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NPM2 (nucleophosmin/nucleoplasmin 2)

Identity

Other alias-
HGNC (Hugo) NPM2
LocusID (NCBI) 10361
Atlas_Id 70945
Location 8p21.3  [Link to chromosome band 8p21]
Location_base_pair Starts at 22024110 and ends at 22036897 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
NPM2 (8p21.3) / CDC16 (13q34)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)NPM2   7930
Cards
Entrez_Gene (NCBI)NPM2  10361  nucleophosmin/nucleoplasmin 2
Aliases
GeneCards (Weizmann)NPM2
Ensembl hg19 (Hinxton)ENSG00000158806 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000158806 [Gene_View]  chr8:22024110-22036897 [Contig_View]  NPM2 [Vega]
ICGC DataPortalENSG00000158806
TCGA cBioPortalNPM2
AceView (NCBI)NPM2
Genatlas (Paris)NPM2
WikiGenes10361
SOURCE (Princeton)NPM2
Genetics Home Reference (NIH)NPM2
Genomic and cartography
GoldenPath hg38 (UCSC)NPM2  -     chr8:22024110-22036897 +  8p21.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)NPM2  -     8p21.3   [Description]    (hg19-Feb_2009)
EnsemblNPM2 - 8p21.3 [CytoView hg19]  NPM2 - 8p21.3 [CytoView hg38]
Mapping of homologs : NCBINPM2 [Mapview hg19]  NPM2 [Mapview hg38]
OMIM608073   
Gene and transcription
Genbank (Entrez)AK094267 AK127602 AY262113 AY262114 BC068078
RefSeq transcript (Entrez)NM_001286680 NM_001286681 NM_182795
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)NPM2
Cluster EST : UnigeneHs.131055 [ NCBI ]
CGAP (NCI)Hs.131055
Alternative Splicing GalleryENSG00000158806
Gene ExpressionNPM2 [ NCBI-GEO ]   NPM2 [ EBI - ARRAY_EXPRESS ]   NPM2 [ SEEK ]   NPM2 [ MEM ]
Gene Expression Viewer (FireBrowse)NPM2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)10361
GTEX Portal (Tissue expression)NPM2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ86SE8   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ86SE8  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ86SE8
Splice isoforms : SwissVarQ86SE8
PhosPhoSitePlusQ86SE8
Domains : Interpro (EBI)Nucleoplasmin    Nucleoplasmin_core_dom   
Domain families : Pfam (Sanger)Nucleoplasmin (PF03066)   
Domain families : Pfam (NCBI)pfam03066   
Conserved Domain (NCBI)NPM2
DMDM Disease mutations10361
Blocks (Seattle)NPM2
PDB (SRS)3T30   
PDB (PDBSum)3T30   
PDB (IMB)3T30   
PDB (RSDB)3T30   
Structural Biology KnowledgeBase3T30   
SCOP (Structural Classification of Proteins)3T30   
CATH (Classification of proteins structures)3T30   
SuperfamilyQ86SE8
Human Protein AtlasENSG00000158806
Peptide AtlasQ86SE8
HPRD12160
IPIIPI00328389   IPI00977744   IPI00979080   IPI00432741   
Protein Interaction databases
DIP (DOE-UCLA)Q86SE8
IntAct (EBI)Q86SE8
FunCoupENSG00000158806
BioGRIDNPM2
STRING (EMBL)NPM2
ZODIACNPM2
Ontologies - Pathways
QuickGOQ86SE8
Ontology : AmiGOcytoplasmic chromatin  nuclear chromatin  chromatin binding  protein binding  nucleus  chromatin remodeling  regulation of exit from mitosis  single fertilization  embryo development  oocyte differentiation  covalent chromatin modification  enzyme binding  histone binding  positive regulation of catalytic activity  positive regulation of DNA replication  positive regulation of meiotic nuclear division  protein homooligomerization  
Ontology : EGO-EBIcytoplasmic chromatin  nuclear chromatin  chromatin binding  protein binding  nucleus  chromatin remodeling  regulation of exit from mitosis  single fertilization  embryo development  oocyte differentiation  covalent chromatin modification  enzyme binding  histone binding  positive regulation of catalytic activity  positive regulation of DNA replication  positive regulation of meiotic nuclear division  protein homooligomerization  
NDEx NetworkNPM2
Atlas of Cancer Signalling NetworkNPM2
Wikipedia pathwaysNPM2
Orthology - Evolution
OrthoDB10361
GeneTree (enSembl)ENSG00000158806
Phylogenetic Trees/Animal Genes : TreeFamNPM2
HOVERGENQ86SE8
HOGENOMQ86SE8
Homologs : HomoloGeneNPM2
Homology/Alignments : Family Browser (UCSC)NPM2
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerNPM2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)NPM2
dbVarNPM2
ClinVarNPM2
1000_GenomesNPM2 
Exome Variant ServerNPM2
ExAC (Exome Aggregation Consortium)NPM2 (select the gene name)
Genetic variants : HAPMAP10361
Genomic Variants (DGV)NPM2 [DGVbeta]
DECIPHERNPM2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisNPM2 
Mutations
ICGC Data PortalNPM2 
TCGA Data PortalNPM2 
Broad Tumor PortalNPM2
OASIS PortalNPM2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICNPM2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDNPM2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch NPM2
DgiDB (Drug Gene Interaction Database)NPM2
DoCM (Curated mutations)NPM2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)NPM2 (select a term)
intoGenNPM2
Cancer3DNPM2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM608073   
Orphanet
MedgenNPM2
Genetic Testing Registry NPM2
NextProtQ86SE8 [Medical]
TSGene10361
GENETestsNPM2
Target ValidationNPM2
Huge Navigator NPM2 [HugePedia]
snp3D : Map Gene to Disease10361
BioCentury BCIQNPM2
ClinGenNPM2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD10361
Chemical/Pharm GKB GenePA31732
Clinical trialNPM2
Miscellaneous
canSAR (ICR)NPM2 (select the gene name)
Probes
Litterature
PubMed15 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineNPM2
EVEXNPM2
GoPubMedNPM2
iHOPNPM2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed May 31 15:33:01 CEST 2017

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