Atlas of Genetics and Cytogenetics in Oncology and Haematology

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NPAS2 (neuronal PAS domain protein 2)

Identity

Other namesMOP4
PASD4
bHLHe9
HGNC (Hugo) NPAS2
LocusID (NCBI) 4862
Location 2q11.2
Location_base_pair Starts at 101436613 and ends at 101613287 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)NPAS2   7895
Entrez_Gene (NCBI)NPAS2  4862  neuronal PAS domain protein 2
Cards
GeneCards (Weizmann)NPAS2
Ensembl (Hinxton)ENSG00000170485 [Gene_View]  chr2:101436613-101613287 [Contig_View]  NPAS2 [Vega]
AceView (NCBI)NPAS2
Genatlas (Paris)NPAS2
SOURCE (Stanford)NM_002518
Genomic and cartography
GoldenPath (UCSC)NPAS2  -  2q11.2   chr2:101436613-101613287 +  2q11.2   [Description]    (hg19-Feb_2009)
EnsemblNPAS2 - 2q11.2 [CytoView]
Mapping of homologs : NCBINPAS2 [Mapview]
OMIM603347   
Gene and transcription
Genbank (Entrez)AK026791 AK091939 AK095806 AK128586 AK226093
RefSeq transcript (SRS)NM_002518
RefSeq transcript (Entrez)NM_002518
RefSeq genomic (SRS)AC_000134 NC_000002 NC_018913 NG_023259 NT_022171 NW_001838818 NW_004078008
RefSeq genomic (Entrez)AC_000134 NC_000002 NC_018913 NG_023259 NT_022171 NW_001838818 NW_004078008
Consensus coding sequences : CCDS (NCBI)NPAS2
Cluster EST : UnigeneHs.705895 [ SRS ] Hs.705895 [ NCBI ]
CGAP (NCI)Hs.705895
Alternative Splicing : Fast-db (Paris)GSHG0016712
Alternative Splicing GalleryENSG00000170485
Gene ExpressionNPAS2 [ NCBI-GEO ]   NPAS2 [ EBI - ARRAY_EXPRESS ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ99743 (SRS) Q99743 (Uniprot)
NextProtQ99743
With graphics : InterProQ99743
Splice isoforms : SwissVarQ99743(Swissvar)
Domaine pattern : Prosite (SRS)BHLH (PS50888)    PAC (PS50113)    PAS (PS50112)   
Domaine pattern : Prosite (Expaxy)BHLH (PS50888)    PAC (PS50113)    PAS (PS50112)   
Domains : Interpro (SRS)HLH_dom    Nuc_translocat    PAC    PAS    PAS_fold    PAS_fold_3   
Domains : Interpro (EBI)HLH_dom    Nuc_translocat    PAC    PAS    PAS_fold    PAS_fold_3   
Related proteins : CluSTrQ99743
Domain families : Pfam (SRS)HLH (PF00010)    PAS (PF00989)    PAS_3 (PF08447)   
Domain families : Pfam (Sanger)HLH (PF00010)    PAS (PF00989)    PAS_3 (PF08447)   
Domain families : Pfam (NCBI)pfam00010    pfam00989    pfam08447   
Domain families : Smart (EMBL)HLH (SM00353)  PAC (SM00086)  PAS (SM00091)  
DMDM4862
Blocks (Seattle)Q99743
Human Protein AtlasENSG00000170485
HPRD09137
IPIIPI00956556   IPI00916781   IPI00386144   IPI00746650   IPI00915815   IPI00915931   IPI00917145   IPI00917334   
Protein Interaction databases
DIP (DOE-UCLA)Q99743
IntAct (EBI)Q99743
FunCoupENSG00000170485
REACTOMENPAS2
Protein Interaction Database4862
BioGRIDNPAS2
InParanoidQ99743
Interologous Interaction database Q99743
IntegromeDBNPAS2
Polymorphism : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)NPAS2
SNP (GeneSNP Utah)NPAS2
SNP : HGBaseNPAS2
Genetic variants : HAPMAPNPAS2
Somatic Mutations in Cancer : COSMICNPAS2 
CONAN: Copy Number AnalysisNPAS2 
Mutations and Diseases : HGMDNPAS2
OMIM603347   
GENETests603347   
Disease Genetic AssociationNPAS2
Huge Navigator NPAS2 [HugePedia]  NPAS2 [HugeCancerGEM]
Genomic VariantsNPAS2  NPAS2 [DGVbeta]
snp3D : Map Gene to Disease4862
General knowledge
Homologs : HomoloGeneNPAS2
Homology/Alignments : Family Browser (UCSC)NPAS2
Phylogenetic Trees/Animal Genes : TreeFamNPAS2
Chemical/Protein Interactions : CTD4862
Chemical/Pharm GKB GenePA31696
Clinical trialNPAS2
Cancer Resource (Charite)ENSG00000170485
Ontology : AmiGODNA binding  sequence-specific DNA binding transcription factor activity  signal transducer activity  transcription factor complex  cytosol  transcription, DNA-dependent  central nervous system development  circadian sleep/wake cycle  cellular lipid metabolic process  small molecule metabolic process  locomotor rhythm  positive regulation of transcription from RNA polymerase II promoter  protein dimerization activity  Hsp90 protein binding  
Ontology : EGO-EBIDNA binding  sequence-specific DNA binding transcription factor activity  signal transducer activity  transcription factor complex  cytosol  transcription, DNA-dependent  central nervous system development  circadian sleep/wake cycle  cellular lipid metabolic process  small molecule metabolic process  locomotor rhythm  positive regulation of transcription from RNA polymerase II promoter  protein dimerization activity  Hsp90 protein binding  
Pathways : KEGGCircadian rhythm
Other databases
Probes
Litterature
PubMed42 Pubmed reference(s) in Entrez
PubGeneNPAS2
iHOPNPAS2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated01-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed May 1 12:29:31 CEST 2013
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