835   IPI00654838   IPI00848144   
Protein Interaction databases
DIP (DOE-UCLA)Q86UR1
IntAct (EBI)Q86UR1
FunCoupENSG00000188747
BioGRIDNOXA1
IntegromeDBNOXA1
STRING (EMBL)NOXA1
Ontologies - Pathways
QuickGOQ86UR1
Ontology : AmiGOprotein binding  cytosol  superoxide metabolic process  small GTPase mediated signal transduction  regulation of hydrogen peroxide metabolic process  superoxide-generating NADPH oxidase activator activity  superoxide-generating NADPH oxidase activator activity  SH3 domain binding  enzyme binding  NADPH oxidase complex  positive regulation of catalytic activity  Rac GTPase binding  regulation of respiratory burst  
Ontology : EGO-EBIprotein binding  cytosol  superoxide metabolic process  small GTPase mediated signal transduction  regulation of hydrogen peroxide metabolic process  superoxide-generating NADPH oxidase activator activity  superoxide-generating NADPH oxidase activator activity  SH3 domain binding  enzyme binding  NADPH oxidase complex  positive regulation of catalytic activity  Rac GTPase binding  regulation of respiratory burst  
Protein Interaction DatabaseNOXA1
DoCM (Curated mutations)NOXA1
Wikipedia pathwaysNOXA1
Gene fusion - Rearrangements
Gene fusion: TCGA
Polymorphisms : SNP, variants
NCBI Variation ViewerNOXA1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)NOXA1
dbVarNOXA1
ClinVarNOXA1
1000_GenomesNOXA1 
Exome Variant ServerNOXA1
SNP (GeneSNP Utah)NOXA1
SNP : HGBaseNOXA1
Genetic variants : HAPMAPNOXA1
Genomic Variants (DGV)NOXA1 [DGVbeta]
Mutations
ICGC Data PortalNOXA1 
TCGA Data PortalNOXA1 
Tumor PortalNOXA1
Somatic Mutations in Cancer : COSMICNOXA1 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)9:140317847-140328858
CONAN: Copy Number AnalysisNOXA1 
Mutations and Diseases : HGMDNOXA1
OMIM611255   
MedgenNOXA1
NextProtQ86UR1 [Medical]
GENETestsNOXA1
Disease Genetic AssociationNOXA1
Huge Navigator NOXA1 [HugePedia]  NOXA1 [HugeCancerGEM]
snp3D : Map Gene to Disease10811
DGIdb (Drug Gene Interaction db)NOXA1
BioCentury BCIQNOXA1
General knowledge
Homologs : HomoloGeneNOXA1
Homology/Alignments : Family Browser (UCSC)NOXA1
Phylogenetic Trees/Animal Genes : TreeFamNOXA1
Chemical/Protein Interactions : CTD10811
Chemical/Pharm GKB GenePA35598
Clinical trialNOXA1
Cancer Resource (Charite)ENSG00000188747
Other databases
Probes
Litterature
PubMed29 Pubmed reference(s) in Entrez
CoreMineNOXA1
GoPubMedNOXA1
iHOPNOXA1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated02-2015Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Sat Jun 27 12:00:06 CEST 2015

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