| ARID4A (14q23.1) / NPAS3 (14q13.1) | FAM114A1 (4p14) / NPAS3 (14q13.1) | FOXG1 (14q12) / NPAS3 (14q13.1) |
|
MIPOL1 (14q13.3) / NPAS3 (14q13.1) | NPAS3 (14q13.1) / AKAP6 (14q12) | NPAS3 (14q13.1) / NPAS3 (14q13.1) |
|
NPAS3 (14q13.1) / OXA1L (14q11.2) | RGS6 (14q24.2) / NPAS3 (14q13.1) | RP11-468E2.1 () / NPAS3 (14q13.1) |
|
SMO (7q32.1) / NPAS3 (14q13.1) | ARID4A 14q23.1 / NPAS3 14q13.1 | MIPOL1 14q13.3 / NPAS3 14q13.1 |
|
NPAS3 14q13.1 / AKAP6 14q12 | RGS6 14q24.2 / NPAS3 14q13.1 | RP11-468E2.1 NPAS3 14q13.1 |
|
| Nomenclature |
HGNC (Hugo) | NPAS3 19311 |
| Cards |
Entrez_Gene (NCBI) | NPAS3 64067 neuronal PAS domain protein 3 |
Aliases | MOP6; PASD6; bHLHe12 |
GeneCards (Weizmann) | NPAS3 |
Ensembl hg19 (Hinxton) | ENSG00000151322 [Gene_View] |
Ensembl hg38 (Hinxton) | ENSG00000151322 [Gene_View]  ENSG00000151322 [Sequence] chr14:32939253-33804176 [Contig_View] NPAS3 [Vega] |
ICGC DataPortal | ENSG00000151322 |
TCGA cBioPortal | NPAS3 |
AceView (NCBI) | NPAS3 |
Genatlas (Paris) | NPAS3 |
WikiGenes | 64067 |
SOURCE (Princeton) | NPAS3 |
Genetics Home Reference (NIH) | NPAS3 |
| Genomic and cartography |
GoldenPath hg38 (UCSC) | NPAS3 - chr14:32939253-33804176 + 14q13.1 [Description] (hg38-Dec_2013) |
GoldenPath hg19 (UCSC) | NPAS3 - 14q13.1 [Description] (hg19-Feb_2009) |
GoldenPath | NPAS3 - 14q13.1 [CytoView hg19] NPAS3 - 14q13.1 [CytoView hg38] |
ImmunoBase | ENSG00000151322 |
Mapping of homologs : NCBI | NPAS3 [Mapview hg19] NPAS3 [Mapview hg38] |
OMIM | 609430 |
| Gene and transcription |
Genbank (Entrez) | AB054575 AB054576 AB055962 AF164438 AI811363 |
RefSeq transcript (Entrez) | NM_001164749 NM_001165893 NM_022123 NM_173159 |
RefSeq genomic (Entrez) | |
Consensus coding sequences : CCDS (NCBI) | NPAS3 |
Cluster EST : Unigene | Hs.675475 [ NCBI ] |
CGAP (NCI) | Hs.675475 |
Alternative Splicing Gallery | ENSG00000151322 |
Gene Expression | NPAS3 [ NCBI-GEO ] NPAS3 [ EBI - ARRAY_EXPRESS ]
NPAS3 [ SEEK ] NPAS3 [ MEM ] |
Gene Expression Viewer (FireBrowse) | NPAS3 [ Firebrowse - Broad ] |
SOURCE (Princeton) | Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60] |
Genevestigator | Expression in : [tissues]  [cell-lines]  [cancer]  [perturbations]   |
BioGPS (Tissue expression) | 64067 |
GTEX Portal (Tissue expression) | NPAS3 |
Human Protein Atlas | ENSG00000151322-NPAS3 [pathology] [cell] [tissue] |
| Protein : pattern, domain, 3D structure |
UniProt/SwissProt | Q8IXF0 [function] [subcellular_location] [family_and_domains] [pathology_and_biotech] [ptm_processing] [expression] [interaction] |
NextProt | Q8IXF0 [Sequence] [Exons] [Medical] [Publications] |
With graphics : InterPro | Q8IXF0 |
Splice isoforms : SwissVar | Q8IXF0 |
PhosPhoSitePlus | Q8IXF0 |
Domaine pattern : Prosite (Expaxy) | BHLH (PS50888) PAS (PS50112) |
Domains : Interpro (EBI) | bHLH_dom HLH_DNA-bd_sf PAS PAS-like_dom_sf PAS_fold PAS_fold_3 |
Domain families : Pfam (Sanger) | PAS (PF00989) PAS_3 (PF08447) |
Domain families : Pfam (NCBI) | pfam00989 pfam08447 |
Domain families : Smart (EMBL) | HLH (SM00353) PAS (SM00091) |
Conserved Domain (NCBI) | NPAS3 |
DMDM Disease mutations | 64067 |
Blocks (Seattle) | NPAS3 |
Superfamily | Q8IXF0 |
Human Protein Atlas [tissue] | ENSG00000151322-NPAS3 [tissue] |
Peptide Atlas | Q8IXF0 |
HPRD | 11400 |
IPI | IPI00217513 IPI00394963 IPI00394964 IPI00394965 IPI00394966 IPI00394967 IPI01021601 IPI01020861 IPI01021261 IPI01021732 IPI01021051 IPI01021176 |
| Protein Interaction databases |
DIP (DOE-UCLA) | Q8IXF0 |
IntAct (EBI) | Q8IXF0 |
FunCoup | ENSG00000151322 |
BioGRID | NPAS3 |
STRING (EMBL) | NPAS3 |
ZODIAC | NPAS3 |
| Ontologies - Pathways |
QuickGO | Q8IXF0 |
