NP (nucleoside phosphorylase)

Identity

Other names	FLJ94043
	FLJ97288
	FLJ97312
	MGC117396
	MGC125915
	MGC125916
	PNP
	PRO1837
	PUNP
HGNC	NP
Location	14q11.2
Location_base_pair	Starts at 20007382 and ends at 20015088 bp from pter ( according to hg18-March_2006).
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
HGNC	NP   7892
Entrez_Gene	NP  4860  nucleoside phosphorylase
	Cards
GeneCards	NP
Ensembl	ENSG00000198805 [Gene_View]  NP [Vega]
Genatlas	NP
	Genomic and cartography
GoldenPath	NP  -  14q11.2   chr14:20007382-20015088 +  14q11.2   [Description]    (hg18-March_2006)
Ensembl	NP - 14q11.2 [CytoView]
NCBI	Mapview
OMIM	164050 Disease map [OMIM]
HomoloGene	NP
	Gene and transcription
Genbank	AK098544 [ ENTREZ ]
Genbank	AK126154 [ ENTREZ ]
Genbank	AK307340 [ ENTREZ ]
Genbank	AK307364 [ ENTREZ ]
Genbank	AK313490 [ ENTREZ ]
RefSeq	NM_000270 [ SRS ]    NM_000270 [ ENTREZ ]
RefSeq	AC_000057 [ SRS ]    AC_000057 [ ENTREZ ]
RefSeq	AC_000146 [ SRS ]    AC_000146 [ ENTREZ ]
RefSeq	NC_000014 [ SRS ]    NC_000014 [ ENTREZ ]
RefSeq	NT_026437 [ SRS ]    NT_026437 [ ENTREZ ]
RefSeq	NW_001838110 [ SRS ]    NW_001838110 [ ENTREZ ]
RefSeq	NW_925539 [ SRS ]    NW_925539 [ ENTREZ ]
CCDS	NP CCDS - NCBI
AceView	NP AceView - NCBI
Unigene	Hs.75514 [ SRS ]    Hs.75514 [ NCBI ]
Fast-db	18 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	P00491 [ SRS]    P00491 [ EXPASY ]     P00491 [ INTERPRO ]     P00491 [ UNIPROT ] P00491 [ VarSplice FASTA ]
Prosite	PS01240 PNP_MTAP_2 [ SRS ]    PS01240 PNP_MTAP_2 [ Expasy ]
Interpro	IPR001369 Mtap_PNP [ SRS ]    IPR001369 Mtap_PNP [ EBI ]
Interpro	IPR011268 PNPHPUNA_XAPA [ SRS ]    IPR011268 PNPHPUNA_XAPA [ EBI ]
Interpro	IPR011270 Pur_Nuc_Pase_Ino/Guo-sp [ SRS ]    IPR011270 Pur_Nuc_Pase_Ino/Guo-sp [ EBI ]
CluSTr	P00491
Pfam	PF00896 Mtap_PNP [ SRS ]    PF00896 Mtap_PNP [ Sanger ]    pfam00896 [ NCBI-CDD ]
Blocks	P00491
PDB	1M73 [ SRS ]    1M73 [ PdbSum ],   1M73 [ IMB ]   1M73 [ RSDB ]
PDB	1PF7 [ SRS ]    1PF7 [ PdbSum ],   1PF7 [ IMB ]   1PF7 [ RSDB ]
PDB	1PWY [ SRS ]    1PWY [ PdbSum ],   1PWY [ IMB ]   1PWY [ RSDB ]
PDB	1RCT [ SRS ]    1RCT [ PdbSum ],   1RCT [ IMB ]   1RCT [ RSDB ]
PDB	1RFG [ SRS ]    1RFG [ PdbSum ],   1RFG [ IMB ]   1RFG [ RSDB ]
PDB	1RR6 [ SRS ]    1RR6 [ PdbSum ],   1RR6 [ IMB ]   1RR6 [ RSDB ]
PDB	1RSZ [ SRS ]    1RSZ [ PdbSum ],   1RSZ [ IMB ]   1RSZ [ RSDB ]
PDB	1RT9 [ SRS ]    1RT9 [ PdbSum ],   1RT9 [ IMB ]   1RT9 [ RSDB ]
PDB	1ULA [ SRS ]    1ULA [ PdbSum ],   1ULA [ IMB ]   1ULA [ RSDB ]
PDB	1ULB [ SRS ]    1ULB [ PdbSum ],   1ULB [ IMB ]   1ULB [ RSDB ]
PDB	1V2H [ SRS ]    1V2H [ PdbSum ],   1V2H [ IMB ]   1V2H [ RSDB ]
PDB	1V3Q [ SRS ]    1V3Q [ PdbSum ],   1V3Q [ IMB ]   1V3Q [ RSDB ]
