| Nomenclature |
|---|
| HGNC (Hugo) | NPAS4 18983 |
| Cards |
|---|
| Entrez_Gene (NCBI) | NPAS4 266743 neuronal PAS domain protein 4 |
| Aliases | Le-PAS; NXF; PASD10; bHLHe79 |
| GeneCards (Weizmann) | NPAS4 |
| Ensembl hg19 (Hinxton) | ENSG00000174576 [Gene_View] |
| Ensembl hg38 (Hinxton) | ENSG00000174576 [Gene_View] ENSG00000174576 [Sequence] chr11:66421004-66426706 [Contig_View] NPAS4 [Vega] |
| ICGC DataPortal | ENSG00000174576 |
| TCGA cBioPortal | NPAS4 |
| AceView (NCBI) | NPAS4 |
| Genatlas (Paris) | NPAS4 |
| WikiGenes | 266743 |
| SOURCE (Princeton) | NPAS4 |
| Genetics Home Reference (NIH) | NPAS4 |
| Genomic and cartography |
|---|
| GoldenPath hg38 (UCSC) | NPAS4 - chr11:66421004-66426706 + 11q13.2 [Description] (hg38-Dec_2013) |
| GoldenPath hg19 (UCSC) | NPAS4 - 11q13.2 [Description] (hg19-Feb_2009) |
NPAS4 - 11q13.2 [CytoView hg19] NPAS4 - 11q13.2 [CytoView hg38] |
| Mapping of homologs : NCBI | NPAS4 [Mapview hg19] NPAS4 [Mapview hg38] |
| OMIM | 608554 |
| Gene and transcription |
|---|
| Genbank (Entrez) | AB049469 AK094025 AK096253 BC105001 BC105003 |
| RefSeq transcript (Entrez) | NM_001318804 NM_178864 |
| RefSeq genomic (Entrez) | |
| Consensus coding sequences : CCDS (NCBI) | NPAS4 |
| Cluster EST : Unigene | Hs.256036 [ NCBI ] |
| CGAP (NCI) | Hs.256036 |
| Alternative Splicing Gallery | ENSG00000174576 |
| Gene Expression | NPAS4 [ NCBI-GEO ] NPAS4 [ EBI - ARRAY_EXPRESS ]
NPAS4 [ SEEK ] NPAS4 [ MEM ] |
| Gene Expression Viewer (FireBrowse) | NPAS4 [ Firebrowse - Broad ] |
| SOURCE (Princeton) | Expression in : [Datasets] [Normal Tissue Atlas] [carcinoma Classsification] [NCI60] |
| Genevestigator | Expression in : [tissues] [cell-lines] [cancer] [perturbations] |
| BioGPS (Tissue expression) | 266743 |
| GTEX Portal (Tissue expression) | NPAS4 |
| Human Protein Atlas | ENSG00000174576-NPAS4 [pathology] [cell] [tissue] |
| Protein : pattern, domain, 3D structure |
|---|
| UniProt/SwissProt | Q8IUM7 [function] [subcellular_location] [family_and_domains] [pathology_and_biotech] [ptm_processing] [expression] [interaction] |
| NextProt | Q8IUM7 [Sequence] [Exons] [Medical] [Publications] |
| With graphics : InterPro | Q8IUM7 |
| Splice isoforms : SwissVar | Q8IUM7 |
| PhosPhoSitePlus | Q8IUM7 |
| Domaine pattern : Prosite (Expaxy) | BHLH (PS50888) PAS (PS50112) |
| Domains : Interpro (EBI) | bHLH_dom PAS PAS_fold_3 |
| Domain families : Pfam (Sanger) | PAS_3 (PF08447) |
| Domain families : Pfam (NCBI) | pfam08447 |
| Domain families : Smart (EMBL) | PAS (SM00091) |
| Conserved Domain (NCBI) | NPAS4 |
| DMDM Disease mutations | 266743 |
| Blocks (Seattle) | NPAS4 |
| Superfamily | Q8IUM7 |
| Human Protein Atlas [tissue] | ENSG00000174576-NPAS4 [tissue] |
| Peptide Atlas | Q8IUM7 |
| HPRD | 12260 |
| IPI | IPI00216785 IPI00981383 |
| Protein Interaction databases |
|---|
| DIP (DOE-UCLA) | Q8IUM7 |
| IntAct (EBI) | Q8IUM7 |
| FunCoup | ENSG00000174576 |
| BioGRID | NPAS4 |
| STRING (EMBL) | NPAS4 |
| ZODIAC | NPAS4 |
| Ontologies - Pathways |
|---|
| QuickGO | Q8IUM7 |
| Ontology : AmiGO | RNA polymerase II core promoter proximal region sequence-specific DNA binding RNA polymerase II transcription factor activity, sequence-specific DNA binding transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding protein binding nucleus transcription factor complex transcription from RNA polymerase II promoter learning short-term memory long-term memory cell differentiation regulation of synaptic transmission, GABAergic social behavior positive regulation of transcription from RNA polymerase II promoter protein heterodimerization activity regulation of synaptic plasticity excitatory postsynaptic potential inhibitory postsynaptic potential cellular response to corticosterone stimulus postsynapse inhibitory synapse assembly |