Ontology : AmiGO | DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA binding nucleus nucleoplasm cytosol regulation of transcription by RNA polymerase II positive regulation of transcription, DNA-templated positive regulation of transcription by RNA polymerase II protein heterodimerization activity |
Ontology : EGO-EBI | DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA binding nucleus nucleoplasm cytosol regulation of transcription by RNA polymerase II positive regulation of transcription, DNA-templated positive regulation of transcription by RNA polymerase II protein heterodimerization activity |
NDEx Network | NPAS3 |
Atlas of Cancer Signalling Network | NPAS3 |
Wikipedia pathways | NPAS3 |
| Orthology - Evolution |
OrthoDB | 64067 |
GeneTree (enSembl) | ENSG00000151322 |
Phylogenetic Trees/Animal Genes : TreeFam | NPAS3 |
HOGENOM | Q8IXF0 |
Homologs : HomoloGene | NPAS3 |
Homology/Alignments : Family Browser (UCSC) | NPAS3 |
| Gene fusions - Rearrangements |
Fusion : Mitelman | ARID4A/NPAS3 [14q23.1/14q13.1]  [t(14;14)(q13;q23)] |
Fusion : Mitelman | FOXG1/NPAS3 [14q12/14q13.1]  [t(14;14)(q12;q13)] |
Fusion : Mitelman | NPAS3/AKAP6 [14q13.1/14q12]  [t(14;14)(q12;q13)] |
Fusion : Mitelman | NPAS3/OXA1L [14q13.1/14q11.2]  [t(14;14)(q11;q13)] |
Fusion : Mitelman | RGS6/NPAS3 [14q24.2/14q13.1]  [t(14;14)(q13;q24)] |
Fusion Portal | ARID4A 14q23.1 NPAS3 14q13.1 LUAD |
Fusion Portal | MIPOL1 14q13.3 NPAS3 14q13.1 LUAD |
Fusion Portal | NPAS3 14q13.1 AKAP6 14q12 LUAD |
Fusion Portal | RGS6 14q24.2 NPAS3 14q13.1 LGG |
Fusion Portal | RP11-468E2.1 NPAS3 14q13.1 LUAD |
Fusion : Quiver | NPAS3 |
| Polymorphisms : SNP and Copy number variants |
NCBI Variation Viewer | NPAS3 [hg38] |
dbSNP Single Nucleotide Polymorphism (NCBI) | NPAS3 |
dbVar | NPAS3 |
ClinVar | NPAS3 |
1000_Genomes | NPAS3 |
Exome Variant Server | NPAS3 |
ExAC (Exome Aggregation Consortium) | ENSG00000151322 |
GNOMAD Browser | ENSG00000151322 |
Varsome Browser | NPAS3 |
Genetic variants : HAPMAP | 64067 |
Genomic Variants (DGV) | NPAS3 [DGVbeta] |
DECIPHER | NPAS3 [patients] [syndromes] [variants] [genes] |
CONAN: Copy Number Analysis | NPAS3 |
| Mutations |
ICGC Data Portal | NPAS3 |
TCGA Data Portal | NPAS3 |
Broad Tumor Portal | NPAS3 |
OASIS Portal | NPAS3 [ Somatic mutations - Copy number] |
Somatic Mutations in Cancer : COSMIC | NPAS3 [overview] [genome browser] [tissue] [distribution] |
Somatic Mutations in Cancer : COSMIC3D | NPAS3 |
Mutations and Diseases : HGMD | NPAS3 |
LOVD (Leiden Open Variation Database) | Whole genome datasets |
LOVD (Leiden Open Variation Database) | LOVD - Leiden Open Variation Database |
LOVD (Leiden Open Variation Database) | LOVD 3.0 shared installation |
BioMuta | search NPAS3 |
DgiDB (Drug Gene Interaction Database) | NPAS3 |
DoCM (Curated mutations) | NPAS3 (select the gene name) |
CIViC (Clinical Interpretations of Variants in Cancer) | NPAS3 (select a term) |
intoGen | NPAS3 |
Cancer3D | NPAS3(select the gene name) |
Impact of mutations | [PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser] |
| Diseases |
---|
OMIM | 609430 |
Orphanet | |
DisGeNET | NPAS3 |
Medgen | NPAS3 |
Genetic Testing Registry | NPAS3
|
NextProt | Q8IXF0 [Medical] |
TSGene | 64067 |
GENETests | NPAS3 |
Target Validation | NPAS3 |
Huge Navigator |
NPAS3 [HugePedia] |
snp3D : Map Gene to Disease | 64067 |
BioCentury BCIQ | NPAS3 |
ClinGen | NPAS3 |
| Clinical trials, drugs, therapy |
---|
Chemical/Protein Interactions : CTD | 64067 |
Chemical/Pharm GKB Gene | PA134968746 |
Clinical trial | NPAS3 |
| Miscellaneous |
---|
canSAR (ICR) | NPAS3 (select the gene name) |
DataMed Index | NPAS3 |
| Probes |
---|
| Litterature |
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PubMed | 40 Pubmed reference(s) in Entrez |
GeneRIFs | Gene References Into Functions (Entrez) |
CoreMine | NPAS3 |
EVEX | NPAS3 |
GoPubMed | NPAS3 |
iHOP | NPAS3 |