PDB	1V41 [ SRS ]    1V41 [ PdbSum ],   1V41 [ IMB ]   1V41 [ RSDB ]
PDB	1V45 [ SRS ]    1V45 [ PdbSum ],   1V45 [ IMB ]   1V45 [ RSDB ]
PDB	1YRY [ SRS ]    1YRY [ PdbSum ],   1YRY [ IMB ]   1YRY [ RSDB ]
PDB	2A0W [ SRS ]    2A0W [ PdbSum ],   2A0W [ IMB ]   2A0W [ RSDB ]
PDB	2A0X [ SRS ]    2A0X [ PdbSum ],   2A0X [ IMB ]   2A0X [ RSDB ]
PDB	2A0Y [ SRS ]    2A0Y [ PdbSum ],   2A0Y [ IMB ]   2A0Y [ RSDB ]
PDB	2OC4 [ SRS ]    2OC4 [ PdbSum ],   2OC4 [ IMB ]   2OC4 [ RSDB ]
PDB	2OC9 [ SRS ]    2OC9 [ PdbSum ],   2OC9 [ IMB ]   2OC9 [ RSDB ]
PDB	2ON6 [ SRS ]    2ON6 [ PdbSum ],   2ON6 [ IMB ]   2ON6 [ RSDB ]
PDB	2Q7O [ SRS ]    2Q7O [ PdbSum ],   2Q7O [ IMB ]   2Q7O [ RSDB ]
PDB	3BGS [ SRS ]    3BGS [ PdbSum ],   3BGS [ IMB ]   3BGS [ RSDB ]
HPRD	01247
	Protein Interaction databases
DIP	P00491
IntAct	P00491
	Polymorphism : SNP, mutations, diseases
OMIM	164050    [ map ]
GENETests	164050
SNP	NP [dbSNP-NCBI]
SNP	NM_000270 [SNP-NCI]
SNP	NP [GeneSNPs - Utah]  NP] [HGBASE - SRS]
HAPMAP	NP [HAPMAP]
COSMIC	NP [Somatic mutation (COSMIC-CGP-Sanger)]
HGMD	NP
Genetic Association	NP
CDC HuGE	NP
	General knowledge
Family Browser	NP [UCSC Family Browser]
SOURCE	NM_000270
SMD	Hs.75514
SAGE	Hs.75514
Enzyme	2.4.2.1 [ Enzyme-Expasy ]   2.4.2.1 [ Enzyme-SRS ]   2.4.2.1 [ IntEnz-EBI ]   2.4.2.1 [ BRENDA ]   2.4.2.1 [ KEGG ]
GO	purine-nucleoside phosphorylase activity [Amigo]  purine-nucleoside phosphorylase activity
GO	purine-nucleoside phosphorylase activity [Amigo]  purine-nucleoside phosphorylase activity
GO	purine-nucleoside phosphorylase activity [Amigo]  purine-nucleoside phosphorylase activity
GO	cytosol [Amigo]  cytosol
GO	nucleobase, nucleoside, nucleotide and nucleic acid metabolic process [Amigo]  nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
GO	nucleobase, nucleoside, nucleotide and nucleic acid metabolic process [Amigo]  nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
GO	inosine catabolic process [Amigo]  inosine catabolic process
GO	DNA modification [Amigo]  DNA modification
GO	urate biosynthetic process [Amigo]  urate biosynthetic process
GO	positive regulation of T cell proliferation [Amigo]  positive regulation of T cell proliferation
GO	positive regulation of alpha-beta T cell differentiation [Amigo]  positive regulation of alpha-beta T cell differentiation
KEGG	Purine metabolism
KEGG	Pyrimidine metabolism
KEGG	Nicotinate and nicotinamide metabolism
PubGene	NP
TreeFam	NP
CTD	4860 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	NP Related clones (RZPD - Berlin)
	PubMed
PubMed	35 Pubmed reference(s) in Entrez

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Thu Nov 27 14:00:41 2008