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NOXA1 (NADPH oxidase activator 1)

Identity

Other namesNY-CO-31
SDCCAG31
p51NOX
HGNC (Hugo) NOXA1
LocusID (NCBI) 10811
Location 9q34.3
Location_base_pair Starts at 140317847 and ends at 140328858 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)NOXA1   10668
Cards
Entrez_Gene (NCBI)NOXA1  10811  NADPH oxidase activator 1
GeneCards (Weizmann)NOXA1
Ensembl (Hinxton)ENSG00000188747 [Gene_View]  chr9:140317847-140328858 [Contig_View]  NOXA1 [Vega]
ICGC DataPortalENSG00000188747
cBioPortalNOXA1
AceView (NCBI)NOXA1
Genatlas (Paris)NOXA1
WikiGenes10811
SOURCE (Princeton)NM_001256067 NM_001256068 NM_006647
Genomic and cartography
GoldenPath (UCSC)NOXA1  -  9q34.3   chr9:140317847-140328858 +  9q34.3   [Description]    (hg19-Feb_2009)
EnsemblNOXA1 - 9q34.3 [CytoView]
Mapping of homologs : NCBINOXA1 [Mapview]
OMIM611255   
Gene and transcription
Genbank (Entrez)AB095031 AF039697 AI860821 AK055812 AK098341
RefSeq transcript (Entrez)NM_001256067 NM_001256068 NM_006647
RefSeq genomic (Entrez)AC_000141 NC_000009 NC_018920 NT_008470 NW_001839245 NW_004929369
Consensus coding sequences : CCDS (NCBI)NOXA1
Cluster EST : UnigeneHs.495554 [ NCBI ]
CGAP (NCI)Hs.495554
Alternative Splicing : Fast-db (Paris)GSHG0030616
Alternative Splicing GalleryENSG00000188747
Gene ExpressionNOXA1 [ NCBI-GEO ]     NOXA1 [ SEEK ]   NOXA1 [ MEM ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ86UR1 (Uniprot)
NextProtQ86UR1  [Medical]
With graphics : InterProQ86UR1
Splice isoforms : SwissVarQ86UR1 (Swissvar)
Domaine pattern : Prosite (Expaxy)SH3 (PS50002)    TPR_REGION (PS50293)   
Domains : Interpro (EBI)OPR_PB1 [organisation]   SH3_domain [organisation]   TPR-contain_dom [organisation]   TPR-like_helical [organisation]   TPR_2 [organisation]   TPR_repeat [organisation]  
Related proteins : CluSTrQ86UR1
Domain families : Pfam (Sanger)PB1 (PF00564)    SH3_1 (PF00018)    TPR_2 (PF07719)   
Domain families : Pfam (NCBI)pfam00564    pfam00018    pfam07719   
Domain families : Smart (EMBL)PB1 (SM00666)  SH3 (SM00326)  TPR (SM00028)  
DMDM Disease mutations10811
Blocks (Seattle)Q86UR1
Human Protein AtlasENSG00000188747 [gene] [tissue] [antibody] [cell] [cancer]
Peptide AtlasQ86UR1
HPRD17644
IPIIPI00879507   IPI00216835   IPI00654838   IPI00848144   
Protein Interaction databases
DIP (DOE-UCLA)Q86UR1
IntAct (EBI)Q86UR1
FunCoupENSG00000188747
BioGRIDNOXA1
InParanoidQ86UR1
Interologous Interaction database Q86UR1
IntegromeDBNOXA1
STRING (EMBL)NOXA1
Ontologies - Pathways
Ontology : AmiGOprotein binding  cytoplasm  superoxide metabolic process  regulation of hydrogen peroxide metabolic process  superoxide-generating NADPH oxidase activator activity  superoxide-generating NADPH oxidase activator activity  SH3 domain binding  enzyme binding  NADPH oxidase complex  positive regulation of catalytic activity  positive regulation of catalytic activity  positive regulation of catalytic activity  Rac GTPase binding  regulation of respiratory burst  
Ontology : EGO-EBIprotein binding  cytoplasm  superoxide metabolic process  regulation of hydrogen peroxide metabolic process  superoxide-generating NADPH oxidase activator activity  superoxide-generating NADPH oxidase activator activity  SH3 domain binding  enzyme binding  NADPH oxidase complex  positive regulation of catalytic activity  positive regulation of catalytic activity  positive regulation of catalytic activity  Rac GTPase binding  regulation of respiratory burst  
Protein Interaction DatabaseNOXA1
Wikipedia pathwaysNOXA1
Gene fusion - rearrangments
Polymorphisms : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)NOXA1
snp3D : Map Gene to Disease10811
SNP (GeneSNP Utah)NOXA1
SNP : HGBaseNOXA1
Genetic variants : HAPMAPNOXA1
Exome VariantNOXA1
1000_GenomesNOXA1 
ICGC programENSG00000188747 
Somatic Mutations in Cancer : COSMICNOXA1 
CONAN: Copy Number AnalysisNOXA1 
Mutations and Diseases : HGMDNOXA1
Genomic VariantsNOXA1  NOXA1 [DGVbeta]
dbVarNOXA1
ClinVarNOXA1
Pred. of missensesPolyPhen-2  SIFT(SG)  SIFT(JCVI)  Align-GVGD  MutAssessor  Mutanalyser  
Pred. splicesGeneSplicer  Human Splicing Finder  MaxEntScan  
Diseases
OMIM611255   
MedgenNOXA1
GENETestsNOXA1
Disease Genetic AssociationNOXA1
Huge Navigator NOXA1 [HugePedia]  NOXA1 [HugeCancerGEM]
General knowledge
Homologs : HomoloGeneNOXA1
Homology/Alignments : Family Browser (UCSC)NOXA1
Phylogenetic Trees/Animal Genes : TreeFamNOXA1
Chemical/Protein Interactions : CTD10811
Chemical/Pharm GKB GenePA35598
Clinical trialNOXA1
Cancer Resource (Charite)ENSG00000188747
Other databases
Probes
Litterature
PubMed28 Pubmed reference(s) in Entrez
CoreMineNOXA1
iHOPNOXA1
OncoSearchNOXA1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Sat Jul 26 14:41:30 CEST 2014

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