| Ontology : EGO-EBI | RNA polymerase II core promoter proximal region sequence-specific DNA binding RNA polymerase II transcription factor activity, sequence-specific DNA binding transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding protein binding nucleus transcription factor complex transcription from RNA polymerase II promoter learning short-term memory long-term memory cell differentiation regulation of synaptic transmission, GABAergic social behavior positive regulation of transcription from RNA polymerase II promoter protein heterodimerization activity regulation of synaptic plasticity excitatory postsynaptic potential inhibitory postsynaptic potential cellular response to corticosterone stimulus postsynapse inhibitory synapse assembly |
| NDEx Network | NPAS4 |
| Atlas of Cancer Signalling Network | NPAS4 |
| Wikipedia pathways | NPAS4 |
| Orthology - Evolution |
|---|
| OrthoDB | 266743 |
| GeneTree (enSembl) | ENSG00000174576 |
| Phylogenetic Trees/Animal Genes : TreeFam | NPAS4 |
| HOGENOM | Q8IUM7 |
| Homologs : HomoloGene | NPAS4 |
| Homology/Alignments : Family Browser (UCSC) | NPAS4 |
| Gene fusions - Rearrangements |
|---|
| Fusion : Quiver | NPAS4 |
| Polymorphisms : SNP and Copy number variants |
|---|
| NCBI Variation Viewer | NPAS4 [hg38] |
| dbSNP Single Nucleotide Polymorphism (NCBI) | NPAS4 |
| dbVar | NPAS4 |
| ClinVar | NPAS4 |
| 1000_Genomes | NPAS4 |
| Exome Variant Server | NPAS4 |
| ExAC (Exome Aggregation Consortium) | ENSG00000174576 |
| GNOMAD Browser | ENSG00000174576 |
| Varsome Browser | NPAS4 |
| Genetic variants : HAPMAP | 266743 |
| Genomic Variants (DGV) | NPAS4 [DGVbeta] |
| DECIPHER | NPAS4 [patients] [syndromes] [variants] [genes] |
| CONAN: Copy Number Analysis | NPAS4 |
| Mutations |
|---|
| ICGC Data Portal | NPAS4 |
| TCGA Data Portal | NPAS4 |
| Broad Tumor Portal | NPAS4 |
| OASIS Portal | NPAS4 [ Somatic mutations - Copy number] |
| Somatic Mutations in Cancer : COSMIC | NPAS4 [overview] [genome browser] [tissue] [distribution] |
| Mutations and Diseases : HGMD | NPAS4 |
| LOVD (Leiden Open Variation Database) | Whole genome datasets |
| LOVD (Leiden Open Variation Database) | LOVD 3.0 shared installation |
| BioMuta | search NPAS4 |
| DgiDB (Drug Gene Interaction Database) | NPAS4 |
| DoCM (Curated mutations) | NPAS4 (select the gene name) |
| CIViC (Clinical Interpretations of Variants in Cancer) | NPAS4 (select a term) |
| intoGen | NPAS4 |
| Cancer3D | NPAS4(select the gene name) |
| Impact of mutations | [PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser] |
| Diseases |
|---|
| OMIM | 608554 |
| Orphanet | |
| DisGeNET | NPAS4 |
| Medgen | NPAS4 |
| Genetic Testing Registry | NPAS4
|
| NextProt | Q8IUM7 [Medical] |
| TSGene | 266743 |
| GENETests | NPAS4 |
| Target Validation | NPAS4 |
| Huge Navigator |
NPAS4 [HugePedia] |
| snp3D : Map Gene to Disease | 266743 |
| BioCentury BCIQ | NPAS4 |
| ClinGen | NPAS4 |
| Clinical trials, drugs, therapy |
|---|
| Chemical/Protein Interactions : CTD | 266743 |
| Chemical/Pharm GKB Gene | PA142671254 |
| Clinical trial | NPAS4 |
| Miscellaneous |
|---|
| canSAR (ICR) | NPAS4 (select the gene name) |
| DataMed Index | NPAS4 |
| Probes |
|---|
| Litterature |
|---|
| PubMed | 8 Pubmed reference(s) in Entrez |
| GeneRIFs | Gene References Into Functions (Entrez) |
| CoreMine | NPAS4 |
| EVEX | NPAS4 |
| GoPubMed | NPAS4 |
| iHOP | NPAS4 |
